Search Results - "Nickerson, Philip E. B."

A transgenic mouse line expressing cre recombinase in undifferentiated postmitotic mouse retinal bipolar cell precursors by Nickerson, Philip E B, Ronellenfitch, Kara, McEwan, Jason, Kim, Howard, McInnes, Roderick R, Chow, Robert L

“…Approaches for manipulating cell type-specific gene expression during development depend on the identification of novel genetic tools. Here, we report the…”
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Material Exchange in Photoreceptor Transplantation: Updating Our Understanding of Donor/Host Communication and the Future of Cell Engraftment Science by Nickerson, Philip E B, Ortin-Martinez, Arturo, Wallace, Valerie A

“…Considerable research effort has been invested into the transplantation of mammalian photoreceptors into healthy and degenerating mouse eyes. Several platforms…”
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Sortilin regulates sorting and secretion of Sonic hedgehog by Campbell, Charles, Beug, Shawn, Nickerson, Philip E B, Peng, Jimmy, Mazerolle, Chantal, Bassett, Erin A, Ringuette, Randy, Jama, Fadumo A, Morales, Carlos, Christ, Annabel, Wallace, Valerie A

“…Sonic Hedgehog (Shh) is a secreted morphogen that is an essential regulator of patterning and growth. The Shh full-length protein undergoes autocleavage in the…”
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ARS2 is required for retinal progenitor cell S-phase progression and Müller glial cell fate specification by O'Sullivan, Connor, Nickerson, Philip E B, Krupke, Oliver, Christie, Jennifer, Chen, Li-Li, Mesa-Peres, Monica, Zhu, Minyan, Ryan, Bridget, Chow, Robert L, Howard, Perry L

“…During a developmental period that extends postnatally in the mouse, proliferating multipotent retinal progenitor cells produce one of 7 major cell types (rod,…”
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Mutagenesis of ARS2 Domains To Assess Possible Roles in Cell Cycle Progression and MicroRNA and Replication-Dependent Histone mRNA Biogenesis by O'Sullivan, Connor, Christie, Jennifer, Pienaar, Marcus, Gambling, Jake, Nickerson, Philip E. B., Alford, Spencer C., Chow, Robert L., Howard, Perry L.

“…ARS2 is a regulator of RNA polymerase II transcript processing through its role in the maturation of distinct nuclear cap-binding complex (CBC)-controlled RNA…”
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Requirement for the paired-like homeodomain transcription factor VSX1 in type 3a mouse retinal bipolar cell terminal differentiation by Shi, Zhiwei, Jervis, Drew, Nickerson, Philip E.B., Chow, Robert L.

“…Retinal bipolar cells make up a class of at least 11 distinct interneurons that have been classified through morphological and molecular approaches. Previous…”
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Proliferation and Expression of Progenitor and Mature Retinal Phenotypes in the Adult Mammalian Ciliary Body after Retinal Ganglion Cell Injury by Nickerson, Philip E. B, Emsley, Jason G, Myers, Tanya, Clarke, David B

“…Despite the identification of a small population of cells residing in the ciliary body (CB) of the adult mammalian eye that have the capacity to generate…”
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Nonswelling, Ultralow Content Inverse Electron‐Demand Diels–Alder Hyaluronan Hydrogels with Tunable Gelation Time: Synthesis and In Vitro Evaluation by Delplace, Vianney, Nickerson, Philip E. B., Ortin‐Martinez, Arturo, Baker, Alexander E. G., Wallace, Valerie A., Shoichet, Molly S.

“…Hyaluronan (HA) is a major component of the extracellular matrix and is particularly attractive for cell‐based assays; yet, common crosslinking strategies of…”
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Photoreceptor nanotubes mediate the in vivo exchange of intracellular material by Ortin‐Martinez, Arturo, Yan, Nicole E, Tsai, En Leh Samuel, Comanita, Lacrimioara, Gurdita, Akshay, Tachibana, Nobuhiko, Liu, Zhongda C, Lu, Suying, Dolati, Parnian, Pokrajac, Neno T, El‐Sehemy, Ahmed, Nickerson, Philip E B, Schuurmans, Carol, Bremner, Rod, Wallace, Valerie A

“…Emerging evidence suggests that intracellular molecules and organelles transfer between cells during embryonic development, tissue homeostasis and disease. We…”
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Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS by Tassew, Nardos G., Charish, Jason, Shabanzadeh, Alireza P., Luga, Valbona, Harada, Hidekiyo, Farhani, Nahal, D’Onofrio, Philippe, Choi, Brian, Ellabban, Ahmad, Nickerson, Philip E.B., Wallace, Valerie A., Koeberle, Paulo D., Wrana, Jeffrey L., Monnier, Philippe P.

“…Developing strategies that promote axonal regeneration within the injured CNS is a major therapeutic challenge, as axonal outgrowth is potently inhibited by…”
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Live imaging and analysis of postnatal mouse retinal development by Nickerson, Philip E B, Ronellenfitch, Kara M, Csuzdi, Nicklaus F, Boyd, Jamie D, Howard, Perry L, Delaney, Kerry R, Chow, Robert L

“…The explanted, developing rodent retina provides an efficient and accessible preparation for use in gene transfer and pharmacological experimentation. Many of…”
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Modeling of Photoreceptor Donor‐Host Interaction Following Transplantation Reveals a Role for Crx, Müller Glia, and Rho/ROCK Signaling in Neurite Outgrowth by Tsai, En L. S., Ortin‐Martinez, Arturo, Gurdita, Akshay, Comanita, Lacrimioara, Yan, Nicole, Smiley, Sheila, Delplace, Vianney, Shoichet, Molly S., Nickerson, Philip E. B., Wallace, Valerie A.

“…The goal of photoreceptor transplantation is to establish functional synaptic connectivity between donor cells and second‐order neurons in the host retina…”
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InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes by Gurdita, Akshay, Nickerson, Philip E.B., Pokrajac, Neno T., Ortín-Martínez, Arturo, Samuel Tsai, En Leh, Comanita, Lacrimioara, Yan, Nicole E., Dolati, Parnian, Tachibana, Nobuhiko, Liu, Zhongda C., Pearson, Joel D., Chen, Danian, Bremner, Rod, Wallace, Valerie A.

“…The mouse eye is used to model central nervous system development, pathology, angiogenesis, tumorigenesis, and regenerative therapies. To facilitate the…”
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Expression of Hsp27 in retinal ganglion cells of the rat during postnatal development by Hawkes, Erin L., Krueger-Naug, Anne Marie R., Nickerson, Philip E.B., Myers, Tanya L., Currie, R. William, Clarke, David B.

“…The small heat shock protein Hsp27 has been shown to protect neurons from apoptosis. We have recently shown the expression of Hsp27 in a subset of injured…”
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Sortilin regulates sorting and secretion of Sonic hedgehog by Campbell, Charles, Beug, Shawn, Nickerson, Philip E. B., Peng, Jimmy, Mazerolle, Chantal, Bassett, Erin A., Ringuette, Randy, Jama, Fadumo A., Morales, Carlos, Christ, Annabel, Wallace, Valerie A.

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