Search Results - "Nicklay, Joshua J"
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Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition
Published in Cell reports (Cambridge) (17-03-2015)“…Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos. During embryogenesis, regulation of Npm histone binding is critical for…”
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Monitoring the Inflammatory Response to Infection through the Integration of MALDI IMS and MRI
Published in Cell host & microbe (14-06-2012)“…Systemic bacterial infection is characterized by a robust whole-organism inflammatory response. Analysis of the immune response to infection involves…”
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Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development
Published in Epigenetics & chromatin (06-09-2014)“…Stored, soluble histones in eggs are essential for early development, in particular during the maternally controlled early cell cycles in the absence of…”
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Localized in Situ Hydrogel-Mediated Protein Digestion and Extraction Technique for on-Tissue Analysis
Published in Analytical chemistry (Washington) (05-03-2013)“…A simultaneous on-tissue proteolytic digestion and extraction method is described for the in situ analysis of proteins from spatially distinct areas of a…”
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MALDI Imaging and in Situ Identification of Integral Membrane Proteins from Rat Brain Tissue Sections
Published in Analytical chemistry (Washington) (06-08-2013)“…Transmembrane proteins are greatly underrepresented in data generated by imaging mass spectrometry (IMS) because of analytical challenges related to their size…”
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Imaging mass spectrometry for assessing temporal proteomics: Analysis of calprotectin in Acinetobacter baumannii pulmonary infection
Published in Proteomics (Weinheim) (01-04-2014)“…Imaging MS is routinely used to show spatial localization of proteins within a tissue sample and can also be employed to study temporal protein dynamics. The…”
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7
Mass Spectrometry of Membrane Proteins: A Focus on Aquaporins
Published in Biochemistry (Easton) (04-06-2013)“…Membrane proteins are abundant, critically important biomolecules that conduct essential functions in all cells and are the targets of a significant number of…”
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Application of wide selected-ion monitoring data-independent acquisition to identify tomato fruit proteins regulated by the CUTIN DEFICIENT2 transcription factor
Published in Proteomics (Weinheim) (01-08-2016)“…We describe here the use of label‐free wide selected‐ion monitoring data‐independent acquisition (WiSIM‐DIA) to identify proteins that are involved in the…”
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Analysis of Histones in Xenopus laevis: I. A DISTINCT INDEX OF ENRICHED VARIANTS AND MODIFICATIONS EXISTS IN EACH CELL TYPE AND IS REMODELED DURING DEVELOPMENTAL TRANSITIONS
Published in The Journal of biological chemistry (09-01-2009)“…Histone proteins contain epigenetic information that is encoded both in the relative abundance of core histones and variants and particularly in the…”
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Analysis of Histones in Xenopus laevis: II. MASS SPECTROMETRY REVEALS AN INDEX OF CELL TYPE-SPECIFIC MODIFICATIONS ON H3 AND H4
Published in The Journal of biological chemistry (09-01-2009)“…Epigenetic information is hypothesized to be encoded in histone variants and post-translational modifications. Varied cell- and locus-specific combinations of…”
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Oxidation of 5-thio-2-nitrobenzoic acid, by the biologically relevant oxidants peroxynitrite anion, hydrogen peroxide and hypochlorous acid
Published in Nitric oxide (01-02-2008)“…The modification of protein and non-protein thiols by oxidants including hydrogen peroxide (H 2O 2), peroxynitrite anion (ONOO −) and hypochlorous acid (HOCl)…”
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12
Analysis of Histones in Xenopus laevis
Published in The Journal of biological chemistry (09-01-2009)“…Histone proteins contain epigenetic information that is encoded both in the relative abundance of core histones and variants and particularly in the…”
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13
Analysis of Histones in Xenopus laevis
Published in The Journal of biological chemistry (09-01-2009)“…Epigenetic information is hypothesized to be encoded in histone variants and post-translational modifications. Varied cell- and locus-specific combinations of…”
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14
Developmental regulation of histone H2A deposition via serine-1 phosphorylation
Published in Epigenetics & chromatin (18-03-2013)“…Doc number: P74…”
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