Search Results - "Nickel, Nils"

BMPR2 Preserves Mitochondrial Function and DNA during Reoxygenation to Promote Endothelial Cell Survival and Reverse Pulmonary Hypertension by Diebold, Isabel, Hennigs, Jan K., Miyagawa, Kazuya, Li, Caiyun G., Nickel, Nils P., Kaschwich, Mark, Cao, Aiqin, Wang, Lingli, Reddy, Sushma, Chen, Pin-I, Nakahira, Kiichi, Alcazar, Miguel A. Alejandre, Hopper, Rachel K., Ji, Lijuan, Feldman, Brian J., Rabinovitch, Marlene

“…Mitochondrial dysfunction, inflammation, and mutant bone morphogenetic protein receptor 2 (BMPR2) are associated with pulmonary arterial hypertension (PAH), an…”
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Beyond the Lungs: Systemic Manifestations of Pulmonary Arterial Hypertension by Nickel, Nils P, Yuan, Ke, Dorfmuller, Peter, Provencher, Steeve, Lai, Yen-Chun, Bonnet, Sebastien, Austin, Eric D, Koch, Carl D, Morris, Alison, Perros, Frédéric, Montani, David, Zamanian, Roham T, de Jesus Perez, Vinicio A

“…Pulmonary arterial hypertension (PAH) is a disease characterized by progressive loss and remodeling of the pulmonary arteries, resulting in right heart failure…”
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Letter to the Editor: Reduced-Dose Thrombolysis for Acute Pulmonary Embolism by Murguia, Adrian Rojas, Mukherjee, Debabrata, Ojha, Chandra, Rajachandran, Manu, Nickel, Nils P.

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Atrial flutter and fibrillation in patients with pulmonary hypertension by Olsson, Karen M, Nickel, Nils P, Tongers, Jörn, Hoeper, Marius M

“…Abstract Background Atrial flutter and fibrillation are being increasingly reported in patients with pulmonary hypertension but little is known about their…”
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Targeted Therapies in Patients with Pulmonary Arterial Hypertension Due to Congenital Heart Disease by Mares, Adriana, Mukherjee, Debabrata, Lange, Richard A, Nickel, Nils P

“…Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disease leading to right heart failure and death if untreated. Medical therapies for PAH…”
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Contemporary Treatment of Pulmonary Embolism: Medical Treatment and Management by Moreland, Stephen, Mukherjee, Debabrata, Nickel, Nils P

“…Pulmonary embolus (PE) is defined as obstruction of the pulmonary artery or one of its branches by material (e.g., thrombus, tumor, air, or fat) but most…”
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The 6th World Symposium on Pulmonary Hypertension: what's old is new [version 1; peer review: 3 approved] by Condon, David F, Nickel, Nils P, Anderson, Ryan, Mirza, Shireen, de Jesus Perez, Vinicio A

“…In February 2018, the 6th World Symposium on Pulmonary Hypertension (WSPH) brought together experts from various disciplines to review the most relevant…”
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Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling by Nickel, Nils P, Spiekerkoetter, Edda, Gu, Mingxia, Li, Caiyun G, Li, Hai, Kaschwich, Mark, Diebold, Isabel, Hennigs, Jan K, Kim, Ki-Yoon, Miyagawa, Kazuya, Wang, Lingli, Cao, Aiqin, Sa, Silin, Jiang, Xinguo, Stockstill, Raymond W, Nicolls, Mark R, Zamanian, Roham T, Bland, Richard D, Rabinovitch, Marlene

“…Pulmonary arterial hypertension is characterized by endothelial dysfunction, impaired bone morphogenetic protein receptor 2 (BMPR2) signaling, and increased…”
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Prevalence and clinical significance of deep vein thrombosis in Hispanic patients with acute pulmonary embolism by Murguia, Adrian Rojas, Prakash, Swathi, Segovia, Fernando, Ayvali, Fatih, Brockman, Michael, Nadella, Sahithi, Singh, Vishwajeet, Dwivedi, Alok Kumar, Rajachandran, Manu, Mukherjee, Debabrata, Nickel, Nils P

“…The prevalence of concomitant deep vein thrombosis (DVT) and its impact on 30-day outcomes in Hispanic patients with acute pulmonary embolism (PE) is unknown…”
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PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis by Li, Caiyun G., Mahon, Cathal, Sweeney, Nathaly M., Verschueren, Erik, Kantamani, Vivek, Li, Dan, Hennigs, Jan K., Marciano, David P., Diebold, Isabel, Abu-Halawa, Ossama, Elliott, Matthew, Sa, Silin, Guo, Feng, Wang, Lingli, Cao, Aiqin, Guignabert, Christophe, Sollier, Julie, Nickel, Nils P., Kaschwich, Mark, Cimprich, Karlene A., Rabinovitch, Marlene

“…Using proteomic approaches, we uncovered a DNA damage response (DDR) function for peroxisome proliferator activated receptor γ (PPARγ) through its interaction…”
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Reduced-Dose Thrombolysis in Acute Pulmonary Embolism A Systematic Review by Murguia, Adrian Rojas, Mukherjee, Debabrata, Ojha, Chandra, Rajachandran, Manu, Siddiqui, Tariq S., Nickel, Nils P.

“…Pulmonary embolism (PE) is the third-leading cause of cardiovascular mortality and the second-leading cause of death in cancer patients. The clinical efficacy…”
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Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension by Sawada, Hirofumi, Saito, Toshie, Nickel, Nils P, Alastalo, Tero-Pekka, Glotzbach, Jason P, Chan, Roshelle, Haghighat, Leila, Fuchs, Gabriele, Januszyk, Michael, Cao, Aiqin, Lai, Ying-Ju, Perez, Vinicio de Jesus, Kim, Yu-Mee, Wang, Lingli, Chen, Pin-I, Spiekerkoetter, Edda, Mitani, Yoshihide, Gurtner, Geoffrey C, Sarnow, Peter, Rabinovitch, Marlene

“…Idiopathic pulmonary arterial hypertension (PAH [IPAH]) is an insidious and potentially fatal disease linked to a mutation or reduced expression of bone…”
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Evaluation of Four Validated Risk Scores to Predict Outcomes in Hispanic Patients With Acute Pulmonary Embolism by Murguia, Adrian Rojas, Segovia, Fernando, Ayvali, Fatih, Brockman, Michael, Prakash, Swathi, Singh, Vishwajeet, Dwivedi, Alok Kumar, Rajachandran, Manu, Mukherjee, Debabrata, Nickel, Nils P

“…Risk stratification plays an essential role in the management of acute pulmonary embolism (PE). Several risk scores have been studied to support risk…”
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Insights Into Differences in Pulmonary Hemodynamics in Hispanic Patients With Pulmonary Arterial Hypertension by Fadah, Kahtan, Arrington, Kedzie, Khalafi, Seyed, Brockman, Michael, Garcia, Hernando, Alkhateeb, Haider, Mukherjee, Debabrata, Nickel, Nils P

“…Emerging data suggest that Hispanic patients with pulmonary arterial hypertension (PAH) exhibit improved survival rates compared to individuals of other…”
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Circulating levels of copeptin predict outcome in patients with pulmonary arterial hypertension by Nickel, Nils P, Lichtinghagen, Ralf, Golpon, Heiko, Olsson, Karen M, Brand, Korbinian, Welte, Tobias, Hoeper, Marius M

“…To determine the levels of circulating copeptin in patients with pulmonary arterial hypertension (PAH), and to evaluate its relation with disease severity,…”
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RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension by Rhodes, Christopher J, Im, Hogune, Cao, Aiqin, Hennigs, Jan K, Wang, Lingli, Sa, Silin, Chen, Pin-I, Nickel, Nils P, Miyagawa, Kazuya, Hopper, Rachel K, Tojais, Nancy F, Li, Caiyun G, Gu, Mingxia, Spiekerkoetter, Edda, Xian, Zhaoying, Chen, Rui, Zhao, Mingming, Kaschwich, Mark, Del Rosario, Patricia A, Bernstein, Daniel, Zamanian, Roham T, Wu, Joseph C, Snyder, Michael P, Rabinovitch, Marlene

“…Pulmonary arterial hypertension is characterized by endothelial dysregulation, but global changes in gene expression have not been related to perturbations in…”
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Low-Dose Alteplase versus Conventional Anticoagulation to treat Submassive Pulmonary Embolism in Hispanic Patients by Zientek, Emily, Talkington, Kelsey, Gardner, Joshua, Guo, Yi, Mukherjee, Debabrata, Rajachandran, Manu, Siddiqui, Tariq S, Nickel, Nils P

“…The use of low-dose tissue plasminogen activator (tPA) in Hispanic patients with submassive pulmonary embolism (PE) is understudied. The purpose of this study…”
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Circulating angiopoietins in idiopathic pulmonary arterial hypertension by Kümpers, Philipp, Nickel, Nils, Lukasz, Alexander, Golpon, Heiko, Westerkamp, Volker, Olsson, Karen M., Jonigk, Danny, Maegel, Lavinia, Bockmeyer, Clemens L., David, Sascha, Hoeper, Marius M.

“…Aims To determine the diagnostic utility of circulating angiopoietin-1 (Ang-1) and its antagonist angiopoietin-2 (Ang-2) as potential biomarkers of disease…”
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Prognosis in Hispanic patient population with pulmonary arterial hypertension: An application of common risk stratification models by Fadah, Kahtan, Cruz Rodriguez, Jose B, Alkhateeb, Haider, Mukherjee, Debabrata, Garcia, Hernando, Schuller, Dan, Mohammad, Khan O, Sahay, Sandeep, Nickel, Nils P

“…Pulmonary arterial hypertension (PAH) is a cardiovascular disease with high mortality rate. Current guidelines propose initiation and escalation of…”
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Liver abnormalities in pulmonary arterial hypertension by Nickel, Nils P., Galura, Gian M., Zuckerman, Marc J., Hakim, M. Nawar, Alkhateeb, Haider, Mukherjee, Debabrata, Austin, Eric D., Heresi, Gustavo A.

“…Pulmonary arterial hypertension (PAH) is a cardiopulmonary disease with high mortality. In recent years, it has been recognized that PAH is a multi-organ…”
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