Search Results - "Nicklin, J."

Addressing uncertainty in adaptation planning for agriculture by Vermeulen, Sonja J., Challinor, Andrew J., Thornton, Philip K., Campbell, Bruce M., Eriyagama, Nishadi, Vervoort, Joost M., Kinyangi, James, Jarvis, Andy, Läderach, Peter, Ramirez-Villegas, Julian, Nicklin, Kathryn J., Hawkins, Ed, Smith, Daniel R.

“…We present a framework for prioritizing adaptation approaches at a range of timeframes. The framework is illustrated by four case studies from developing…”
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High SARS-CoV-2 incidence and asymptomatic fraction during Delta and Omicron BA.1 waves in The Gambia by Jarju, Sheikh, Wenlock, Rhys D., Danso, Madikoi, Jobe, Dawda, Jagne, Ya Jankey, Darboe, Alansana, Kumado, Michelle, Jallow, Yusupha, Touray, Mamlie, Ceesay, Ebrima A., Gaye, Hoja, Gaye, Biran, Tunkara, Abdoulie, Kandeh, Sheriff, Gomes, Marie, Sylva, Ellen Lena, Toure, Fatoumata, Hornsby, Hailey, Lindsey, Benjamin B., Nicklin, Martin J., Sayers, Jon R., Sesay, Abdul K., Kucharski, Adam, Hodgson, David, Kampmann, Beate, de Silva, Thushan I.

“…Little is known about SARS-CoV-2 infection risk in African countries with high levels of infection-driven immunity and low vaccine coverage. We conducted a…”
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Analysis of clinical decision-making in multi-disciplinary cancer teams by Blazeby, J. M., Wilson, L., Metcalfe, C., Nicklin, J., English, R., Donovan, J. L.

“…Management decisions for patients with cancer are frequently taken within the context of a multi-disciplinary team (MDT). There is little known, however, about…”
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Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes by Sharaf, Nazar, Nicklin, Martin J., di Giovine, Francesco S.

“…•IL1A, IL1B and IL1F7 promoters come in close proximity in LPS-stimulated human monocytes.•These genes are likely transcribed by the same transcription…”
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ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin by Partridge, Lynda J., Urwin, Lucy, Nicklin, Martin J. H., James, David C., Green, Luke R., Monk, Peter N.

“…Coronaviruses such as SARS-CoV-2, which is responsible for COVID-19, depend on virus spike protein binding to host cell receptors to cause infection. The…”
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Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages by MARRIOTT, Helen M, GASCOYNE, Kate A, DOCKRELL, David H, GOWDA, Ravi, GEARY, Ian, NICKLIN, Martin J. H, LANNELLI, Francesco, POZZI, Gianni, MITCHELL, Timothy J, WHYTE, Moira K. B, SABROE, Ian

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Impact of Parameterized Convection on the Simulation of Crop Processes by Garcia-Carreras, L., Challinor, A. J., Parkes, B. J., Birch, C. E., Nicklin, K. J., Parker, D. J.

“…Global climate and weather models are a key tool for the prediction of future crop productivity, but they all rely on parameterizations of atmospheric…”
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Feasibility RCT of definitive chemoradiotherapy or chemotherapy and surgery for oesophageal squamous cell cancer by Blazeby, J M, Strong, S, Donovan, J L, Wilson, C, Hollingworth, W, Crosby, T, Nicklin, J, Falk, S J, Barham, C P, Hollowood, A D, Streets, C G, Titcomb, D, Krysztopik, R, Griffin, S M, Brookes, S T

“…Background: The optimal treatment for localised oesophageal squamous cell carcinoma (SCC) is uncertain. We assessed the feasibility of an RCT comparing…”
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Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis by Mohanty, Sindhu T, Kottam, Lucksy, Gambardella, Alessandra, Nicklin, Martin J, Coulton, Les, Hughes, David, Wilson, Anthony G, Croucher, Peter I, Bellantuono, Ilaria

“…Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily involving the synovium. Evidence in recent years has suggested that the bone…”
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Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy by Williams, Daniel M., Hornsby, Hailey R., Shehata, Ola M., Brown, Rebecca, Gallis, Marta, Meardon, Naomi, Newman, Thomas A.H., Plowright, Megan, Zafred, Domen, Shun-Shion, Amber S.M., Hodder, Anthony J., Bliss, Deepa, Metcalfe, Andrew, Edgar, James R., Gordon, David E., Sayers, Jon R., Nicklin, Martin J., Carroll, Miles, Collini, Paul J., Brown, Stephen, de Silva, Thushan I., Peden, Andrew A.

“…The prevalence and strength of serological responses mounted toward SARS-CoV-2 proteins other than nucleocapsid (N) and spike (S), which may be of use as…”
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Intracellular function of interleukin-1 receptor antagonist in ischemic cardiomyocytes by Vecile, Elena, Dobrina, Aldo, Salloum, Fadi N, Van Tassell, Benjamin W, Falcione, Antonella, Gustini, Edoardo, Secchiero, Samuele, Crovella, Sergio, Sinagra, Gianfranco, Finato, Nicoletta, Nicklin, Martin J, Abbate, Antonio

“…Loss of cardiac myocytes due to apoptosis is a relevant feature of ischemic heart disease. It has been described in infarct and peri-infarct regions of the…”
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Global Potato Yields Increase Under Climate Change With Adaptation and CO2 Fertilisation by Jennings, Stewart A., Koehler, Ann-Kristin, Nicklin, Kathryn J., Deva, Chetan, Sait, Steven M., Challinor, Andrew J.

“…The contribution of potatoes to the global food supply is increasing—consumption more than doubled in developing countries between 1960 and 2005. Understanding…”
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Cervical perivascular epithelioid cell tumour (PEComa) of the uterine cervix: cytological findings in a cervical smear by Stone, J. L., Batty, T., Nicklin, J.

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Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust by Colton, Hayley, Hodgson, David, Hornsby, Hailey, Brown, Rebecca, Mckenzie, Joanne, Bradley, Kirsty L., James, Cameron, Lindsey, Benjamin B., Birch, Sarah, Marsh, Louise, Wood, Steven, Bayley, Martin, Dickson, Gary, James, David C., Nicklin, Martin J., Sayers, Jon R., Zafred, Domen, Rowland-Jones, Sarah L., Kudesia, Goura, Kucharski, Adam, Darton, Thomas C., de Silva, Thushan I., Collini, Paul J.

“…Background: We aimed to measure SARS-CoV-2 seroprevalence in a cohort of healthcare workers (HCWs) during the first UK wave of the COVID-19 pandemic, explore…”
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Validity And Responsiveness Of The Bristol Rheumatoid Arthritis Fatigue Multidimensional Questionnaire (BRAF-MDQ) In A Randomized Controlled Clinical Trial by Kirwan, J, Coteur, G, Dures, E, Nicklin, J, Bryson, J, Hewlett, S

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Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents by Somm, E, Cettour-Rose, P, Asensio, C, Charollais, A, Klein, M, Theander-Carrillo, C, Juge-Aubry, C. E, Dayer, J. -M, Nicklin, M. J. H, Meda, P, Rohner-Jeanrenaud, F, Meier, C. A

“…Aims/hypothesis The IL-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine known to antagonise the actions of IL-1. We have previously shown that…”
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Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust by Colton, Hayley, Hodgson, David, Hornsby, Hailey, Brown, Rebecca, Mckenzie, Joanne, Bradley, Kirsty L, James, Cameron, Lindsey, Benjamin B, Birch, Sarah, Marsh, Louise, Wood, Steven, Bayley, Martin, Dickson, Gary, James, David C, Nicklin, Martin J, Sayers, Jon R, Zafred, Domen, Rowland-Jones, Sarah L, Kudesia, Goura, Kucharski, Adam, Darton, Thomas C, de Silva, Thushan I, Collini, Paul J

“…We aimed to measure SARS-CoV-2 seroprevalence in a cohort of healthcare workers (HCWs) during the first UK wave of the COVID-19 pandemic, explore risk factors…”
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Consideration for safe and effective gynaecological laparoscopy in the obese patient by Hackethal, A., Brennan, D., Rao, A., Land, R., Obermair, A., Nicklin, J., Garrett, A., Nascimento, M., Crandon, A., Perrin, L., Chetty, N.

“…Background The number of obese and morbidly obese patients within the developed world is dramatically increasing within the last 20 years. Apart from…”
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Decreased fat mass in interleukin-1 receptor antagonist-deficient mice : Impact on adipogenesis, food intake, and energy expenditure by SOMM, Emmanuel, HENRICHOT, Elvire, PERNIN, Agnès, JUGE-AUBRY, Cristiana E, MUZZIN, Patrick, DAYER, Jean-Michel, NICKLIN, Martin J. H, MEIER, Christoph A

“…Interleukin (IL)-1 is a regulator of inflammation but is also implicated in the control of energy homeostasis. Because the soluble IL-1 receptor antagonist…”
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Association between quality of life scores and short-term outcome after surgery for cancer of the oesophagus or gastric cardia by Blazeby, J. M., Metcalfe, C., Nicklin, J., Barham, C. P., Donovan, J., Alderson, D.

“…Background: Evidence suggests that baseline quality of life (QOL) scores are independently prognostic for survival in patients with cancer, but the role of QOL…”
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