Search Results - "Nicod, Laurent P"
-
1
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
Published in Nature medicine (01-02-2014)“…Dietary fibers are metabolized by the gut microbiota into short-chain fatty acids (SCFAs) and have protective effects in inflammatory bowel disease. Here…”
Get full text
Journal Article -
2
Microbiota Promotes Chronic Pulmonary Inflammation by Enhancing IL-17A and Autoantibodies
Published in American journal of respiratory and critical care medicine (01-05-2016)“…Changes in the pulmonary microbiota are associated with progressive respiratory diseases including chronic obstructive pulmonary disease (COPD). Whether there…”
Get full text
Journal Article -
3
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation
Published in Mucosal immunology (01-08-2022)“…Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function is linked with enhanced allergen…”
Get full text
Journal Article -
4
Airway Microbiota Determines Innate Cell Inflammatory or Tissue Remodeling Profiles in Lung Transplantation
Published in American journal of respiratory and critical care medicine (15-11-2016)“…In lung transplant recipients, long-term graft survival relies on the control of inflammation and tissue remodeling to maintain graft functionality and avoid…”
Get full text
Journal Article -
5
A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
Published in Nature communications (09-04-2021)“…There is accumulating evidence that the lower airway microbiota impacts lung health. However, the link between microbial community composition and lung…”
Get full text
Journal Article -
6
The Airway Microbiome and Disease
Published in Chest (01-08-2013)“…Although traditionally thought to be sterile, accumulating evidence now supports the concept that our airways harbor a microbiome. Thus far, studies have…”
Get full text
Journal Article -
7
Immunotherapy-Induced Airway Disease: A New Pattern of Lung Toxicity of Immune Checkpoint Inhibitors
Published in Respiration (01-02-2020)“…Immune checkpoint inhibitors (ICIs) have been shown to improve overall and progression-free survival in various cancers but have been associated with various…”
Get more information
Journal Article -
8
GLI 2012 equations define few spirometric anomalies in the general population: the PneumoLaus study
Published in Respiratory research (13-12-2018)“…Reduced lung function predicts increased mortality, but its prevalence may vary depending on definition considered, use of bronchodilation and applied…”
Get full text
Journal Article -
9
Targeting IL-1β and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation
Published in PloS one (11-06-2014)“…For patients with chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), exacerbations are life-threatening events causing acute…”
Get full text
Journal Article -
10
Nitric oxide sustains IL-1β expression in human dendritic cells enhancing their capacity to induce IL-17-producing T-cells
Published in PloS one (08-04-2015)“…The role played by lung dendritic cells (DCs) which are influenced by external antigens and by their redox state in controlling inflammation is unclear. We…”
Get full text
Journal Article -
11
DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells
Published in The Journal of experimental medicine (06-01-2003)“…Early interactions between lung dendritic cells (LDCs) and Mycobacterium tuberculosis, the etiological agent of tuberculosis, are thought to be critical for…”
Get full text
Journal Article -
12
Immunology taught by lung dendritic cells
Published in Swiss medical weekly (04-04-2009)“…Dendritic cells (DCs) are leukocytes specialised in the uptake, processing, and presentation of antigen and fundamental in regulating both innate and adaptive…”
Get full text
Journal Article -
13
A 3-Step Therapeutic Strategy for Severe Alveolar Proteinosis
Published in The Annals of thoracic surgery (01-04-2015)“…Pulmonary alveolar proteinosis (PAP) is characterized by accumulation of lipoproteinaceous material in the terminal airways. Whole lung lavage (WLL) remains…”
Get full text
Journal Article -
14
Radial Ultrasound-Assisted Transbronchial Biopsy: A New Diagnostic Approach for Non-Resolving Pulmonary Infiltrates in Neutropenic Hemato-Oncological Patients
Published in Lung (01-12-2016)“…The role of radial-endobronchial ultrasound (R-EBUS) assisted transbronchial biopsy (TBB) for the diagnosis of peripheral pulmonary lesions is well…”
Get full text
Journal Article -
15
Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
Published in Immunity (Cambridge, Mass.) (15-05-2018)“…Dietary fiber protects against chronic inflammatory diseases by dampening immune responses through short-chain fatty acids (SCFAs). Here we examined the effect…”
Get full text
Journal Article -
16
Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/ FLT3 Monocytes That Promote Allogeneic Th17 Differentiation
Published in Frontiers in immunology (25-04-2017)“…Little is known about monocyte differentiation in the lung mucosal environment and about how the epithelium shapes monocyte function. We studied the role of…”
Get full text
Journal Article -
17
Lung microbiota promotes tolerance to allergens in neonates via PD-L1
Published in Nature medicine (01-06-2014)“…The immune system matures during the neonatal period and is influenced by environmental factors. Benjamin J. Marsland and his colleagues show that the lung is…”
Get full text
Journal Article -
18
Late Major Hemoptysis After Lung Volume Reduction With Coils Induced by Dual Antiaggregation Therapy
Published in The Annals of thoracic surgery (01-02-2016)“…Lung-volume reduction using coils is an effective and safe treatment for selected patients presenting severe emphysema and hyperinflation. Most complications…”
Get full text
Journal Article -
19
Early-Life Formation of the Microbial and Immunological Environment of the Human Airways
Published in Cell host & microbe (12-12-2018)“…Crosstalk between immune cells and the microbiota in mucosal tissues can set an individual on a trajectory toward health or disease. Little is known about…”
Get full text
Journal Article -
20
Respiratory viruses and severe lower respiratory tract complications in hospitalized patients
Published in Chest (01-03-2004)“…Acute respiratory viral infections are generally self-limited in healthy subjects but can lead to severe complications in immunocompromised hosts. We report…”
Get more information
Journal Article