Search Results - "Nicol, Lionel"

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction by Henri, Orianne, Pouehe, Chris, Houssari, Mahmoud, Galas, Ludovic, Nicol, Lionel, Edwards-Lévy, Florence, Henry, Jean-Paul, Dumesnil, Anais, Boukhalfa, Inès, Banquet, Sébastien, Schapman, Damien, Thuillez, Christian, Richard, Vincent, Mulder, Paul, Brakenhielm, Ebba

“…BACKGROUND—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic malfunction causes edema. The heart has an extensive lymphatic…”
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Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction by Gueret, Alexandre, Harouki, Najah, Favre, Julie, Galmiche, Guillaume, Nicol, Lionel, Henry, Jean-Paul, Besnier, Marie, Thuillez, Christian, Richard, Vincent, Kolkhof, Peter, Mulder, Paul, Jaisser, Frédéric, Ouvrard-Pascaud, Antoine

“…Mineralocorticoid receptor (MR) antagonists slow down the progression of heart failure after myocardial infarction (MI), but the cell-specific role of MR in…”
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Benefits of the Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone in Metabolic Syndrome-Related Heart Failure with Preserved Ejection Fraction by Lima-Posada, Ixchel, Stephan, Yohan, Soulié, Matthieu, Palacios-Ramirez, Roberto, Bonnard, Benjamin, Nicol, Lionel, Kolkhof, Peter, Jaisser, Frederic, Mulder, Paul

“…The mineralocorticoid receptor (MR) plays an important role in the development of chronic kidney disease (CKD) and associated cardiovascular complications…”
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Myocardial Injury After Ischemia/Reperfusion Is Attenuated By Pharmacological Galectin-3 Inhibition by Ibarrola, Jaime, Matilla, Lara, Martínez-Martínez, Ernesto, Gueret, Alexandre, Fernández-Celis, Amaya, Henry, Jean-Paul, Nicol, Lionel, Jaisser, Frederic, Mulder, Paul, Ouvrard-Pascaud, Antoine, López-Andrés, Natalia

“…Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates…”
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Short‐ and long‐term administration of the non‐steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome‐related cardio‐renal dysfunction by Lachaux, Marianne, Barrera‐Chimal, Jonatan, Nicol, Lionel, Rémy‐Jouet, Isabelle, Renet, Sylvanie, Dumesnil, Anais, Wecker, Didier, Richard, Vincent, Kolkhof, Peter, Jaisser, Frederic, Ouvrard‐Pascaud, Antoine, Mulder, Paul

“…Aim To determine whether non‐steroidal mineralocorticoid receptor (MR) antagonists oppose metabolic syndrome‐related end‐organ, i.e. cardiac, damage. Materials…”
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Magnetic resonance colonography assessment of acute trinitrobenzene sulfonic acid colitis in pre-pubertal rats by Dupont-Lucas, Claire, Marion-Letellier, Rachel, Pala, Mathilde, Guerin, Charlène, Bôle-Feysot, Christine, Salameh, Emmeline, Goichon, Alexis, Nicol, Lionel, Aziz, Moutaz, Savoye-Collet, Céline, Savoye, Guillaume

“…Pre-pubertal murine models of acute colitis are lacking. Magnetic resonance colonography (MRC) is a promising minimally invasive tool to assess colitis. We…”
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Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Diastolic Dysfunction in Preclinical Nondiabetic Chronic Kidney Disease by Lima Posada, Ixchel, Soulié, Matthieu, Stephan, Yohan, Palacios Ramirez, Roberto, Bonnard, Benjamin, Nicol, Lionel, Pitt, Bertram, Kolkhof, Peter, Mulder, Paul, Jaisser, Frederic

“…The mineralocorticoid receptor plays a significant role in the development of chronic kidney disease (CKD) and associated cardiovascular complications. Classic…”
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Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice by Besnier, Marie, Galaup, Ariane, Nicol, Lionel, Henry, Jean‐Paul, Coquerel, David, Gueret, Alexandre, Mulder, Paul, Brakenhielm, Ebba, Thuillez, Christian, Germain, Stéphane, Richard, Vincent, Ouvrard‐Pascaud, Antoine

“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure by Harouki, Najah, BS, Nicol, Lionel, PhD, Remy-Jouet, Isabelle, PhD, Henry, Jean-Paul, BS, Dumesnil, Anais, BS, Lejeune, Annie, BS, Renet, Sylvanie, BS, Golding, Francesca, BS, Djerada, Zoubir, PhD, Wecker, Didier, PhD, Bolduc, Virginie, PhD, Bouly, Muriel, PhD, Roussel, Jerome, PhD, Richard, Vincent, PhD, Mulder, Paul, PhD

“…Visual Abstract…”
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Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure by BANQUET, Sebastien, GOMEZ, Elodie, YIHAI CAO, THUILLEZ, Christian, MULDER, Paul, RICHARD, Vincent, BRAKENHIELM, Ebba, NICOL, Lionel, EDWARDS-LEVY, Florence, HENRY, Jean-Paul, CAO, Renhai, SCHAPMAN, Damien, DAUTREAUX, Brigitte, LALLEMAND, Francoise, BAUER, Fabrice

“…Therapeutic angiogenesis is a promising approach for the treatment of cardiovascular diseases, including myocardial infarction and chronic heart failure. We…”
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Repetitive Trans Spinal Magnetic Stimulation Improves Functional Recovery and Tissue Repair in Contusive and Penetrating Spinal Cord Injury Models in Rats by Robac, Amandine, Neveu, Pauline, Hugede, Alizée, Garrido, Elisabeth, Nicol, Lionel, Delarue, Quentin, Guérout, Nicolas

“…Spinal cord injury (SCI) is an incurable condition in which the brain is disconnected partially or completely from the periphery. Mainly, SCIs are traumatic…”
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Selective Vascular Endothelial Protection Reduces Cardiac Dysfunction in Chronic Heart Failure by Maupoint, Julie, Besnier, Marie, Gomez, Elodie, Bouhzam, Najime, Henry, Jean-Paul, Boyer, Olivier, Nicol, Lionel, Mulder, Paul, Martinet, Jérémie, Richard, Vincent

“…Chronic heart failure (CHF) induces endothelial dysfunction in part because of decreased nitric oxide (NO(·)) production, but the direct link between…”
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A polymeric diet rich in transforming growth factor beta 2 does not reduce inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal rats by Dupont-Lucas, Claire, Marion-Letellier, Rachel, Pala, Mathilde, Guerin, Charlène, Amamou, Asma, Jarbeau, Marine, Bôle-Feysot, Christine, Nicol, Lionel, David, Amelyne, Aziz, Moutaz, Colasse, Elodie, Savoye-Collet, Céline, Savoye, Guillaume

“…Pediatric Crohn's disease is characterized by a higher incidence of complicated phenotypes. Murine models help to better understand the dynamic process of…”
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Magnetic resonance colonography for fibrosis assessment in rats with chronic colitis by Melchior, Chloé, Loeuillard, Emilien, Marion-Letellier, Rachel, Nicol, Lionel, Mulder, Paul, Guerin, Charlène, Bôle-Feysot, Christine, Aziz, Moutaz, Déchelotte, Pierre, Vera, Pierre, Savoye, Guillaume, Savoye-Collet, Céline

“…Magnetic resonance colonography (MRC) has been developed to assess inflammatory bowel diseases. We aimed to assess the feasibility of MRC in rats with…”
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Short‐and long‐term administration of imeglimin counters cardiorenal dysfunction in a rat model of metabolic syndrome by Lachaux, Marianne, Soulié, Matthieu, Hamzaoui, Mouad, Bailly, Anaëlle, Nicol, Lionel, Rémy‐Jouet, Isabelle, Renet, Sylvanie, Vendeville, Cathy, Gluais‐Dagorn, Pascale, Hallakou‐Bozec, Sophie, Monteil, Christelle, Richard, Vincent, Mulder, Paul

“…Introduction Imeglimin, a glucose‐lowering agent targeting mitochondrial bioenergetics, decreases reactive oxygen species (ROS) overproduction and improves…”
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Inhibition of Soluble Epoxide Hydrolase Does Not Promote or Aggravate Pulmonary Hypertension in Rats by Leuillier, Matthieu, Platel, Valentin, Tu, Ly, Feugray, Guillaume, Thuillet, Raphaël, Groussard, Déborah, Messaoudi, Hind, Ottaviani, Mina, Chelgham, Mustapha, Nicol, Lionel, Mulder, Paul, Humbert, Marc, Richard, Vincent, Morisseau, Christophe, Brunel, Valéry, Duflot, Thomas, Guignabert, Christophe, Bellien, Jérémy

“…Inhibitors of soluble epoxide hydrolase (sEH), which catalyzes the hydrolysis of various natural epoxides to their corresponding diols, present an opportunity…”
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Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice by Pieronne‐Deperrois, Marie, Guéret, Alexandre, Djerada, Zoubir, Crochemore, Clément, Harouki, Najah, Henry, Jean‐Paul, Dumesnil, Anaïs, Larchevêque, Marine, Rego, Jean‐Claude, Rego, Jean‐Luc, Nicol, Lionel, Richard, Vincent, Jaisser, Frédéric, Kolkhof, Peter, Mulder, Paul, Monteil, Christelle, Ouvrard‐Pascaud, Antoine

“…Aims In post‐menopausal women, incidence of heart failure with preserved ejection fraction is higher than in men. Hormonal replacement therapies did not…”
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Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction by Peschanski, Nicolas, Harouki, Najah, Soulie, Matthieu, Lachaux, Marianne, Nicol, Lionel, Remy‐Jouet, Isabelle, Henry, Jean‐Paul, Dumesnil, Anais, Renet, Sylvanie, Fougerousse, Françoise, Brakenhielm, Ebba, Ouvrard‐Pascaud, Antoine, Thuillez, Christian, Richard, Vincent, Roussel, Jérôme, Mulder, Paul

“…Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by…”
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386-P: Chronic Treatment with the Direct AMPK Activator PXL770 Improves Cardiac, Vascular, and Renal Function in Rodents with Diabetes-Related Cardiorenal Disease by STEPHAN, YOHAN, SOULIÉ, MATTHIEU, NICOL, LIONEL, GLUAIS-DAGORN, PASCALE, HALLAKOU-BOZEC, SOPHIE, MULDER, PAUL

“…Introduction: PXL770 is a direct AMP kinase activator. In models of T2DM and NASH, PXL770 improves hyperglycemia and dyslipidemia and reduces: steatosis,…”
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The Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Left Ventricular Function in Preclinical CKD: FR-PO998 by Jaisser, Frederic, Posada, Ixchel Q. Lima, Stephan, Yohan, Soulié, Matthieu, Ramirez, Roberto Palacios, Bonnard, Benjamin, Nicol, Lionel, Kolkhof, Peter, Mulder, Paul

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