Search Results - "Nicol, L"

Potential Mechanisms Underlying Centralized Pain and Emerging Therapeutic Interventions by Eller-Smith, Olivia C, Nicol, Andrea L, Christianson, Julie A

“…Centralized pain syndromes are associated with changes within the central nervous system that amplify peripheral input and/or generate the perception of pain…”
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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing by Gerlinger, Marco, Horswell, Stuart, Larkin, James, Rowan, Andrew J, Salm, Max P, Varela, Ignacio, Fisher, Rosalie, McGranahan, Nicholas, Matthews, Nicholas, Santos, Claudio R, Martinez, Pierre, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Spencer-Dene, Bradley, Gulati, Sakshi, Bates, Paul A, Stamp, Gordon, Pickering, Lisa, Gore, Martin, Nicol, David L, Hazell, Steven, Futreal, P Andrew, Stewart, Aengus, Swanton, Charles

“…Charles Swanton and colleagues used multiregion exome sequencing to study the evolutionary histories of ten clear cell renal cell carcinomas. They observed…”
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Cross-sectional and longitudinal analysis of bone age maturation during peri-pubertal growth in children with type I, III and IV osteogenesis imperfecta by Nicol, L.E., Baines, H., Koike, S., Liu, W., Orwoll, E.

“…Osteogenesis imperfecta (OI)is a rare genetically heterogeneous disorder caused by changes in the expression or processing of type I collagen. Clinical…”
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Benefit of combination therapy with dapagliflozin and eplerenone on cardiac function and fibrosis in rats with non-diabetic chronic kidney disease by Soulié, M., Stephan, Y., Durand, M., Lima-Posada, I., Palacios-Ramírez, R., Nicol, L., Lopez-Andres, N., Mulder, P., Jaisser, F.

“…Patients with chronic kidney disease (CKD) are at a high risk of cardiovascular (CV) complications. In these patients, sodium-glucose cotransporter-2…”
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How riparian and floodplain restoration modify the effects of increasing temperature on adult salmon spawner abundance in the Chehalis River, WA by Fogel, Caleb B, Nicol, Colin L, Jorgensen, Jeffrey C, Beechie, Timothy J, Timpane-Padgham, Britta, Kiffney, Peter, Seixas, Gustav, Winkowski, John

“…Stream temperatures in the Pacific Northwest are projected to increase with climate change, placing additional stress on cold-water salmonids. We modeled the…”
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Alterations of a serum marker of collagen X in growing children with osteogenesis imperfecta by Nicol, L.E., Coghlan, R.F., Cuthbertson, D., Nagamani, Sandesh C.S., Lee, B., Olney, R.C., Horton, W., Orwoll, E.

“…Abnormalities in the structure and/or processing of type I collagen cause osteogenesis imperfecta and result in bone fragility, abnormal bone growth and short…”
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The Association Between a History of Lifetime Traumatic Events and Pain Severity, Physical Function, and Affective Distress in Patients With Chronic Pain by Nicol, Andrea L, Sieberg, Christine B, Clauw, Daniel J, Hassett, Afton L, Moser, Stephanie E, Brummett, Chad M

“…Evidence suggests that pain patients who report lifetime abuse experience greater psychological distress, have more severe pain and other physical symptoms,…”
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Detection of Human Papillomavirus-16 in Fine-Needle Aspirates to Determine Tumor Origin in Patients with Metastatic Squamous Cell Carcinoma of the Head and Neck by BEGUM, Shahnaz, GILLISON, Maura L, NICOL, Theresa L, WESTRA, William H

“…Purpose: Patients with head and neck squamous cell carcinoma (HNSCC) often clinically present with metastases to regional lymph nodes. Fine-needle aspiration…”
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Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy by Nicol, Rebekka L., Frey, Norbert, Pearson, Gray, Cobb, Melanie, Richardson, James, Olson, Eric N.

“…Mitogen‐activated protein kinase (MAPK) pathways couple intrinsic and extrinsic signals to hypertrophic growth of cardiomyocytes. The MAPK kinase MEK5…”
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Alternatives to Opioids in the Pharmacologic Management of Chronic Pain Syndromes: A Narrative Review of Randomized, Controlled, and Blinded Clinical Trials by Nicol, Andrea L., Hurley, Robert W., Benzon, Honorio T.

“…Chronic pain exerts a tremendous burden on individuals and societies. If one views chronic pain as a single disease entity, then it is the most common and…”
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Signal-Dependent Activation of the MEF2 Transcription Factor by Dissociation from Histone Deacetylases by Lu, Jianrong, McKinsey, Timothy A., Nicol, Rebekka L., Olson, Eric N.

“…Myocyte enhancer factor-2 (MEF2) transcription factors control muscle-specific and growth factor-inducible genes. We show that hypertrophic growth of…”
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Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates by Nicol, L E, Grant, W F, Comstock, S M, Nguyen, M L, Smith, M S, Grove, K L, Marks, D L

“…Chronic high caloric intake has contributed to the increased prevalence of pediatric obesity and related morbidities. Most overweight or obese children,…”
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Outcomes of Postchemotherapy Retroperitoneal Lymph Node Dissection from a High-volume UK Centre Compared with a National Data Set by Pearce, Adam Kieran, Manson-Bahr, David, Reid, Alison, Huddart, Robert, Mayer, Erik, Nicol, David L.

“…Retroperitoneal lymph node dissection (RPLND) is essential for the treatment of metastatic germ cell tumours of the testis. Recommendations on the referral and…”
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An Individualized Exercise Intervention for People with Multiple Myeloma-Study Protocol of a Randomized Waitlist-Controlled Trial by Nicol, Jennifer L, Woodrow, Carmel, Cunningham, Brent J, Mollee, Peter, Weber, Nicholas, Smith, Michelle D, Nicol, Andrew J, Gordon, Louisa G, Hill, Michelle M, Skinner, Tina L

“…People with multiple myeloma (MM) are second only to people with lung cancer for the poorest reported health-related quality of life (HRQoL) of all cancer…”
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Paratesticular Sarcoma: Typical Presentation, Imaging Features and Clinical Challenges by ap Dafydd, Derfel, MRCP FRCR, Messiou, Christina, MD MRCP FRCR, Thway, Khin, MD FRCPath, Strauss, Dirk C, MMed(Surg), FCS(SA), FRCS(Gen), Nicol, David L, MBBS FRACS, Moskovic, Eleanor, FRCP FRCR

“…Abstract Objective To describe the major imaging features, together with clinical data, of paratesticular sarcomas. Methods A retrospective analysis was…”
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Birthweight and natural deaths in a remote Australian Aboriginal community by Hoy, Wendy E, Nicol, Jennifer L

“…Objectives: To describe associations between birthweight and infant, child and early adult mortality from natural causes in a remote Australian Aboriginal…”
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Value of magnetic resonance imaging for evaluating muscle inflammation: insights from a new mouse model of myositis by Bourdenet, G., Dubourg, B., Nicol, L., Mulder, P., Martinet, J., Allenbach, Y., Boitard, C., Boyer, O.

“…Inflammatory myopathies or myositides represent a group of severe skeletal muscle diseases characterized by muscle weakness, elevation of serum creatine kinase…”
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Myocyte-Enriched Calcineurin-Interacting Protein, MCIP1, Inhibits Cardiac Hypertrophy in vivo by Rothermel, Beverly A., McKinsey, Timothy A., Vega, Rick B., Nicol, Rebekka L., Mammen, Pradeep, Yang, John, Antos, Christopher L., Shelton, John M., Bassel-Duby, Rhonda, Olson, Eric N., Williams, R. Sanders

“…Signaling events controlled by calcineurin promote cardiac hypertrophy, but the degree to which such pathways are required to transduce the effects of various…”
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CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo by Passier, R, Zeng, H, Frey, N, Naya, F J, Nicol, R L, McKinsey, T A, Overbeek, P, Richardson, J A, Grant, S R, Olson, E N

“…Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly,…”
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Assessment of endothelial damage and cardiac injury in a mouse model mimicking thrombotic thrombocytopenic purpura by Le Besnerais, M., Favre, J., Denis, C. V., Mulder, P., Martinet, J., Nicol, L., Levesque, H., Veyradier, A., Kopić, A., Motto, D. G., Coppo, P., Richard, V., Benhamou, Y.

“…Essentials Endothelial injury is thought to be a key event in thrombotic thrombocytopenic purpura (TTP). Endothelial and cardiac damages were assessed in a…”
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