Search Results - "Nie, Guohui"
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Carbon-based nanozymes for biomedical applications
Published in Nano research (01-03-2021)“…Nanozymes are nanomaterials with enzyme-like properties that have attracted significant interest owing to their capability to address the limitations of…”
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Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes
Published in Nature protocols (01-07-2018)“…Nanozymes are nanomaterials exhibiting intrinsic enzyme-like characteristics that have increasingly attracted attention, owing to their high catalytic…”
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3
Versatile Applications of Metal Single‐Atom @ 2D Material Nanoplatforms
Published in Advanced science (01-11-2019)“…Recently, emerging 2D material‐supported metal single‐atom catalysts (SACs) are receiving enormous attention in heterogeneous catalysis. Due to their…”
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Recent advances in anisotropic two-dimensional materials and device applications
Published in Nano research (01-04-2021)“…Two-dimensional (2D) materials, such as transition metal dichalcogenides (TMDs), black phosphorus (BP), MXene and borophene, have aroused extensive attention…”
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A Highly Sensitive CRISPR‐Empowered Surface Plasmon Resonance Sensor for Diagnosis of Inherited Diseases with Femtomolar‐Level Real‐Time Quantification
Published in Advanced science (01-05-2022)“…The clustered regularly interspaced short palindromic repeats (CRISPR) molecular system has emerged as a promising technology for the detection of nucleic…”
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Engineering cell signaling using tunable CRISPR–Cpf1-based transcription factors
Published in Nature communications (13-12-2017)“…The catalytically dead Cpf1 endonuclease from Acidaminococcus sp. BV3L6 (dAsCpf1) has been used to construct effective transcriptional repressors in bacteria…”
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7
Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy
Published in Light, science & applications (15-09-2020)“…Here, we describe a combination strategy of black phosphorus (BP)-based photothermal therapy together with anti-CD47 antibody (aCD47)-based immunotherapy to…”
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TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2
Published in Nano today (01-10-2021)“…•A TiO2 supported Ag atoms single atom nanozyme (Ag-TiO2 SAN) was rationally designed.•Ag-TiO2 SAN is produced by gram-scale synthesis and low cost comparing…”
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9
Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance
Published in Cell metabolism (03-07-2018)“…Intrinsic and evasive antiangiogenic drug (AAD) resistance is frequently developed in cancer patients, and molecular mechanisms underlying AAD resistance…”
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A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis
Published in Clinical cancer research (15-08-2017)“…Cancer metastasis can occur at the early stage of tumor development when a primary tumor is at the microscopic size. In particular, the interaction of…”
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Inhibiting DNA methylation alleviates cisplatin-induced hearing loss by decreasing oxidative stress-induced mitochondria-dependent apoptosis via the LRP1–PI3K/AKT pathway
Published in Acta pharmaceutica Sinica. B (01-03-2022)“…Cisplatin-related ototoxicity is a critical side effect of chemotherapy and can lead to irreversible hearing loss. This study aimed to assess the potential…”
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Two-Dimensional Platinum Diselenide: Synthesis, Emerging Applications, and Future Challenges
Published in Nano-micro letters (27-08-2020)“…Highlights A comprehensive review of the recent development of two-dimensional (2D) PtSe 2 synthesis strategies has been extensively surveyed. The applications…”
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13
Biochemistry of mammalian ferritins in the regulation of cellular iron homeostasis and oxidative responses
Published in Science China. Life sciences (01-03-2021)“…Ferritin, an iron-storage protein, regulates cellular iron metabolism and oxidative stress. The ferritin structure is characterized as a spherical cage, inside…”
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Two-Dimensional Borophene: Properties, Fabrication, and Promising Applications
Published in Research (Washington) (2020)“…Monoelemental two-dimensional (2D) materials (Xenes) aroused a tremendous attention in 2D science owing to their unique properties and extensive applications…”
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15
The DNA methylation inhibitor RG108 protects against noise-induced hearing loss
Published in Cell biology and toxicology (01-10-2021)“…Background Noise-induced hearing loss represents a commonly diagnosed type of hearing disability, severely impacting the quality of life of individuals. The…”
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MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma
Published in Cancer biology & therapy (03-10-2019)“…Nasopharyngeal carcinoma (NPC) is a high-risk head and neck cancer with poor clinical outcomes and insufficient treatments. The mouse double minute 2 homolog…”
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Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
Published in Nature communications (01-09-2016)“…The impact of discontinuation of anti-VEGF cancer therapy in promoting cancer metastasis is unknown. Here we show discontinuation of anti-VEGF treatment…”
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Functional Independence and Disability Evaluation in Stroke Patients: Optimal Cutoff Scores for a Pictorial-Based Longshi Scale, Barthel Index, and Modified Rankin Scale
Published in Frontiers in neurology (10-02-2022)“…The modified Rankin Scale (mRS) and Barthel Index (BI) are widely used to measure functional outcomes worldwide. The Longshi Scale (LS), a novel…”
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Comprehensive bulk and single-cell transcriptome profiling give useful insights into the characteristics of osteoarthritis associated synovial macrophages
Published in Frontiers in immunology (05-01-2023)“…Osteoarthritis (OA) is a common chronic joint disease, but the association between molecular and cellular events and the pathogenic process of OA remains…”
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Lsm14b controls zebrafish oocyte growth by regulating polyadenylation of the mRNA poly(A) tail
Published in Frontiers in Marine Science (04-09-2024)“…Lsm14b (LSM family member 14b) is a messenger ribonucleoprotein (mRNP) and a widely present component in eukaryotes. Lsm14b participates in oocyte development…”
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