Search Results - "Nicolai, E"

Dexamethasone alleviates tumor-associated brain damage and angiogenesis by Fan, Zheng, Sehm, Tina, Rauh, Manfred, Buchfelder, Michael, Eyupoglu, Ilker Y, Savaskan, Nicolai E

“…Children and adults with the most aggressive form of brain cancer, malignant gliomas or glioblastoma, often develop cerebral edema as a life-threatening…”
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Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis by Sehm, Tina, Rauh, Manfred, Wiendieck, Kurt, Buchfelder, Michael, Eyüpoglu, IIker Y, Savaskan, Nicolai E

“…The glutamate exchanger xCT (SLC7a11) is causally linked with the malignancy grade of brain tumors and represents a key player in glutamate, cystine and…”
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Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages by Choi, Judy, Stradmann-Bellinghausen, Beate, Yakubov, Eduard, Savaskan, Nicolai E, Régnier-Vigouroux, Anne

“…Glioblastoma cells produce and release high amounts of glutamate into the extracellular milieu and subsequently can trigger seizure in patients…”
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Comparison of CE-FDG-PET/CT with CE-FDG-PET/MR in the evaluation of osseous metastases in breast cancer patients by Catalano, O A, Nicolai, E, Rosen, B R, Luongo, A, Catalano, M, Iannace, C, Guimaraes, A, Vangel, M G, Mahmood, U, Soricelli, A, Salvatore, M

“…Background: Despite improvements in treatments, metastatic breast cancer remains difficult to cure. Bones constitute the most common site of first-time…”
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Sunitinib impedes brain tumor progression and reduces tumor‐induced neurodegeneration in the microenvironment by Hatipoglu, Gökçe, Hock, Stefan W., Weiss, Ruth, Fan, Zheng, Sehm, Tina, Ghoochani, Ali, Buchfelder, Michael, Savaskan, Nicolai E., Eyüpoglu, Ilker Y.

“…Malignant gliomas can be counted to the most devastating tumors in humans. Novel therapies do not achieve significant prolonged survival rates. The cancer…”
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Prostate cancer survivors with symptoms of radiation cystitis have elevated fibrotic and vascular proteins in urine by Zwaans, Bernadette M M, Nicolai, Heinz E, Chancellor, Michael B, Lamb, Laura E

“…Radiation for pelvic cancers can result in severe bladder damage and radiation cystitis (RC), which is characterized by chronic inflammation, fibrosis, and…”
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Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema by Savaskan, Nicolai E, Eyüpoglu, Ilker Y, Heckel, Alexandra, Hahnen, Eric, Engelhorn, Tobias, Doerfler, Arnd, Ganslandt, Oliver, Nimsky, Christopher, Buchfelder, Michael

“…Neurodegeneration and brain edema are hallmarks of human malignant brain tumors. Here we show that genetic or pharmacological inhibition of the glutamate…”
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Humoral antibody response following mRNA vaccines against SARS-CoV-2 in solid organ transplant recipients; a status after a fifth and bivalent vaccine dose by Christophorou, Emma, Nilsson, Anna Christine, Petersen, Inge, Lindvig, Susan O, Davidsen, Jesper R, Abazi, Rozeta, Poulsen, Mikael K, Pedersen, Rune M, Justesen, Ulrik S, Johansen, Nicolai E, Bistrup, Claus, Madsen, Lone W, Johansen, Isik S

“…In solid organ transplant (SOT) recipients, the humoral response following COVID-19 vaccination is reduced, as a result of their immunosuppressed treatment. In…”
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Comparative Analysis of Selenocysteine Machinery and Selenoproteome Gene Expression in Mouse Brain Identifies Neurons as Key Functional Sites of Selenium in Mammals by Zhang, Yan, Zhou, You, Schweizer, Ulrich, Savaskan, Nicolai E., Hua, Deame, Kipnis, Jonathan, Hatfield, Dolph L., Gladyshev, Vadim N.

“…Although dietary selenium (Se) deficiency results in phenotypes associated with selenoprotein depletion in various organs, the brain is protected from Se loss…”
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Simultaneous PET/MR head–neck cancer imaging: Preliminary clinical experience and multiparametric evaluation by Covello, M, Cavaliere, C, Aiello, M, Cianelli, M.S, Mesolella, M, Iorio, B, Rossi, A, Nicolai, E

“…Highlights • Simultaneous PET/MRI is a suitable tool for head/neck T-staging. • No significant differences have been found for PET measures get by both PET/CT…”
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Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury by Broggini, Thomas, Schnell, Lisa, Ghoochani, Ali, Mateos, José María, Buchfelder, Michael, Wiendieck, Kurt, Schäfer, Michael K, Eyupoglu, Ilker Y, Savaskan, Nicolai E

“…The Plasticity Related Gene family covers five, brain-specific, transmembrane proteins (PRG1-5, also termed LPPR1-5) that operate in neuronal plasticity during…”
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Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function by Savaskan, Nicolai E, Ufer, Christoph, Kühn, Hartmut, Borchert, Astrid

“…Selenoproteins have been recognized as modulators of brain function and signaling. Phospholipid hydroperoxide glutathione peroxidase (GPx4/PHGPx) is a unique…”
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Sevoflurane sparing effect of morphine in tegus (Salvator merianae) – a preliminary study by Carregaro, Adriano Bonfim, Bressan, Thais Feres, Xavier, Nathalia Villaça, Silva, André Nicolai E., Justo, André Augusto, Myiashiro, Vitor Yuji, Sanches, Mariana Cardoso

“…This study aimed to determine the minimum anesthetic concentration (MAC) of sevoflurane in tegus (Salvator merianae) and the morphine-sparing effect on this…”
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Epigenetics in Brain Tumors: HDACs Take Center Stage by Eyüpoglu, Ilker Y, Savaskan, Nicolai E

“…Primary tumors of the brain account for 2 % of all cancers with malignant gliomas taking the lion's share with 70 %. Malignant gliomas (high grade gliomas WHO°…”
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Intraoperative vascular DIVA surgery reveals angiogenic hotspots in tumor zones of malignant gliomas by Eyüpoglu, Ilker Y., Hore, Nirjhar, Fan, Zheng, Buslei, Rolf, Merkel, Andreas, Buchfelder, Michael, Savaskan, Nicolai E.

“…Malignant gliomas belong to the most threatening tumor entities and are hallmarked by rapid proliferation, hypervascularization and an invasive growth pattern…”
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2-deoxy-2[F-18] fluoro-D-glucose positron emission tomography Deauville scale and core-needle biopsy to determine successful management after six doxorubicin, bleomycin, vinblastine and dacarbazine cycles in advanced-stage Hodgkin lymphoma by Picardi, M., Fonti, R., Della Pepa, R., Giordano, C., Pugliese, N., Nicolai, E., Salvatore, M., Mainolfi, C., Venetucci, P., Rascato, M.G., Cappuccio, I., Mascolo, M., Vigliar, E., Troncone, G., Del Vecchio, S., Pane, F.

“…The clinical impact of the positivity of the Deauville scale (DS) of positron emission tomography (PET) performed at the end of doxorubicin, bleomycin,…”
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Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: Specific induction of enzyme expression in reactive astrocytes following brain injury by Savaskan, Nicolai E., Borchert, Astrid, Bräuer, Anja U., Kuhn, Hartmut

“…Glutathione peroxidase-4 (GPx4) is a multifunctional selenoprotein expressed as mitochondrial, cytosolic, or nuclear isoforms. As a catalytically active enzyme…”
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Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease by Mauro, F R, Chauvie, S, Paoloni, F, Biggi, A, Cimino, G, Rago, A, Gentile, M, Morabito, F, Coscia, M, Bellò, M, Sacchetti, G M, Rossi, D, Laurenti, L, Autore, F, Campanelli, M, Trastulli, F, Nicolai, E, Riminucci, M, Gaidano, G, Guarini, A, Gallamini, A, Foà, R

“…In order to evaluate the predictive value of positron emission tomography–computed tomography (PET/CT) in discriminating the presence of a Richter’s syndrome…”
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PET/MRI for staging patients with Hodgkin lymphoma: equivalent results with PET/CT in a prospective trial by Picardi, M., Cavaliere, C., Della Pepa, R., Nicolai, E., Soricelli, A., Giordano, C., Pugliese, N., Rascato, M.G., Cappuccio, I., Campagna, G., Cerchione, C., Vigliar, E., Troncone, G., Mascolo, M., Franzese, M., Castaldo, R., Salvatore, M., Pane, F.

“…To compare FDG-PET/unenhanced MRI and FDG-PET/diagnostic CT in detecting infiltration in patients with newly diagnosed Hodgkin lymphoma (HL). The endpoint was…”
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New Identification Approach and Methods for Plasma Equilibrium Reconstruction in D-Shaped Tokamaks by Mitrishkin, Yuri V., Korenev, Pavel S., Konkov, Artem E., Kruzhkov, Valerii I., Ovsiannikov, Nicolai E.

“…The paper deals with the identification of plasma equilibrium reconstruction in D-shaped tokamaks on the base of plasma external magnetic measurements. The…”
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