Search Results - "Nicu, Elena A"
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Emerging Concepts in the Resolution of Periodontal Inflammation: A Role for Resolvin E1
Published in Frontiers in immunology (14-12-2017)“…Inflammatory response is a protective biological process intended to eliminate the harmful effect of the insulting influx. Resolution of inflammation…”
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Acquiring and maintaining a normal oral microbiome: current perspective
Published in Frontiers in cellular and infection microbiology (2014)“…The oral microbiota survives daily physical and chemical perturbations from the intake of food and personal hygiene measures, resulting in a long-term stable…”
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The evidence for placental microbiome and its composition in healthy pregnancies: A systematic review
Published in Journal of reproductive immunology (01-02-2022)“…•First systematic approach on this topic using structured quality bias assessment.•First review to examine the link of placental microbiome with oral…”
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Oral Neutrophils Characterized: Chemotactic, Phagocytic, and Neutrophil Extracellular Trap (NET) Formation Properties
Published in Frontiers in immunology (29-03-2019)“…Maintenance of oral health is in part managed by the immune-surveillance and antimicrobial functions of polymorphonuclear leukocytes (PMNs), which migrate from…”
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Characterization of oral polymorphonuclear neutrophils in periodontitis patients: a case-control study
Published in BMC oral health (24-08-2018)“…Maintaining oral health is a continuous and dynamic process that also involves the immune system. Polymorphonuclear neutrophils (PMNs) migrate from blood…”
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Genes Critical for Developing Periodontitis: Lessons from Mouse Models
Published in Frontiers in immunology (27-10-2017)“…Since the etiology of periodontitis in humans is not fully understood, genetic mouse models may pinpoint indispensable genes for optimal immunological…”
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A rapid, non-invasive tool for periodontitis screening in a medical care setting
Published in BMC oral health (23-05-2019)“…Since periodontitis is bi-directionally associated with several systemic diseases, such as diabetes mellitus and cardiovascular diseases, it is important for…”
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Oral polymorphonuclear neutrophil characteristics in relation to oral health: a cross-sectional, observational clinical study
Published in International journal of oral science (29-09-2016)“…Polymorphonuclear neutmphils (PMNs) have a major role in the innate immune system. However, little is known about PMN contribution in relation to oral health…”
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Survival, Retention, and Selective Proliferation of Lymphocytes Is Mediated by Gingival Fibroblasts
Published in Frontiers in immunology (25-07-2018)“…Periodontitis, a chronic inflammatory disease of the periodontium, is characterized by osteoclast-mediated alveolar bone destruction. Gingival fibroblasts…”
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Periodontal therapy increases neutrophil extracellular trap degradation
Published in Innate immunity (London, England) (01-07-2020)“…In periodontitis, polymorphonuclear leucocytes (PMNs) are activated. They entrap and eliminate pathogens by releasing neutrophil extracellular traps (NETs)…”
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The Possible Role of Neutrophils in the Induction of Osteoclastogenesis
Published in Journal of immunology research (2019)“…The ligand of the receptor activator of NF-κB (RANKL) is a key molecule in the formation of osteoclasts, the key cells that cause the disease-associated…”
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Polymorphonuclear neutrophils in periodontitis and their possible modulation as a therapeutic approach
Published in Periodontology 2000 (01-06-2016)“…The main focus of this review is polymorphonuclear neutrophilic granulocytes. Polymorphonuclear neutrophils play a pivotal role in normal host resistance to…”
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Impaired polymorphonuclear neutrophils in the oral cavity of edentulous individuals
Published in European journal of oral sciences (01-10-2017)“…Oral health is characterized by functional oral polymorphonuclear neutrophils (oPMNs). Edentulism might be associated with a loss of oPMNs because these cells…”
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Comparing periodontitis biomarkers in saliva, oral rinse and gingival crevicular fluid: A pilot study
Published in Journal of clinical periodontology (01-09-2021)“…Aim To explore the feasibility of screening for periodontitis by measuring biomarkers, namely total proteolytic activity (TPA), matrix metalloproteinase…”
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Oral Polymorphonuclear Neutrophil Contributes to Oral Health
Published in Current oral health reports (2018)“…Purpose of Review Oral health is maintained in a dynamic equilibrium between the host immunity and the oral microbiome. Oral polymorphonuclear neutrophils…”
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Association of serum immunoglobulin G (IgG) levels against two periodontal pathogens and prothrombotic state: a clinical pilot study
Published in Thrombosis journal (04-11-2010)“…Periodontitis is associated with cardiovascular diseases (CVD). In our previous studies a prothrombotic state has been observed in periodontitis, which…”
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Reduced platelet hyper-reactivity and platelet-leukocyte aggregation after periodontal therapy
Published in Thrombosis journal (06-02-2017)“…Platelets from untreated periodontitis patients are hyper-reactive and form more platelet-leukocyte complexes compared to cells from individuals without…”
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RCT comparing implants with turned and anodically oxidized surfaces: A pilot study, a 3-year follow-up
Published in Journal of clinical periodontology (01-12-2012)“…Aim This 3‐year prospective randomized controlled trial compared the clinical, microbiological and biochemical outcome of minimally (Turned, Tur) and…”
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Polymorphonuclear neutrophil integrity and functionality are preserved when exposed to saliva
Published in Archives of oral biology (01-08-2018)“…•Determine phenotypic changes of neutrophils after contact with human saliva.•Neutrophil morphology and function is not affected in the presence of…”
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Periodontitis is associated with platelet activation
Published in Atherosclerosis (01-02-2009)“…Abstract There is an epidemiological association between periodontitis and cardiovascular disease (CVD). In periodontitis, low grade systemic inflammation and…”
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