Search Results - "Nicholson, Lindsay D."

Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor by Duan, Shengquan, Widlicka, Daniel W, Burns, Michael P, Kumar, Rajesh, Hotham, Ian, Desrosiers, Jean-Nicolas, Bowles, Paul, Jones, Kris N, Nicholson, Lindsay D, Buetti-Weekly, Michele T, Han, Lu, Steflik, Jeremy, Hansen, Eric, Hayward, Cheryl M, Strohmeyer, Holly, Monfette, Sébastien, Sutton, Scott C, Morris, Christopher

“…Biocatalytic reductive amination catalyzed by engineered imine reductase (RedAms) is a new and powerful tool for the synthesis of substituted chiral amines…”
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Synthesis of Nirmatrelvir: Design and Optimization of an Efficient Telescoped Amidation–Dehydration Sequence by Algera, Russell F., Baldwin, Aaron F., Bowles, Paul, Clarke, Hugh J., Connor, Christina G., Cordi, Eric M., Do, Nga M., Nicholson, Lindsay D., Georgian, William, Happe, Alan, Herman, Madeline I., Hilou, Elaa, James, Chintelle, Johnson, Amber M., Kalinowski, Maciej, Kulkarni, Samir A., Launer-Felty, Katherine D., Lee, Johnny W., Lee, Taegyo, Lopez, Jorge, McInturff, Emma L., Piper, Jared L., Place, David W., Ragan, John A., Rauschenberger, Blake, Ryder, Katherine, Stanley, Michael, Weisenburger, Gerald A., Weekly, R. Matthew, Allais, Christophe

“…Development of a scalable route for the synthesis of nirmatrelvir, the novel SARS-CoV-2 3C-like protease inhibitor discovered in 2020 by Pfizer scientists, was…”
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