Search Results - "Nichols, William K."

3-Methylindole is Mutagenic and a Possible Pulmonary Carcinogen by Weems, Jessica M., Cutler, Ned. S., Moore, Chad, Nichols, William K., Martin, David, Makin, Evan, Lamb, John G., Yost, Garold S.

“…Previous work has shown that bioactivation of the cigarette smoke pneumotoxicant 3-methylindole (3MI) by pulmonary cytochrome P450 enzymes is directly…”
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Correlation of in Vitro Cytokine Responses with the Chemical Composition of Soil-Derived Particulate Matter by Veranth, John M., Moss, Tyler A., Chow, Judith C., Labban, Raed, Nichols, William K., Walton, John C., Watson, John G., Yost, Garold S.

“…We treated human lung epithelial cells, type BEAS-2B, with 10-80 μ g/ cm2 of dust from soils and road surfaces in the western United States that contained…”
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3-Methylindole-Induced Toxicity to Human Bronchial Epithelial Cell Lines by Nichols, William K., Mehta, Rashmi, Skordos, Konstantine, Macé, Katherine, Pfeifer, Andrea M. A., Carr, Brian A., Minko, Tamara, Burchiel, Scott W., Yost, Garold S.

“…Transfected BEAS-2B cells that express different cytochrome P450 enzymes were used to assess whether human bronchial epithelial cell lines are target cells for…”
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Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels by Kogan, F J, Nichols, W K, Gibb, J W

“…In previous reports, methamphetamine was shown to depress tyrosine hydroxylase (TH) activity in the rat corpus striatum. To evaluate further the mechanism of…”
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Cyclic Nucleotide Changes in Human Neutrophils Induced by Chemoattractants and Chemotactic Modulators by Hatch, Gary E, Nichols, William K, Hill, Harry R

“…Two classes of agents have effects on the chemotactic response of human neutrophils. Chemoattractants such as activated complement components, E. coli culture…”
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Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs by Thornton-Manning, J R, Nichols, W K, Manning, B W, Skiles, G L, Yost, G S

“…3-Methylindole (3MI), a fermentation product of tryptophan produced by intestinal and ruminal microflora, has been shown to cause pneumotoxicity in several…”
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Induction of ornithine decarboxylase in macrophages by bacterial lipopolysaccharides (LPS) and mycobacterial cell wall material by Nichols, W K, Prosser, F H

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Effect of heparin on platelet aggregation inhibited by PGI2, trifluoperazine and verapamil by Weber, D R, Nichols, W K, Mohammad, S F

“…The enhancement of platelet aggregation by heparin in the presence of certain inhibitors of aggregation was investigated in an attempt to discern the mechanism…”
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Inhibition of lymphocyte blastogenesis by factor(s) in alloxan-diabetic rat plasma by Pallavicini, M G, Nichols, W K

“…Supplementation of rat lymphocyte cultures with plasma from alloxan-diabetic rats produced a dose-dependent suppression of mitogen-induced blastogenic…”
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Induction of ornithine decarboxylase, RNA, and protein synthesis in macrophage cell lines stimulated by immunoadjuvants by Prosser, F H, Schmidt, C J, Nichols, S V, Nichols, W K

“…Early biochemical changes associated with adjuvant stimulation of macrophage protein synthesis were studied using two murine macrophage cell lines, PU5-1.8 and…”
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LPS stimulation of complement (C3) synthesis by a human monocyte cell line by Nichols, W K

“…The human monocyte-like cell line, U937, was utilized as a model system to assess the influence of lipopolysaccharides (LPS) from Escherichia coli and other…”
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A simplified procedure for cyclic nucleotide radioimmunoassay and its application to human blood leukocytes by Hatch, G E, Nichols, W K, Hill, H R

“…Rapid treatment of leukocyte suspensions was found to be an effective alternative to acid treatment in the preparation of these cells for radioimmunoassay of…”
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The relationship between insulin and apparent glucocorticoid-promoted activation of hepatic glycogen synthetase by Nichols, W K, Goldberg, N D

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Aldehyde oxidase activity during the perinatal period by Nichols, W K, Dixon, R L

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Bioactivation of halogenated hydrocarbons by rabbit pulmonary cells by Nichols, W K, Covington, M O, Seiders, C D, Safiullah, S, Yost, G S

“…1,1-Dichloro-2,2-bis (4'-chlorophenyl)ethane (DDD), 1,2-dibromoethane (DBE) and trichloroethylene are three halogenated hydrocarbons that selectively bind to…”
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Differential effects of cartilage-derived growth factor stimulation of collagen secretion by bovine aortic and microvascular endothelial cells by Nichols, W K, Marken, J M, Buckley, A, Klagsbrun, M, Davidson, J M

“…Cartilage-derived growth factor (CDGF), a protein closely related to basic fibroblast growth factor, is known to have both mitogenic and chemokinetic…”
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