Search Results - "Nicola, N.A"

The role of leukemia inhibitory factor in tubal ectopic pregnancy by Krishnan, T, Winship, A, Sonderegger, S, Menkhorst, E, Horne, A.W, Brown, J, Zhang, J.-G, Nicola, N.A, Tong, S, Dimitriadis, E

“…Abstract Introduction Ectopic pregnancy is unique to humans and a leading cause of maternal morbidity and mortality. The etiology remains unknown however…”
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Murine Oncostatin M (mOSM) regulates osetoblastic genes through a novel receptor by Walker, E.C, McGregor, N.E, Poulton, I.J, Solano, M, Zhang, J, Nicola, N.A, Gillespie, M.T, Martin, T.J, Sims, N.A

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Development of a vaginally applied, non-hormonal contraceptive: the contraceptive efficacy and impact on bone turnover of PEGLA, a long-acting LIF antagonist by Menkhorst, E, Zhang, J.G, Morgan, P.O, Poulton, I.J, Metcalf, D, Salamonsen, L.A, Sims, N.A, Nicola, N.A, Dimitriadis, E

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Cloning of a murine IL‐11 receptor alpha‐chain; requirement for gp130 for high affinity binding and signal transduction by Hilton, D.J., Hilton, A.A., Raicevic, A., Rakar, S., Harrison‐Smith, M., Gough, N.M., Begley, C.G., Metcalf, D., Nicola, N.A., Willson, T.A.

“…An adult mouse liver cDNA library was screened with oligonucleotides corresponding to the conserved WSXWS motif of the haemopoietin receptor family. Using this…”
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Expression cloning of a receptor for human granulocyte‐macrophage colony‐stimulating factor by Gearing, D.P., King, J.A., Gough, N.M., Nicola, N.A.

“…Two cDNA clones encoding a receptor for human granulocyte‐macrophage colony‐stimulating factor (hGM‐CSF‐R) were isolated by expression screening of a library…”
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Suckling defect in mice lacking the soluble haemopoietin receptor NR6 by Alexander, W.S., Rakar, S., Robb, L., Farley, A., Willson, T.A., Zhang, J-G., Hartley, L., Kikuchi, Y., Kojima, T., Nomura, H., Hasegawa, M., Maeda, M., Fabri, L., Jachno, K., Nash, A., Metcalf, D., Nicola, N.A., Hilton, D.J.

“…Cytokines control a variety of cellular responses including proliferation, differentiation, survival and functional activation, via binding to specific…”
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Resolving conflicting signals: cross inhibition of cytokine signaling pathways by Begley, C G, Nicola, N A

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Cross-species receptor binding characteristics of human and mouse leukemia inhibitory factor suggest a complex binding interaction by LAYTON, M. J, LOCK, P, METCALF, D, NICOLA, N. A

“…Leukemia inhibitory factor (LIF) is a pleiotropic cytokine whose activities appear to be mediated through a single heterodimeric receptor complex. Human LIF…”
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PS1446 THE ROLE OF THE THROMBOPOIETIN RECEPTOR (MPL) IN JAK2V617F‐POSITIVE MYELOPLROLIFERATIVE NEOPLASMS by Behrens, K., Viney, E.M., Willson, T.A., Babon, J.J., Nicola, N.A., Alexander, W.S.

“…Background: Constitutive activation of the Jak/Stat signalling pathway is a hallmark of Myeloproliferative Neoplasms (MPN), with 60–90% of patients carrying…”
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Direct Proliferative Actions of Stem Cell Factor on Murine Bone Marrow Cells in vitro: Effects of Combination with Colony-Stimulating Factors by Metcalf, D., Nicola, N. A.

“…Stem cell factor (SCF), the ligand for the c-kit protooncogene product, was able to stimulate blast cell and granulocytic colony formation by precursors from…”
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Resolving Conflicting Signals: Cross Inhibition of Cytokine Signaling Pathways by Begley, C.G., Nicola, N.A.

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Effects of Injected Leukemia Inhibitory Factor on Hematopoietic and Other Tissues in Mice by Metcalf, D., Nicola, N.A., Gearing, D.P.

“…Purified bacterially synthesized recombinant murine leukemia inhibitory factor (LIF) was injected in varying doses for up to 2 weeks into adult DBA/2 and…”
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Functional Analysis of Mature Hematopoietic Cells From Mice Lacking the βc Chain of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor by Scott, C.L., Hughes, D.A., Cary, D., Nicola, N.A., Begley, C.G., Robb, L.

“…Mice with a null mutation of the βc chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors (βc-null…”
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The Clonal Proliferation of Normal Mouse Hematopoietic Cells: Enhancement and Suppression by Colony-Stimulating Factor Combinations by Metcalf, D., Nicola, N.A.

“…Combinations of relatively high concentrations of the four colony-stimulating factors (CSFs) in cultures of normal mouse bone marrow cells stimulated…”
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Leukemia Inhibitory Factor Can Potentiate Murine Megakaryocyte Production In Vitro by Metcalf, D., Hilton, D., Nicola, N.A.

“…Receptors for murine leukemia inhibitory factor (LIF) were demonstrated on immature and mature murine megakaryocytes. LIF alone had no effects in culture on…”
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Residue 21 of human granulocyte‐macrophage colony‐stimulating factor is critical for biological activity and for high but not low affinity binding by Lopez, A.F., Shannon, M.F., Hercus, T., Nicola, N.A., Cambareri, B., Dottore, M., Layton, M.J., Eglinton, L., Vadas, M.A.

“…The functional role of the predicted first alpha‐helix of human granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) was analysed by site‐directed…”
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Effects of Purified Bacterially Synthesized Murine Multi-CSF (IL-3) on Hematopoiesis in Normal Adult Mice by Metcalf, D., Begley, C.G., Johnson, G.R., Nicola, N.A., Lopez, A.F., Williamson, D.J.

“…Normal adult C57BL, BALB/c, and C3H/HeJ mice were injected intraperitoneally three times daily for up to 6 days with 102,000 U (200 ng) per injection of…”
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Specific Binding of Murine Leukemia Inhibitory Factor to Normal and Leukemic Monocytic Cells by Hilton, D. J., Nicola, N. A., Metcalf, D.

“…Leukemia inhibitory factor (LIF), a glycoprotein capable of suppressing the clonogenicity and inducing the differentiation of the murine myeloid leukemia cell…”
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Differentiation commitment in normal hemopoiesis and leukemic transformation by Metcalf, D., Nicola, N. A., Robb, L.

“…Differentiation commitment events are essential for the initiation of hemopoiesis and, in one form or another, occur continuously during adult hemopoiesis. The…”
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Molecular Cloning and Expression of the Human Homologue of the Murine Gene Encoding Myeloid Leukemia-Inhibitory Factor by Gough, Nicholas M., Gearing, David P., King, Julie A., Willson, Tracy A., Hilton, Douglas J., Nicola, Nicos A., Metcalf, Donald

“…A human homologue of the recently cloned murine leukemia-inhibitory factor (LIF) gene was isolated from a genomic library by using the murine cDNA as a…”
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