Search Results - "Nicholson, Linda J"
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Cancer stem cells: problems for therapy
Published in The Journal of pathology (01-01-2011)“…Many, if not all, tumours contain a sub-population of self-renewing and expanding stem cells known as cancer stem cells (CSCs). The symmetric division of CSCs…”
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Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose
Published in The Journal of pathology (01-12-2010)“…Despite many years of intensive effort, there is surprisingly little consensus on the most suitable markers with which to locate and isolate stem cells from…”
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Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum‐induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer
Published in International journal of cancer (15-09-2009)“…Evidence indicates that acquired resistance of cancers to chemotherapeutic agents can occur via epigenetic mechanisms. Down‐regulation of expression of…”
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Epigenetic Inactivation Implies Independent Functions for Insulin-like Growth Factor Binding Protein (IGFBP)-Related Protein 1 and the Related IGFBPL1 in Inhibiting Breast Cancer Phenotypes
Published in Clinical cancer research (15-07-2007)“…Purpose: To analyze epigenetic regulation of two related genes, insulin-like growth factor binding protein-related protein 1 ( IGFBP-rP1 ) and IGFBPL1 , and…”
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RNA interference mediated in human primary cells via recombinant baculoviral vectors
Published in Molecular therapy (01-04-2005)“…The success of RNA interference (RNAi) in mammalian cells, mediated by siRNAs or shRNA-generating plasmids, is dependent, to an extent, upon transfection…”
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Cancer stem cells: In the line of fire
Published in Cancer treatment reviews (01-10-2012)“…Abstract Most tumours appear to contain a sub-population (s) of self-renewing and expanding stem cells known as cancer stem cells (CSCs). The CSC model…”
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Chronic inflammation and hepatocellular carcinoma
Published in Recent results in cancer research (01-01-2011)“…Hepatocellular carcinoma (HCC) invariably develops within a setting of chronic inflammation caused by either hepatotropic viruses, toxins, metabolic liver…”
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Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter
Published in The Journal of clinical investigation (01-08-2010)“…The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer…”
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Counter-selection recombineering of the baculovirus genome: a strategy for seamless modification of repeat-containing BACs
Published in Nucleic acids research (01-09-2010)“…Recombineering is employed to modify large DNA clones such as fosmids, BACs and PACs. Subtle and seamless modifications can be achieved using counter-selection…”
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Seamless replacement of Autographa californica multiple nucleopolyhedrovirus gp64 with each of five novel type II alphabaculovirus fusion sequences generates pseudotyped virus that fails to transduce mammalian cells
Published in Journal of general virology (01-07-2012)“…Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a member of the type I alphabaculoviruses, is able to transduce and deliver a functional gene to…”
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Ras‐MEK‐ERK signaling cascade regulates androgen receptor element‐inducible gene transcription and DNA synthesis in prostate cancer cells
Published in International journal of cancer (01-08-2007)“…Treatment of prostate cancer (CaP) patients frequently involves androgen ablation, but resistance often develops and androgen‐insensitive tumors emerge. The…”
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A new role for the anti-apoptotic gene A20 in angiogenesis
Published in Experimental cell research (10-09-2006)“…A20 is a negative regulator of NF-κB activation and thus a potential therapeutic tool for the treatment of diseases where apoptosis and/or inflammatory…”
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Regulation of keratinocyte terminal differentiation by integrin-extracellular matrix interactions
Published in Journal of cell science (01-09-1993)“…Suspension-induced terminal differentiation of human epidermal keratinocytes can be inhibited by fibronectin through binding to the alpha 5 beta 1 integrin. We…”
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A Response to My 'Critics'
Published in Hypatia (01-04-2001)“…Nicholson responds to the critics of her book "The Play Of Reason: From the Modern to the Postmodern"…”
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Revisioning Gender
Published in Hypatia (01-01-2001)“…"Revisioning Gender" edited by Myra Marx Feree, Judith Lorber and Beth B. Hess is reviewed…”
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Cancer stem cells: problems for therapy?: Cancer Biology and Genomics
Published in The Journal of pathology (2011)Get full text
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Declogging Small-Bore Feeding Tubes
Published in JPEN. Journal of parenteral and enteral nutrition (01-11-1987)“…Nine substances (Pancrease, Viokase, pork pancreatin, bromelain, papain, cranberry juice, Coca-Cola, chymotrypsin, and distilled water) were tested every…”
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Comment on Rosaldo's "The Use and Abuse of Anthropology"
Published in Signs: Journal of Women in Culture and Society (01-04-1982)Get full text
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Women, Morality, and History
Published in Social research (01-10-1983)Get full text
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