Search Results - "Nicolas, Francisco José"
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Oleanolic acid stimulation of cell migration involves a biphasic signaling mechanism
Published in Scientific reports (05-09-2022)“…Cell migration is a critical process for wound healing, a physiological phenomenon needed for proper skin restoration after injury. Wound healing can be…”
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Oleanolic Acid Complexation with Cyclodextrins Improves Its Cell Bio-Availability and Biological Activities for Cell Migration
Published in International journal of molecular sciences (01-10-2023)“…Wound healing is a complex process to restore skin. Plant-derived bioactive compounds might be a source of substances for the treatment of wounds stalled in a…”
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Fibroin and sericin from Bombyx mori silk stimulate cell migration through upregulation and phosphorylation of c-Jun
Published in PloS one (31-07-2012)“…Wound healing is a biological process directed to the restoration of tissue that has suffered an injury. An important phase of wound healing is the generation…”
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Oleanolic acid induces migration in Mv1Lu and MDA-MB-231 epithelial cells involving EGF receptor and MAP kinases activation
Published in PloS one (23-02-2017)“…During wound healing, skin function is restored by the action of several cell types that undergo differentiation, migration, proliferation and/or apoptosis…”
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SIRT1 and Estrogen Signaling Cooperation for Breast Cancer Onset and Progression
Published in Frontiers in endocrinology (Lausanne) (27-09-2018)“…Breast cancer remains a significant female mortality cause. It constitutes a multifactorial disease for which research on environmental factors offers little…”
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Oleanolic acid rescues critical features of umbilical vein endothelial cells permanently affected by hyperglycemia
Published in Frontiers in endocrinology (Lausanne) (13-12-2023)“…Skin wound healing is a physiological process that involves several cell types. Among them, endothelial cells are required for inflammation resolution and…”
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New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
Published in Experimental & molecular medicine (01-02-2020)“…Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to…”
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Chronic Wound Healing by Amniotic Membrane: TGF-β and EGF Signaling Modulation in Re-epithelialization
Published in Frontiers in bioengineering and biotechnology (06-07-2021)“…The application of amniotic membrane (AM) on chronic wounds has proven very effective at resetting wound healing, particularly in re-epithelialization…”
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Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway
Published in Biomedicine & pharmacotherapy (01-06-2024)“…Rearrangement of the actin cytoskeleton is a prerequisite for carcinoma cells to develop cellular protrusions, which are required for migration, invasion, and…”
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Amniotic membrane stimulates cell migration by modulating transforming growth factor‐β signalling
Published in Journal of tissue engineering and regenerative medicine (01-03-2018)“…Keratinocyte migration is a mandatory aspect of wound healing. We have previously shown that amniotic membrane (AM) applied to chronic wounds assists healing…”
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Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription
Published in Cell communication and signaling (29-11-2017)“…The simplicity of Transforming Growth Factor ß (TGFβ) signaling pathway, linear and non-amplified, hardly sustains its variety of responses. This is often…”
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Effect of the Human Amniotic Membrane on the Umbilical Vein Endothelial Cells of Gestational Diabetic Mothers: New Insight on Inflammation and Angiogenesis
Published in Frontiers in bioengineering and biotechnology (05-07-2022)“…One of the most relevant diabetes complications is impaired wound healing, mainly characterized by reduced peripheral blood flow and diminished…”
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Management of Foot Ulcers and Chronic Wounds with Amniotic Membrane in Comorbid Patients: A Successful Experience
Published in Biomedicines (18-10-2024)“…Chronic wounds are defined as those with disturbances in normal healing. They involve symptoms like exudate, odor, pain or impaired mobility, severely…”
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Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells
Published in Journal of molecular medicine (Berlin, Germany) (01-03-2020)“…Tumor invasion and metastasis involve processes in which actin cytoskeleton rearrangement induced by Fascin1 plays a crucial role. Indeed, Fascin1 has been…”
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Microscopy Based Methods for the Assessment of Epithelial Cell Migration During In Vitro Wound Healing
Published in Journal of visualized experiments (02-01-2018)“…Cell migration is a mandatory aspect for wound healing. Creating artificial wounds on research animal models often results in costly and complicated…”
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The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo
Published in Cancers (18-02-2021)“…Fascin1 is the key actin-bundling protein involved in cancer invasion and metastasis whose expression is associated with bad prognosis in tumor from different…”
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Saharan Dust Events over the Valencian Community (Eastern Iberian Peninsula): Synoptic Circulation Patterns and Contribution to PM10 Levels
Published in Aerosol and air quality research (01-11-2020)“…This study assessed Saharan dust events (SDE) passing over the Valencian Community (VC; eastern Spain) during the period of 2014–2017 by investigating the…”
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The Impact of Intense Winter Saharan Dust Events on PM and Optical Properties at Urban Sites in the Southeast of the Iberian Peninsula
Published in Atmosphere (01-11-2021)“…The influence of three Saharan dust events (SDE) on particulate matter (PM) concentrations and aerosol optical properties (AOP) during February 2021 was…”
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Correction: Amniotic Membrane Modifies the Genetic Program Induced by TGFß, Stimulating Keratinocyte Proliferation and Migration in Chronic Wounds
Published in PloS one (15-10-2015)Get full text
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