Search Results - "Nickson, Caleb"

Phosphate derivatives of AZT display enhanced selectivity of action against HIV1 by comparison to the parent nucleoside by McGuigan, Christopher, Nickson, Caleb, Petrik, Juraj, Karpas, Abraham

“…Novel phosphate derivatives of the anti-HIV nucleoside analogue AZT have been prepared by phosphorochloridate chemistry. In particular, phosphates carrying…”
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Synthesis and evaluation of novel anti H.I.V. nucleotides by Nickson, Caleb

“…A wide variety of nucleosides have been shown to inhibit human immunodeficiency virus (HIV) which is generally believed to be the causative agent of the…”
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Nucleoside analogues previously found to be inactive against HIV may be activated by simple chemical phosphorylation by McGuigan, Christopher, Kinchington, Derek, Wang, Meng Fang, Nicholls, Simon R., Nickson, Caleb, Galpin, Sarah, Jeffries, Donald J., O'Connor, Timothy J.

“…Nucleoside analogues previously found to be inactive against the human immunodeficiency virus (HIV) may be activated by simple chemical derivatisation. As part…”
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Synthesis and anti-HIV activity of some novel lactyl and glycolyl phosphate derivatives by McGuigan, C, Nickson, C, O'Connor, T J, Kinchington, D

“…Novel phosphate triester derivatives of 3'-acetylthymidine, and of the anti-HIV nucleoside analogue AZT have been prepared by phosphorochloridate chemistry…”
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