Search Results - "Nickerson, David F."

Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene by Rosati, Robert L, Da Silva Jardine, Paul, Cameron, Kimberly O, Thompson, David D, Ke, Hua Zhu, Toler, Steven M, Brown, Thomas A, Pan, Lydia C, Ebbinghaus, Charles F, Reinhold, Anthony R, Elliott, Nancy C, Newhouse, Bradley N, Tjoa, Christina M, Sweetnam, Paul M, Cole, Mark J, Arriola, Mark W, Gauthier, Jeffrey W, Crawford, D. Todd, Nickerson, David F, Pirie, Christine M, Qi, Hong, Simmons, Hollis A, Tkalcevic, George T

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Monitoring the quality of conduct of clinical trials: a survey of current practices by Morrison, Briggs W, Cochran, Chrissy J, White, Jennifer Giangrande, Harley, Joan, Kleppinger, Cynthia F, Liu, An, Mitchel, Jules T, Nickerson, David F, Zacharias, Cynthia R, Kramer, Judith M, Neaton, James D

“…Background There is a little empirical evidence to determine which, if any, monitoring practices best achieve the goals of trial monitoring set forth in ICH E6…”
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Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs): Discovery of capromorelin by Carpino, Philip A, Lefker, Bruce A, Toler, Steven M, Pan, Lydia C, Hadcock, John R, Cook, Ewell R, DiBrino, Joseph N, Campeta, Anthony M, DeNinno, Shari L, Chidsey-Frink, Kristin L, Hada, William A, Inthavongsay, John, Mangano, F.Michael, Mullins, Michelle A, Nickerson, David F, Ng, Oicheng, Pirie, Christine M, Ragan, John A, Rose, Colin R, Tess, David A, Wright, Ann S, Yu, Li, Zawistoski, Michael P, DaSilva-Jardine, Paul A, Wilson, Theresa C, Thompson, David D

“…Novel pyrazolinone-piperidine dipeptide derivatives were synthesized and evaluated as growth hormone secretagogues (GHSs). Two analogues, capromorelin ( 5,…”
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Discovery and biological characterization of capromorelin analogues with extended half-lives by Carpino, Philip A., Lefker, Bruce A., Toler, Steven M., Pan, Lydia C., Hadcock, John R., Murray, Marianne C., Cook, Ewell R., DiBrino, Joseph N., DeNinno, Shari L., Chidsey-Frink, Kristin L., Hada, William A., Inthavongsay, John, Lewis, Sharon K., Mangano, F.Michael, Mullins, Michelle A., Nickerson, David F., Ng, Oicheng, Pirie, Christine M., Ragan, John A., Rose, Colin R., Tess, David A., Wright, Ann S., Yu, Li, Zawistoski, Michael P., Pettersen, John C., DaSilva-Jardine, Paul A., Wilson, Theresa C., Thompson, David D.

“…New tert-butyl, picolyl and fluorinated analogues of capromorelin ( 3), a short-acting growth hormone secretagogue (GHS), were prepared as part of a program to…”
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Theoretical study of cis-trans isomerization in simple transition-metal complexes by Marynick, Dennis S, Askari, Sasan, Nickerson, David F

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Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs) by Carpino, Philip A, Lefker, Bruce A, Toler, Steven M, Pan, Lydia C, Hadcock, John R, Cook, Ewell R, DiBrino, Joseph N, Campeta, Anthony M, DeNinno, Shari L, Chidsey-Frink, Kristin L, Hada, William A, Inthavongsay, John, Mangano, F.Michael, Mullins, Michelle A, Nickerson, David F, Ng, Oicheng, Pirie, Christine M, Ragan, John A, Rose, Colin R, Tess, David A, Wright, Ann S, Yu, Li, Zawistoski, Michael P, DaSilva-Jardine, Paul A, Wilson, Theresa C, Thompson, David D

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Binding of fluvastatin to blood cells and plasma proteins by Tse, F L, Nickerson, D F, Yardley, W S

“…The binding of fluvastatin, an inhibitor of hydroxymethylglutaryl coenzyme A reductase, to plasma proteins and red blood cells of rat, dog, and human in vitro…”
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First-pass metabolism and biliary recirculation of droloxifene in the female Sprague- Dawley rat by NICKERSON, DAVID F., TESS, DAVID A., TOLER, STEVEN M.

“…1. Utilizing a validated ultrasensitive hplc assay (lower limit of quantitation 25 pg/ml), we characterized the disposition profile of droloxifene in the…”
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The effect of oral dose volume on the absorption of a highly and a poorly water-soluble drug in the rat by Nickerson, D F, Weaver, M L, Tse, F L

“…The influence of dose volume on drug absorption following oral administration of a highly and a poorly water soluble drug was examined in male Sprague-Dawley…”
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