Search Results - "Nicola, George"

Druggable exosites of the human kino-pocketome by Nicola, George, Kufareva, Irina, Ilatovskiy, Andrey V., Abagyan, Ruben

“…Small molecules binding at any of the multiple regulatory sites on the molecular surface of a protein kinase may stabilize or disrupt the corresponding…”
Get full text

A simple shape characteristic of protein-protein recognition by Nicola, George, Vakser, Ilya A.

“…Motivation: Observation of co-crystallized protein-protein complexes and low-resolution protein-protein docking studies suggest the existence of a…”
Get full text

THE IMPORTANCE OF INTRODUCING MEDICAL LEGISLATION IN THE UNIVERSITY TRAINING PROGRAM FOR STUDENTS by Nicola, George, Gheorghiu, Irina Maria, Scarlatescu, Sanziana, Perlea, Paula

“…The place of medical legislation in the university curriculum remains somehow uncertain and should be identified more clearly. A more robust knowledge base on…”
Get full text

Case selection in dental bleaching by Gheorghiu, Irina-Maria, Perlea, Paula, Scarlatescu, Sanziana, Nicola, George

“…Dental bleaching is a method of treatment for tooth discoloration that uses hydrogen peroxide in various concentrations. For this dental maneuver to be…”
Get full text

Resin composites direct restoration of enamel structural defects – case report by Gheorghiu, Irina-Maria, Scarlatescu, Sanziana, Nicola, George, Iliescu, Alexandru-Andrei, Parlatescu, Ioanina, Suciu, Ioana, Perlea, Paula

“…During dentition development stages, various defects of the dental structures can appear and can be in shape, number, position, structure. The latter primarily…”
Get full text

FREQUENT PROCEDURAL ERRORS AND STRUCTURAL COMPLICATIONS ON ENDODONTICAL TREATED TEETH by Scarlatescu, Sanziana Adina, Gheorghiu, Irina, Nicola, George, Aloul, Andrei O. Al, Perlea, Paula

“…The objectives of root canal treatment are to prevent the apical parodontitis, to heal the acute or cronic apical periodontits and to maintain the results,…”
Get full text

Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition by Chrencik, Jill E., Brooun, Alexei, Recht, Michael I., Nicola, George, Davis, Leila K., Abagyan, Ruben, Widmer, Hans, Pasquale, Elena B., Kuhn, Peter

“…The Eph family of receptor tyrosine kinases has been implicated in tumorigenesis as well as pathological forms of angiogenesis. Understanding how to modulate…”
Get full text

Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor:  A Role for Ser-110 in Deacylation by Nicola, George, Peddi, Sridhar, Stefanova, Miglena, Nicholas, Robert A, Gutheil, William G, Davies, Christopher

“…Penicillin-binding protein 5 (PBP 5) from Escherichia coli is a well-characterized d-alanine carboxypeptidase that serves as a prototypical enzyme to elucidate…”
Get full text

A simple shape characteristic of protein–protein recognition by Nicola, George, Vakser, Ilya A.

Get full text

Complications in children with ventricular assist devices: systematic review and meta-analyses by George, Andrea Nicola, Hsia, Tain-Yen, Schievano, Silvia, Bozkurt, Selim

“…Heart failure is a significant cause of mortality in children with cardiovascular diseases. Treatment of heart failure depends on patients’ symptoms, age, and…”
Get full text

BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology by Gilson, Michael K, Liu, Tiqing, Baitaluk, Michael, Nicola, George, Hwang, Linda, Chong, Jenny

“…BindingDB, www.bindingdb.org, is a publicly accessible database of experimental protein-small molecule interaction data. Its collection of over a million data…”
Get full text

Experimental Roman Minting: Casting Silver-Copper Alloys into a Bronze Mould by Nicola George

“…This paper provides the details of a Roman minting experiment, which used a bronze mould to cast debased silver blanks typical of the third century A.D. The…”
Get full text

Crystal Structure of Wild-type Penicillin-binding Protein 5 from Escherichia coli by Nicholas, Robert A., Krings, Sandra, Tomberg, Joshua, Nicola, George, Davies, Christopher

“…Penicillin-binding protein 5 (PBP 5) of Escherichia coli functions as a d-alanine carboxypeptidase (CPase), cleaving d-alanine from the C terminus of cell wall…”
Get full text

Public Domain Databases for Medicinal Chemistry by Nicola, George, Liu, Tiqing, Gilson, Michael K

Get full text

The endodontic treatment in pregnancy by Gheorghiu, Irina-Maria, Scărlătescu, Sânziana, Mitran, Loredana, Nicola, George, Perlea, Paula, Iliescu, Alexandru A, Mitran, Mihai

Get full text

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics with Escherichia coli Penicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity by Nicola, George, Tomberg, Joshua, Pratt, R. F, Nicholas, Robert A, Davies, Christopher

“…Penicillin-binding proteins (PBPs) are the molecular targets for the widely used β-lactam class of antibiotics, but how these compounds act at the molecular…”
Get full text

BindingDB: A Protein-Ligand Database for Drug Discovery by Nicola, George, Liu, Tiqing, Hwang, Linda, Gilson, Michael

Get full text

The Manufacture of Official Roman Silver Coinage and Blanks between AD193 and AD270 by George, Nicola Elizabeth

“…This thesis addresses the lack of microstructural data for Roman silver coins which has impeded our understanding of the methods used in their manufacture. In…”
Get full text

MANAGING THE RELATIONSHIP WITH THE PRESS IN THE CONTEXT OF MEDICAL MALPRACTICE ACCUSATION by Nicola, G, Gheorghiu, IM, Scarlatescu, S, Constantinescu, FE, Perlea, P

Get full text

Structure-based approaches to antibiotic drug discovery by Nicola, George, Abagyan, Ruben

“…The development of antimicrobials has advanced tremendously over the past century. However, as our production capacity increases, the threat of resistance is…”
Get more information