Search Results - "Nicotra, M. R."

Cyclooxygenase-2 (COX-2), Epidermal Growth Factor Receptor (EGFR), and Her-2/neu Expression in Ovarian Cancer by Ferrandina, G., Ranelletti, F.O., Lauriola, L., Fanfani, F., Legge, F., Mottolese, M., Nicotra, M.R., Natali, P.G., Zakut, V.H., Scambia, G.

“…Objectives. Cyclooxygenase-2 (COX-2) seems to be involved in critical steps of cancer onset and progression. Abnormalities of epidermal growth factor receptor…”
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Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas by OLIVERO, M, RIZZO, M, COMOGLIO, P. M, DI RENZO, M. F, MADEDDU, R, CASADIO, C, PENNACCHIETTI, S, NICOTRA, M. R, PRAT, M, MAGGI, G, ARENA, N, NATALI, P. G

“…Hepatocyte growth factor/scatter factor (HGF/SF) stimulates the invasive growth of epithelial cells via the c-MET oncogene-encoded receptor. In normal lung,…”
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Expression of endothelin 1 and endothelin a receptor in ovarian carcinoma : Evidence for an autocrine role in tumor growth by BAGNATO, A, SALANI, D, DI CASTRO, V, WU-WONG, J. R, TECCE, R, NICOTRA, M. R, VENUTI, A, NATALI, P. G

“…In the present study, we have investigated the expression of endothelin 1 (ET-1) and the ET(A) receptor (ET(A)R) and ET(B) receptor (ET(B)R) in primary (n =…”
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Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression by NATALI, P. G, NICOTRA, M. R, DI RENZO, M. F, PRAT, M, BIGOTTI, A, CAVALIERE, R, COMOGLIO, P. M

“…The c-MET proto-oncogene encodes the receptor for the Hepatocyte Growth Factor/Scatter Factor, which is known to mediate mitogenic, motogenic and invasive…”
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Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor by Natali, P G, Nicotra, M R, Winkler, A B, Cavaliere, R, Bigotti, A, Ullrich, A

“…Mutations at the white spotting (w) locus in mice have deleterious effects on germ cells, melanocytes and hematopoietic stem cells. The w locus encodes the…”
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A Tumor-Associated Fibronectin Isoform Generated by Alternative Splicing of Messenger RNA Precursors by Carnemolla, Barbara, Balza, Enrica, Siri, Annalisa, Zardi, Luciano, Nicotra, Maria Rita, Bigotti, Aldo, Natali, Pier Giorgio

“…Fibronectin (FN) represents the mixture of a number of structurally different molecules (isoforms) whose make-up varies depending on the FN sources. FN from…”
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Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours by UCCINI, S, COLAROSSI, C, CAPPELLI, C. A, COZZI, D, DONFRANCESCO, A, KOKAI, G, LOSTY, P. D, MCDOWELL, H. P, DOMINICI, C, SCARPINO, S, BOLDRINI, R, NATALI, P. G, NICOTRA, M. R, PERLA, F. M, MANNARINO, O, ALTAVISTA, P, BOGLINO, C

“…Multiple defects in apoptotic pathways have been described in peripheral neuroblastic tumours (NTs). Mitosis-karyorrhexis index (MKI) is a reliable…”
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Selective Changes in Expression of HLA Class I Polymorphic Determinants in Human Solid Tumors by Natali, P. G., Nicotra, M. R., Bigotti, A., Venturo, I., Marcenaro, L., Giacomini, P., Russo, C.

“…Analysis of surgical biopsies with monoclonal antibodies (mAbs) to framework determinants of major histocompatibility complex class I antigens has shown that…”
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Breast cancer is associated with loss of the c-kit oncogene product by Natali, P G, Nicotra, M R, Sures, I, Mottolese, M, Botti, C, Ullrich, A

“…The proto-oncogene c-kit encodes a tyrosine kinase receptor related to the PDGF/CSF-1 receptors. Mutations of this gene result in impairment of hematopoiesis,…”
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The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors by Prat, M, Narsimhan, R P, Crepaldi, T, Nicotra, M R, Natali, P G, Comoglio, P M

“…The human c-MET oncogene encodes a transmembrane tyrosine kinase (p190c-met) with structural and functional features of a growth-factor receptor. Monoclonal…”
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Overexpression of the met/HGF receptor in renal cell carcinomas by Natali, Pier Giorgio, Prat, Maria, Nicotra, Maria Rita, Bigotti, Aldo, Olivero, Martina, Comoglio, Paolo M., Di Renzo, Maria Flavia

“…The c‐met oncogene encodes the receptor for hepatocyte growth factor/scatter factor (HGF/SF), a multifunctional cytokine able to mediate morphogenesis as well…”
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Expression of c-kit receptor in normal and transformed human nonlymphoid tissues by NATALI, P. G, NICOTRA, M. R, SURES, I, SANTORO, E, BIGOTTI, A, ULLRICH, A

“…The protooncogene c-kit encodes a tyrosine kinase with a molecular weight of 145,000, highly related to the platelet derived growth factor/colony stimulating…”
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Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions by NATALI, P, NICOTRA, M. R, CAVALIERE, R, BIGOTTI, A, ROMANO, G, TEMPONI, M, FERRONE, S

“…Immunochemical studies have shown that the monoclonal antibody (MoAb) CL203.4, elicited with immune interferon treated cultured human melanoma cells Colo 38,…”
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Expression of fibronectin, fibronectin isoforms and integrin receptors in melanocytic lesions by NATALI, P. G, NICOTRA, M. R, DI FILIPPO, F, BIGOTTI, A

“…In vitro studies have demonstrated that fibronectin (FN) can deliver a mitogenic signal to quiescent human melanoma cells and that the alpha 5/beta 1-integrin…”
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Integrin expression in cutaneous malignant melanoma: association of the alpha 3/beta 1 heterodimer with tumor progression by Natali, P G, Nicotra, M R, Bartolazzi, A, Cavaliere, R, Bigotti, A

“…The cell-surface heterodimers of the integrin family of molecules, which mediate cell-cell and cell-substratum interactions, are likely to be functionally…”
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Expression and structural features of endoglin (CD105), a transforming growth factor β1 and β3 binding protein, in human melanoma by ALTOMONTE, M, MONTAGNER, R, FONSATTI, E, COLIZZI, F, CATTAROSSI, I, BRASOVEANU, L. I, NICOTRA, M. R, CATTELAN, A, NATALI, P. G, MAIO, M

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Changes in expression of alpha 6/beta 4 integrin heterodimer in primary and metastatic breast cancer by Natali, P G, Nicotra, M R, Botti, C, Mottolese, M, Bigotti, A, Segatto, O

“…The alpha 6/beta 4 integrin complex has been shown to be expressed in murine tissues at the basolateral aspect of most epithelial cells including the mammary…”
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Hemopoietic progenitor cells in atopic dermatitis skin lesions by Mastrandrea, F, Cadario, G, Nicotra, M R, Natali, P G

“…We have recently shown the expression of lymphoid early developmental markers, including CD104, Thy 1, CD1a, Pgp-1 and TdT, by the cells constituting atopic…”
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Expression of the p185 encoded by HER2 oncogene in normal and transformed human tissues by Natali, P G, Nicotra, M R, Bigotti, A, Venturo, I, Slamon, D J, Fendly, B M, Ullrich, A

“…The human homolog of the rat neu oncogene, HER2 (also termed c-erbB2) has been demonstrated in amplified form in human breast tumors with poor prognosis…”
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Comparative analysis of the expression of the extracellular matrix protein tenascin in normal human fetal, adult and tumor tissues by Natali, P G, Nicotra, M R, Bigotti, A, Botti, C, Castellani, P, Risso, A M, Zardi, L

“…Tenascin (TN) is a high-molecular-mass oligomeric glycoprotein of the extracellular matrix (ECM) endowed with a programmed expression in embryonic life and a…”
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