Search Results - "Nicolau, Dan V"

Parallel computation with molecular-motor-propelled agents in nanofabricated networks by Nicolau, Dan V., Lard, Mercy, Korten, Till, van Delft, Falco C. M. J. M., Persson, Malin, Bengtsson, Elina, Månsson, Alf, Diez, Stefan, Linke, Heiner, Nicolau, Dan V.

“…The combinatorial nature of many important mathematical problems, including nondeterministic-polynomial-time (NP)-complete problems, places a severe limitation…”
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Inhaled corticosteroids in virus pandemics: a treatment for COVID-19? by Nicolau, Dan V, Bafadhel, Mona

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Mapping hydrophobicity on the protein molecular surface at atom-level resolution by Nicolau, Jr, Dan V, Paszek, Ewa, Fulga, Florin, Nicolau, Dan V

“…A precise representation of the spatial distribution of hydrophobicity, hydrophilicity and charges on the molecular surface of proteins is critical for the…”
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Intracellular mechanisms of fungal space searching in microenvironments by Held, Marie, Kašpar, Ondřej, Edwards, Clive, Nicolau, Dan V.

“…Filamentous fungi that colonize microenvironments, such as animal or plant tissue or soil, must find optimal paths through their habitat, but the biological…”
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Conformational Spread as a Mechanism for Cooperativity in the Bacterial Flagellar Switch by Bai, Fan, Branch, Richard W., Nicolau, Dan V., Pilizota, Teuta, Steel, Bradley C., Maini, Philip K., Berry, Richard M.

“…The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been…”
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Patterns of bacterial motility in microfluidics-confining environments by Tokárova, Viola, Perumal, Ayyappasamy Sudalaiyadum, Nayak, Monalisha, Shum, Henry, Kašpar, Ondřej, Rajendran, Kavya, Mohammadi, Mahmood, Tremblay, Charles, Gaffney, Eamonn A., Martel, Sylvain, Nicolau, Dan V.

“…Understanding the motility behavior of bacteria in confining microenvironments, in which they search for available physical space and move in response to…”
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Protein Adsorption on Solid Surfaces: Data Mining, Database, Molecular Surface-Derived Properties, and Semiempirical Relationships by Cho, Matthew, Mahmoodi, Zahra, Shetty, Prasad, Harrison, Lauren R., Arias Montecillo, Maru, Perumal, Ayyappasamy Sudalaiyadum, Solana, Gerardin, Nicolau, Dan V., Nicolau, Dan V.

“…Protein adsorption on solid surfaces is a process relevant to biological, medical, industrial, and environmental applications. Despite this wide interest and…”
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Design of network-based biocomputation circuits for the exact cover problem by Korten, Till, Diez, Stefan, Linke, Heiner, Nicolau, Dan V, Kugler, Hillel

“…Abstract Exact cover is a non-deterministic polynomial time (NP)—complete problem that is central to optimization challenges such as airline fleet planning and…”
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Biosensing using antibody-modulated motility of actin filaments on myosin-coated surfaces by Kekic, Murat, Hanson, Kristi L, Perumal, Ayyappasamy Sudalaiyadum, Solana, Gerardin, Rajendran, Kavya, Dash, Shantoshini, Nicolau, Jr, Dan V, Dobroiu, Serban, Dos Remedios, Cristobal G, Nicolau, Dan V

“…Motor proteins, such as myosin and kinesin, are biological molecular motors involved in force generation and intracellular transport within living cells. The…”
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Effects of defective motors on the active transport in biosensors powered by biomolecular motors by Kang'iri, Samuel Macharia, Salem, Andrew, Nicolau, Dan V., Nitta, Takahiro

“…Motor proteins, such as myosin and kinesin, are biological molecular motors involved in force generation and intracellular transport in living cells. They were…”
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Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial by Ramakrishnan, Sanjay, Nicolau, Dan V, Langford, Beverly, Mahdi, Mahdi, Jeffers, Helen, Mwasuku, Christine, Krassowska, Karolina, Fox, Robin, Binnian, Ian, Glover, Victoria, Bright, Stephen, Butler, Christopher, Cane, Jennifer L, Halner, Andreas, Matthews, Philippa C, Donnelly, Louise E, Simpson, Jodie L, Baker, Jonathan R, Fadai, Nabil T, Peterson, Stefan, Bengtsson, Thomas, Barnes, Peter J, Russell, Richard E K, Bafadhel, Mona

“…Multiple early reports of patients admitted to hospital with COVID-19 showed that patients with chronic respiratory disease were significantly…”
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Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial by Yu, Ly-Mee, Bafadhel, Mona, Dorward, Jienchi, Hayward, Gail, Saville, Benjamin R, Gbinigie, Oghenekome, Van Hecke, Oliver, Ogburn, Emma, Evans, Philip H, Thomas, Nicholas P B, Patel, Mahendra G, Richards, Duncan, Berry, Nicholas, Detry, Michelle A, Saunders, Christina, Fitzgerald, Mark, Harris, Victoria, Shanyinde, Milensu, de Lusignan, Simon, Andersson, Monique I, Barnes, Peter J, Russell, Richard E K, Nicolau, Dan V, Ramakrishnan, Sanjay, Hobbs, F D Richard, Butler, Christopher C, Yu, Ly-Mee, Bafadhel, Mona, Dorward, Jienchi, Hayward, Gail, Saville, Benjamin R, Gbinigie, Oghenekome, van Hecke, Oliver, Ogburn, Emma, Evans, Philip H, Thomas, Nicholas PB, Patel, Mahendra G, Richards, Duncan, Berry, Nicholas, Detry, Michelle A, Saunders, Christina T, Fitzgerald, Mark, Harris, Victoria, Shanyinde, Milensu, de Lusignan, Simon, Andersson, Monique I, Barnes, Peter J, Russell, Richard EK, Nicolau, Dan V, Ramakrishnan, Sanjay, Hobbs, FD Richard, Butler, Christopher C

“…A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in patients not admitted to hospital, but effectiveness in high-risk individuals…”
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Hydrophobic Recovery of PDMS Surfaces in Contact with Hydrophilic Entities: Relevance to Biomedical Devices by Tsuzuki, Tomoo, Baassiri, Karine, Mahmoudi, Zahra, Perumal, Ayyappasamy Sudalaiyadum, Rajendran, Kavya, Rubies, Gala Montiel, Nicolau, Dan V

“…Polydimethylsiloxane (PDMS), a silicone elastomer, is increasingly being used in health and biomedical fields due to its excellent optical and mechanical…”
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Mathematical Models of Cancer Cell Plasticity by Nicolau, Dan V., Burrage, Kevin, Burrage, Pamela M., Weerasinghe, Hasitha N.

“…Quantitative modelling is increasingly important in cancer research, helping to integrate myriad diverse experimental data into coherent pictures of the…”
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Molecularly imprinted polymer membranes and thin films for the separation and sensing of biomacromolecules by Boysen, Reinhard I., Schwarz, Lachlan J., Nicolau, Dan V., Hearn, Milton T. W.

“…This review describes recent advances associated with the development of surface imprinting methods for the synthesis of polymeric membranes and thin films,…”
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Effect of physicochemical parameters on the stability and activity of garlic alliinase and its use for in-situ allicin synthesis by Janská, Petra, Knejzlík, Zdeněk, Perumal, Ayyappasamy Sudalaiyadum, Jurok, Radek, Tokárová, Viola, Nicolau, Dan V, Štěpánek, František, Kašpar, Ondřej

“…Garlic is a well-known example of natural self-defence system consisting of an inactive substrate (alliin) and enzyme (alliinase) which, when combined, produce…”
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As good as it gets: a scaling comparison of DNA computing, network biocomputing, and electronic computing approaches to an NP-complete problem by Sudalaiyadum Perumal, Ayyappasamy, Wang, Zihao, Ippoliti, Giulia, van Delft, Falco C M J M, Kari, Lila, Nicolau, Dan V

“…Abstract All known algorithms to solve nondeterministic polynomial (NP) complete problems, relevant to many real-life applications, require the exploration of…”
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Identifying Optimal Lipid Raft Characteristics Required To Promote Nanoscale Protein-Protein Interactions on the Plasma Membrane by Nicolau, Dan V., Burrage, Kevin, Parton, Robert G., Hancock, John F.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Infection, inflammation and intervention: mechanistic modelling of epithelial cells in COVID-19 by Fadai, Nabil T, Sachak-Patwa, Rahil, Byrne, Helen M, Maini, Philip K, Bafadhel, Mona, Nicolau, Jr, Dan V

“…While the pathological mechanisms in COVID-19 illness are still poorly understood, it is increasingly clear that high levels of pro-inflammatory mediators play…”
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Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis by Baker, Jonathan R, Mahdi, Mahdi, Nicolau, Dan V, Ramakrishnan, Sanjay, Barnes, Peter J, Simpson, Jodie L, Cass, Steven P, Russell, Richard E K, Donnelly, Louise E, Bafadhel, Mona

“…Community-based clinical trials of the inhaled corticosteroid budesonide in early COVID-19 have shown improved patient outcomes. We aimed to understand the…”
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