Search Results - "Nickerson, P"

Crohn's disease-associated adherent-invasive Escherichia coli adhesion is enhanced by exposure to the ubiquitous dietary polysaccharide maltodextrin by Nickerson, Kourtney P, McDonald, Christine

“…Crohn's disease (CD) is associated with intestinal dysbiosis evidenced by an altered microbiome forming thick biofilms on the epithelium. Additionally,…”
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Evolution and Clinical Pathologic Correlations of De Novo Donor‐Specific HLA Antibody Post Kidney Transplant by Wiebe, C., Gibson, I. W., Blydt‐Hansen, T. D., Karpinski, M., Ho, J., Storsley, L. J., Goldberg, A., Birk, P. E., Rush, D. N., Nickerson, P. W.

“…The natural history for patients with de novo donor‐specific antibodies (dnDSA) and the risk factors for its development have not been well defined…”
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Class II HLA Epitope Matching—A Strategy to Minimize De Novo Donor‐Specific Antibody Development and Improve Outcomes by Wiebe, C., Pochinco, D., Blydt‐Hansen, T. D., Ho, J., Birk, P. E., Karpinski, M., Goldberg, A., Storsley, L. J., Gibson, I. W., Rush, D. N., Nickerson, P. W.

“…De novo donor‐specific antibody (dnDSA) develops in 15–25% of renal transplant recipients within 5 years of transplantation and is associated with 40% lower…”
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A semantics, energy-based approach to automate biomodel composition by Shahidi, Niloofar, Pan, Michael, Tran, Kenneth, Crampin, Edmund J, Nickerson, David P

“…Hierarchical modelling is essential to achieving complex, large-scale models. However, not all modelling schemes support hierarchical composition, and…”
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The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell–mediated rejection, antibody‐mediated rejection, and prospects for integrative endpoints for next‐generation clinical trials by Haas, M., Loupy, A., Lefaucheur, C., Roufosse, C., Glotz, D., Seron, D., Nankivell, B. J., Halloran, P. F., Colvin, R. B., Akalin, Enver, Alachkar, N., Bagnasco, S., Bouatou, Y., Becker, J. U., Cornell, L. D., Huyen, J. P. Duong, Gibson, I. W., Kraus, Edward S., Mannon, R. B., Naesens, M., Nickeleit, V., Nickerson, P., Segev, D. L., Singh, H. K., Stegall, M., Randhawa, P., Racusen, L., Solez, K., Mengel, M.

“…The kidney sessions of the 2017 Banff Conference focused on 2 areas: clinical implications of inflammation in areas of interstitial fibrosis and tubular…”
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The Synergistic Effect of Class II HLA Epitope‐Mismatch and Nonadherence on Acute Rejection and Graft Survival by Wiebe, C., Nevins, T. E., Robiner, W. N., Thomas, W., Matas, A. J., Nickerson, P. W.

“…Predicting long‐term outcomes in renal transplant recipients is essential to optimize medical therapy and determine the frequency of posttransplant histologic…”
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The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn's Disease-Like Ileitis by Rodriguez-Palacios, Alexander, Harding, Andrew, Menghini, Paola, Himmelman, Catherine, Retuerto, Mauricio, Nickerson, Kourtney P, Lam, Minh, Croniger, Colleen M, McLean, Mairi H, Durum, Scott K, Pizarro, Theresa T, Ghannoum, Mahmoud A, Ilic, Sanja, McDonald, Christine, Cominelli, Fabio

“…Abstract Background Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn's disease (CD). Herein, we experimentally…”
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Rates and Determinants of Progression to Graft Failure in Kidney Allograft Recipients With De Novo Donor‐Specific Antibody by Wiebe, C., Gibson, I. W., Blydt‐Hansen, T. D., Pochinco, D., Birk, P. E., Ho, J., Karpinski, M., Goldberg, A., Storsley, L., Rush, D. N., Nickerson, P. W.

“…Understanding rates and determinants of clinical pathologic progression for recipients with de novo donor‐specific antibody (dnDSA), especially subclinical…”
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Multicenter Validation of Urinary CXCL9 as a Risk‐Stratifying Biomarker for Kidney Transplant Injury by Hricik, D. E., Nickerson, P., Formica, R. N., Poggio, E. D., Rush, D., Newell, K. A., Goebel, J., Gibson, I. W., Fairchild, R. L., Riggs, M., Spain, K., Ikle, D., Bridges, N. D., Heeger, P. S.

“…Noninvasive biomarkers are needed to assess immune risk and ultimately guide therapeutic decision‐making following kidney transplantation. A requisite step…”
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Comprehensive Assessment and Standardization of Solid Phase Multiplex‐Bead Arrays for the Detection of Antibodies to HLA by Reed, E. F., Rao, P., Zhang, Z., Gebel, H., Bray, R. A., Guleria, I., Lunz, J., Mohanakumar, T., Nickerson, P., Tambur, A. R., Zeevi, A., Heeger, P. S., Gjertson, D.

“…Solid phase multiplex‐bead arrays for the detection and characterization of HLA antibodies provide increased sensitivity and specificity compared to…”
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Survival of the Fittest: How Bacterial Pathogens Utilize Bile To Enhance Infection by Sistrunk, Jeticia R, Nickerson, Kourtney P, Chanin, Rachael B, Rasko, David A, Faherty, Christina S

“…Bacterial pathogens have coevolved with humans in order to efficiently infect, replicate within, and be transmitted to new hosts to ensure survival and a…”
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Making Time for Nature: Visual Exposure to Natural Environments Lengthens Subjective Time Perception and Reduces Impulsivity by Berry, Meredith S, Repke, Meredith A, Nickerson, Norma P, Conway, 3rd, Lucian G, Odum, Amy L, Jordan, Kerry E

“…Impulsivity in delay discounting is associated with maladaptive behaviors such as overeating and drug and alcohol abuse. Researchers have recently noted that…”
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A modular and reusable model of epithelial transport in the proximal convoluted tubule by Noroozbabaee, Leyla, Blanco, Pablo J, Safaei, Soroush, Nickerson, David P

“…We review a collection of published renal epithelial transport models, from which we build a consistent and reusable mathematical model able to reproduce many…”
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Randomized clinical trial of accelerated enhanced recovery after minimally invasive colorectal cancer surgery (RecoverMI trial) by Bednarski, B. K., Nickerson, T. P., You, Y. N., Messick, C. A., Speer, B., Gottumukkala, V., Manandhar, M., Weldon, M., Dean, E. M., Qiao, W., Wang, X., Chang, G. J.

“…Background Minimally invasive surgery (MIS) and enhanced recovery protocols (ERPs) have improved postoperative recovery and shortened length of hospital stay…”
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Hierarchical semantic composition of biosimulation models using bond graphs by Shahidi, Niloofar, Pan, Michael, Safaei, Soroush, Tran, Kenneth, Crampin, Edmund J, Nickerson, David P

“…Simulating complex biological and physiological systems and predicting their behaviours under different conditions remains challenging. Breaking systems into…”
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Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes by Nickerson, Daniel P, West, Matthew, Odorizzi, Greg

“…The sorting of transmembrane cargo proteins into the lumenal vesicles of multivesicular bodies (MVBs) depends on the recruitment of endosomal sorting complexes…”
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RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis by Leonard, Maureen M, Bai, Yu, Serena, Gloria, Nickerson, Kourtney P, Camhi, Stephanie, Sturgeon, Craig, Yan, Shu, Fiorentino, Maria R, Katz, Aubrey, Nath, Barbara, Richter, James, Sleeman, Matthew, Gurer, Cagan, Fasano, Alessio

“…The early steps in the pathophysiology of celiac disease (CD) leading to loss of tolerance to gluten are poorly described. Our aim was to use RNA sequencing of…”
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Model annotation and discovery with the Physiome Model Repository by Sarwar, Dewan M, Kalbasi, Reza, Gennari, John H, Carlson, Brian E, Neal, Maxwell L, Bono, Bernard de, Atalag, Koray, Hunter, Peter J, Nickerson, David P

“…Mathematics and Phy sics-based simulation models have the potential to help interpret and encapsulate biological phenomena in a computable and reproducible…”
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Evaluation of C1q Status and Titer of De Novo Donor‐Specific Antibodies as Predictors of Allograft Survival by Wiebe, C., Gareau, A. J., Pochinco, D., Gibson, I. W., Ho, J., Birk, P. E., Blydt‐Hansen, T., Karpinski, M., Goldberg, A., Storsley, L., Rush, D. N., Nickerson, P. W.

“…De novo donor‐specific antibodies (dnDSAs) that develop after renal transplantation are independent predictors of allograft loss. However, it is unknown if…”
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Ubiquitin binding by the CUE domain promotes endosomal localization of the Rab5 GEF Vps9 by Shideler, Tess, Nickerson, Daniel P, Merz, Alexey J, Odorizzi, Greg

“…Vps9 and Muk1 are guanine nucleotide exchange factors (GEFs) in Saccharomyces cerevisiae that regulate membrane trafficking in the endolysosomal pathway by…”
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