Search Results - "Nicolson, Shannon"

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy by Nicolson, Shannon, Manning, Jantina A., Lim, Yoon, Jiang, Xin, Kolze, Erica, Dayan, Sonia, Umargamwala, Ruchi, Xu, Tianqi, Sandow, Jarrod J., Webb, Andrew I., Kumar, Sharad, Denton, Donna

“…Autophagy, the process of elimination of cellular components by lysosomal degradation, is essential for animal development and homeostasis. Using the…”
Get full text

A screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defect by Shaukat, Zeeshan, Wong, Heidi W S, Nicolson, Shannon, Saint, Robert B, Gregory, Stephen L

“…The spindle assembly checkpoint is crucial for the maintenance of a stable chromosome number. Defects in the checkpoint lead to Chromosomal INstability (CIN),…”
Get full text

UTX coordinates steroid hormone-mediated autophagy and cell death by Denton, Donna, Aung-Htut, May T., Lorensuhewa, Nirmal, Nicolson, Shannon, Zhu, Wenying, Mills, Kathryn, Cakouros, Dimitrios, Bergmann, Andreas, Kumar, Sharad

Get full text

Dpp regulates autophagy-dependent midgut removal and signals to block ecdysone production by Denton, Donna, Xu, Tianqi, Dayan, Sonia, Nicolson, Shannon, Kumar, Sharad

“…Animal development and homeostasis require the programmed removal of cells. Autophagy-dependent cell deletion is a unique form of cell death often involved in…”
Get full text

Ecdysone-mediated programmed cell death in Drosophila by Nicolson, Shannon, Denton, Donna, Kumar, Sharad

“…During Drosophila development, the steroid hormone ecdysone plays a key role in the transition from embryo into larva and then into pupa. It is during…”
Get full text

Cp1/cathepsin L is required for autolysosomal clearance in Drosophila by Xu, Tianqi, Nicolson, Shannon, Sandow, Jarrod J., Dayan, Sonia, Jiang, Xin, Manning, Jantina A., Webb, Andrew I., Kumar, Sharad, Denton, Donna

“…Macroautophagy/autophagy is a highly conserved lysosomal degradative pathway important for maintaining cellular homeostasis. Much of our current knowledge of…”
Get full text

Crosstalk between Dpp and Tor signaling coordinates autophagy-dependent midgut degradation by Denton, Donna, Xu, Tianqi, Dayan, Sonia, Nicolson, Shannon, Kumar, Sharad

“…The majority of developmentally programmed cell death (PCD) is mediated by caspase-dependent apoptosis; however, additional modalities, including…”
Get full text

UTX coordinates steroid hormone-mediated autophagy and cell death by Denton, Donna, Aung-Htut, May T., Lorensuhewa, Nirmal, Nicolson, Shannon, Zhu, Wenying, Mills, Kathryn, Cakouros, Dimitrios, Bergmann, Andreas, Kumar, Sharad

“…Correct spatial and temporal induction of numerous cell type-specific genes during development requires regulated removal of the repressive histone H3 lysine…”
Get full text

Clinical Impact of Comprehensive Molecular Profiling in Adolescents and Young Adults with Sarcoma by Andrew, Eden C, Lewin, Jeremy, Desai, Jayesh, Orme, Lisa, Hamilton, Anne, Bae, Susie, Zhu, Wenying, Nicolson, Shannon, Varghese, Leila N, Mitchell, Camilla B, Vissers, Joseph H A, Xu, Huiling, Grimmond, Sean M, Fox, Stephen B, Luen, Stephen J

“…Sarcomas are a heterogenous group of tumours that commonly carry poor prognosis with limited therapeutic options. Adolescents and young adults (AYAs) with…”
Get full text