Search Results - "Nickolas, Thomas L."

Management of Osteoporosis in CKD by Khairallah, Pascale, Nickolas, Thomas L

“…CKD mineral and bone disease is a common complication of kidney disease, and it affects the majority of patients with moderate to severe CKD. Recently,…”
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KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) by Isakova, Tamara, Nickolas, Thomas L., Denburg, Michelle, Yarlagadda, Sri, Weiner, Daniel E., Gutiérrez, Orlando M., Bansal, Vinod, Rosas, Sylvia E., Nigwekar, Sagar, Yee, Jerry, Kramer, Holly

“…Chronic kidney disease–mineral and bone disorder (CKD-MBD) encompasses laboratory and bone abnormalities and vascular calcification and has deleterious effects…”
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Relationship between moderate to severe kidney disease and hip fracture in the United States by NICKOLAS, Thomas L, MCMAHON, Donald J, SHANE, Elizabeth

“…People with ESRD are at a high risk for hip fracture. However, the effect of moderate to severe chronic kidney disease (CKD) on hip fracture risk has not been…”
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Vitamin K and Osteoporosis by Fusaro, Maria, Cianciolo, Giuseppe, Brandi, Maria Luisa, Ferrari, Serge, Nickolas, Thomas L, Tripepi, Giovanni, Plebani, Mario, Zaninotto, Martina, Iervasi, Giorgio, La Manna, Gaetano, Gallieni, Maurizio, Vettor, Roberto, Aghi, Andrea, Gasperoni, Lorenzo, Giannini, Sandro, Sella, Stefania, M Cheung, Angela

“…Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin K dependent proteins. Beyond its well-known effects on blood…”
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Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase-Associated Lipocalin for Diagnosing Acute Kidney Injury by NICKOLAS, Thomas L, O'ROURKE, Matthew J, DEVARAJAN, Prasad, BARASCH, Jonathan, JUN YANG, SISE, Meghan E, CANETTA, Pietro A, BARASCH, Nicholas, BUCHEN, Charles, KHAN, Faris, MORI, Kiyoshi, GIGLIO, James

“…A single serum creatinine measurement cannot distinguish acute kidney injury from chronic kidney disease or prerenal azotemia. To test the sensitivity and…”
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Chronic kidney disease and bone fracture: a growing concern by Nickolas, Thomas L., Leonard, Mary B., Shane, Elizabeth

“…Susceptibility to fracture is increased across the spectrum of chronic kidney disease (CKD). Moreover, fracture in patients with end-stage kidney disease…”
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Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes by Singer, Eugenia, Elger, Antje, Elitok, Saban, Kettritz, Ralph, Nickolas, Thomas L., Barasch, Jonathan, Luft, Friedrich C., Schmidt-Ott, Kai M.

“…In established acute kidney injury (AKI), serum creatinine poorly differentiates prerenal from intrinsic AKI. In this study, we tested whether urinary…”
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Bone Quality in Chronic Kidney Disease: Definitions and Diagnostics by McNerny, Erin M. B., Nickolas, Thomas L.

“…Purpose of Review In this paper, we review the epidemiology, diagnosis, and pathogenesis of fractures and renal osteodystrophy. Recent Findings The role of…”
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Effect of Advanced Glycation End‐Products (AGE) Lowering Drug ALT‐711 on Biochemical, Vascular, and Bone Parameters in a Rat Model of CKD‐MBD by Chen, Neal X, Srinivasan, Shruthi, O'Neill, Kalisha, Nickolas, Thomas L, Wallace, Joseph M, Allen, Matthew R, Metzger, Corinne E, Creecy, Amy, Avin, Keith G, Moe, Sharon M

“…ABSTRACT Chronic kidney disease–mineral bone disorder (CKD‐MBD) is a systemic disorder that affects blood measures of bone and mineral homeostasis, vascular…”
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The association between a Mediterranean-style diet and kidney function in the Northern Manhattan Study cohort by Khatri, Minesh, Moon, Yeseon P, Scarmeas, Nikolaos, Gu, Yian, Gardener, Hannah, Cheung, Ken, Wright, Clinton B, Sacco, Ralph L, Nickolas, Thomas L, Elkind, Mitchell S V

“…Various dietary strategies have been investigated to slow kidney function decline. However, it is unknown whether a Mediterranean diet, which has been…”
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Biomarkers in acute and chronic kidney disease by Nickolas, Thomas L, Barasch, Jonathan, Devarajan, Prasad

“…PURPOSE OF REVIEWThe paucity of early, predictive, noninvasive biomarkers has impaired our ability to institute potentially effective therapies for acute…”
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Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts by Krevvata, Maria, Silva, Barbara C., Manavalan, John S., Galan-Diez, Marta, Kode, Aruna, Matthews, Brya Grace, Park, David, Zhang, Chiyuan A., Galili, Naomi, Nickolas, Thomas L., Dempster, David W., Dougall, William, Teruya-Feldstein, Julie, Economides, Aris N., Kalajzic, Ivo, Raza, Azra, Berman, Ellin, Mukherjee, Siddhartha, Bhagat, Govind, Kousteni, Stavroula

“…The bone marrow niche is thought to act as a permissive microenvironment required for emergence or progression of hematologic cancers. We hypothesized that…”
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Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy by Martinez-Calle, Marta, Courbon, Guillaume, Hunt-Tobey, Bridget, Francis, Connor, Spindler, Jadeah, Wang, Xueyan, Dos Reis, Luciene M, Martins, Carolina Sw, Salusky, Isidro B, Malluche, Hartmut, Nickolas, Thomas L, Moyses, Rosa Ma, Martin, Aline, David, Valentin

“…Renal osteodystrophy (ROD) is a disorder of bone metabolism that affects virtually all patients with chronic kidney disease (CKD) and is associated with…”
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Does NGAL reduce costs? A cost analysis of urine NGAL (uNGAL) & serum creatinine (sCr) for acute kidney injury (AKI) diagnosis by Parikh, Amay, Rizzo, John A, Canetta, Pietro, Forster, Catherine, Sise, Meghan, Maarouf, Omar, Singer, Eugenia, Elger, Antje, Elitok, Saban, Schmidt-Ott, Kai, Barasch, Jonathon, Nickolas, Thomas L

“…Urine neutrophil gelatinase-associated lipocalin (uNGAL) is a sensitive and specific diagnostic test for acute kidney injury (AKI) in the Emergency Department…”
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Discriminants of Prevalent Fractures in Chronic Kidney Disease by NICKOLAS, Thomas L, CREMERS, Serge, BOUTROY, Stephanie, STARON, Ronald B, LEONARD, Mary B, MCMAHON, Donald J, DWORAKOWSKI, Elzbieta, SHANE, Elizabeth, ZHANG, Amy, THOMAS, Valeri, STEIN, Emily, COHEN, Adi, CHAUNCEY, Ryan, NIKKEL, Lucas, YIN, Michael T, LIU, Xiaowei S

“…Patients with chronic kidney disease (CKD) have higher rates of fracture than the general population. Increased bone remodeling, leading to microarchitectural…”
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PTH(1–84) administration reverses abnormal bone‐remodeling dynamics and structure in hypoparathyroidism by Rubin, Mishaela R, Dempster, David W, Sliney Jr, James, Zhou, Hua, Nickolas, Thomas L, Stein, Emily M, Dworakowski, Elzbieta, Dellabadia, Maryann, Ives, Rebecca, McMahon, Donald J, Zhang, Chiyuan, Silverberg, Shonni J, Shane, Elizabeth, Cremers, Serge, Bilezikian, John P

“…Hypoparathyroidism is associated with abnormal structural and dynamic skeletal properties. We hypothesized that parathyroid hormone(1–84) [PTH(1–84)] treatment…”
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Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study by Cohen, Adi, Stein, Emily M, Recker, Robert. R, Lappe, Joan M, Dempster, David W, Zhou, Hua, Cremers, Serge, McMahon, Donald J, Nickolas, Thomas L, Müller, Ralph, Zwahlen, Alexander, Young, Polly, Stubby, Julie, Shane, Elizabeth

“…Context: Premenopausal women with idiopathic osteoporosis (IOP) have abnormal cortical and trabecular bone microarchitecture. Objective: The purpose of this…”
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Vitamin K and Kidney Transplantation by Fusaro, Maria, Cosmai, Laura, Evenepoel, Pieter, Nickolas, Thomas L, Cheung, Angela M, Aghi, Andrea, Tripepi, Giovanni, Plebani, Mario, Iervasi, Giorgio, Vettor, Roberto, Zaninotto, Martina, Ravera, Maura, Foramitti, Marina, Giannini, Sandro, Sella, Stefania, Gallieni, Maurizio

“…The assessment of the vitamin K status and its effects on clinical outcomes in kidney transplantation (KT) patients has sparked interest, but it is still…”
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Treating Osteoporosis with Denosumab in Patients on Hemodialysis: The Good, the Bad, and the Ugly by Nickolas, Thomas L

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AKI: A Path Forward by Bonventre, Joseph V, Basile, David, Liu, Kathleen D, McKay, Dianne, Molitoris, Bruce A, Nath, Karl A, Nickolas, Thomas L, Okusa, Mark D, Palevsky, Paul M, Schnellmann, Rick, Rys-Sikora, Krystyna, Kimmel, Paul L, Star, Robert A

“…The Kidney Research National Dialogue, supported by the National Institute of Diabetes and Digestive and Kidney Diseases, asked the scientific community to…”
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