Search Results - "Nicol, Rebekka"

Signal-Dependent Activation of the MEF2 Transcription Factor by Dissociation from Histone Deacetylases by Lu, Jianrong, McKinsey, Timothy A., Nicol, Rebekka L., Olson, Eric N.

“…Myocyte enhancer factor-2 (MEF2) transcription factors control muscle-specific and growth factor-inducible genes. We show that hypertrophic growth of…”
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Myocyte-Enriched Calcineurin-Interacting Protein, MCIP1, Inhibits Cardiac Hypertrophy in vivo by Rothermel, Beverly A., McKinsey, Timothy A., Vega, Rick B., Nicol, Rebekka L., Mammen, Pradeep, Yang, John, Antos, Christopher L., Shelton, John M., Bassel-Duby, Rhonda, Olson, Eric N., Williams, R. Sanders

“…Signaling events controlled by calcineurin promote cardiac hypertrophy, but the degree to which such pathways are required to transduce the effects of various…”
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Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy by Nicol, Rebekka L., Frey, Norbert, Pearson, Gray, Cobb, Melanie, Richardson, James, Olson, Eric N.

“…Mitogen‐activated protein kinase (MAPK) pathways couple intrinsic and extrinsic signals to hypertrophic growth of cardiomyocytes. The MAPK kinase MEK5…”
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Carbamazepine is an inhibitor of histone deacetylases by Beutler, Andreas S., Li, SiDe, Nicol, Rebekka, Walsh, Martin J.

“…Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and…”
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CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo by Passier, R, Zeng, H, Frey, N, Naya, F J, Nicol, R L, McKinsey, T A, Overbeek, P, Richardson, J A, Grant, S R, Olson, E N

“…Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly,…”
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Transcriptional Repression by v-Ski and c-Ski Mediated by a Specific DNA Binding Site by Nicol, R, Stavnezer, E

“…The Ski oncoprotein has been shown to bind DNA and activate transcription in conjunction with other cellular factors. Because tumor cells or myogenic cells…”
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A domain necessary for the transforming activity of SnoN is required for specific DNA binding, transcriptional repression and interaction with TAFII110 by COHEN, S. B, NICOL, R, STAVNEZER, E

“…sno is a member of the ski oncogene family and shares ski's ability to transform avian fibroblasts and induce muscle differentiation. Ski and Sno are nuclear…”
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A domain necessary for the transforming activity of SnoN is required for specific DNA binding, transcriptional repression and interaction with TAF(II)110 by Cohen, S B, Nicol, R, Stavnezer, E

“…sno is a member of the ski oncogene family and shares ski's ability to transform avian fibroblasts and induce muscle differentiation. Ski and Sno are nuclear…”
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Specific DNA binding and repression of transcription by Ski by Nicol, Rebekka Lynn

“…Although v-ski was originally identified on the basis of its ability to transform chicken embryo fibroblasts in culture, more and more evidence is accumulating…”
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Association of specific DNA binding and transcriptional repression with the transforming and myogenic activities of c-Ski by NICOL, R, GUOXING ZHENG, SUTRAVE, P, FOSTER, D. N, STAVNEZER, E

“…The ski oncogene encodes a transcription factor that induces both transformation and muscle differentiation in avian fibroblasts. The first 304 amino acids of…”
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