Search Results - "Nichols, William"

Genetics and genomics of pulmonary arterial hypertension by Morrell, Nicholas W, Aldred, Micheala A, Chung, Wendy K, Elliott, C Gregory, Nichols, William C, Soubrier, Florent, Trembath, Richard C, Loyd, James E

“…Since 2000 there have been major advances in our understanding of the genetic and genomics of pulmonary arterial hypertension (PAH), although there remains…”
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The End to the Myth of Individual Programmer Productivity by Nichols, William R.

“…One often-quoted truism in software engineering is that good programmers are "much much better" than bad programmers. The size of "much much better" is widely…”
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Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers by Pal, Gian, Mangone, Graziella, Hill, Emily J., Ouyang, Bichun, Liu, Yuanqing, Lythe, Vanessa, Ehrlich, Debra, Saunders‐Pullman, Rachel, Shanker, Vicki, Bressman, Susan, Alcalay, Roy N., Garcia, Priscilla, Marder, Karen S., Aasly, Jan, Mouradian, M. Maral, Link, Samantha, Rosenbaum, Marc, Anderson, Sharlet, Bernard, Bryan, Wilson, Robert, Stebbins, Glenn, Nichols, William C., Welter, Marie‐Laure, Sani, Sepehr, Afshari, Mitra, Verhagen, Leo, Bie, Rob M.A., Foltynie, Tom, Hall, Deborah, Corvol, Jean‐Christophe, Goetz, Christopher G.

“…Objective This study was undertaken to compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and noncarriers with and…”
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Gabapentin: Abuse, Dependence, and Withdrawal by Mersfelder, Tracey L., Nichols, William H.

“…Objective: To identify case reports and studies regarding patients who abused, became dependent on, or experienced withdrawal from gabapentin. Data Sources: A…”
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Facile synthesis of Li2S-P2S5 glass-ceramics electrolyte with micron range particles for all-solid-state batteries via a low-temperature solution technique (LTST) by Choi, Sunho, Lee, Sewook, Park, Jongyeop, Nichols, William T., Shin, Dongwook

“…•A 75Li2S⋅25P2S5 glass-ceramics electrolyte is successfully synthesized via a LTST.•Highly lithium ion conductive thio-LISICON III analog phase is successfully…”
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An aphid symbiont confers protection against a specialized RNA virus, another increases vulnerability to the same pathogen by Higashi, Clesson H. V., Nichols, William L., Chevignon, Germain, Patel, Vilas, Allison, Suzanne E., Kim, Kyungsun Lee, Strand, Michael R., Oliver, Kerry M.

“…Insects often harbour heritable symbionts that provide defence against specialized natural enemies, yet little is known about symbiont protection when hosts…”
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Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations by Alcalay, Roy N, Levy, Oren A, Waters, Cheryl C, Fahn, Stanley, Ford, Blair, Kuo, Sheng-Han, Mazzoni, Pietro, Pauciulo, Michael W, Nichols, William C, Gan-Or, Ziv, Rouleau, Guy A, Chung, Wendy K, Wolf, Pavlina, Oliva, Petra, Keutzer, Joan, Marder, Karen, Zhang, Xiaokui

“…Glucocerebrosidase (GBA) mutations have been associated with Parkinson's disease in numerous studies. However, it is unknown whether the increased risk of…”
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Carbon-coated Li2S cathode for improving the electrochemical properties of an all-solid-state lithium-sulfur battery using Li2S-P2S5 solid electrolyte by Choi, Sunho, Yoon, Insang, Nichols, William T., Shin, Dongwook

“…Li2S is coated with carbon to improve the electrical conductivity of the composite cathode in all-solid-state lithium-sulfur batteries. Carbon is applied by…”
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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension by Potus, François, Pauciulo, Michael W., Cook, Elina K., Zhu, Na, Hsieh, Alexander, Welch, Carrie L., Shen, Yufeng, Tian, Lian, Lima, Patricia, Mewburn, Jeffrey, D’Arsigny, Christine L., Lutz, Katie A., Coleman, Anna W., Damico, Rachel, Snetsinger, Brooke, Martin, Ashley Y., Hassoun, Paul M., Nichols, William C., Chung, Wendy K., Rauh, Michael J., Archer, Stephen L.

“…BACKGROUND:Pulmonary arterial hypertension (PAH) is a lethal vasculopathy. Hereditary cases are associated with germline mutations in BMPR2 and 16 other genes…”
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Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension by Ulrich, Anna, Wharton, John, Thayer, Timothy E, Swietlik, Emilia M, Assad, Tufik R, Desai, Ankit A, Gräf, Stefan, Harbaum, Lars, Humbert, Marc, Morrell, Nicholas W, Nichols, William C, Soubrier, Florent, Southgate, Laura, Trégouët, David-Alexandre, Trembath, Richard C, Brittain, Evan L, Wilkins, Martin R, Prokopenko, Inga, Rhodes, Christopher J

“…Pulmonary arterial hypertension (PAH) is a rare disease that leads to premature death from right heart failure. It is strongly associated with elevated red…”
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Importance of mixing protocol for enhanced performance of composite cathodes in all-solid-state batteries using sulfide solid electrolyte by Noh, Sungwoo, Nichols, William T., Cho, Moonju, Shin, Dongwook

“…All-solid-state battery performance is strongly dependent on effective charge transfer at both 1) the interface of the active particles and 2) through the…”
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Enhanced energy density and electrochemical performance of all-solid-state lithium batteries through microstructural distribution of solid electrolyte by Noh, Sungwoo, Nichols, William T., Park, Chanhwi, Shin, Dongwook

“…Maximizing the proportion of active material in the composite cathode is a technical challenge for the All-Solid-State Lithium ion battery. Among viable…”
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High performance all-solid-state lithium-sulfur battery using a Li2S-VGCF nanocomposite by Eom, Minyong, Son, Seunghyeon, Park, Chanhwi, Noh, Sungwoo, Nichols, William T., Shin, Dongwook

“…In lithium-sulfur batteries, cyclability is often strongly limited by a high interfacial resistance caused by poor contact between the active material and…”
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Phenotype characterisation of TBX4 mutation and deletion carriers with neonatal and paediatric pulmonary hypertension by Galambos, Csaba, Mullen, Mary P, Shieh, Joseph T, Schwerk, Nicolaus, Kielt, Matthew J, Ullmann, Nicola, Boldrini, Renata, Stucin-Gantar, Irena, Haass, Cristina, Bansal, Manish, Agrawal, Pankaj B, Johnson, Joyce, Peca, Donatella, Surace, Cecilia, Cutrera, Renato, Pauciulo, Michael W, Nichols, William C, Griese, Matthias, Ivy, Dunbar, Abman, Steven H, Austin, Eric D, Danhaive, Olivier

“…Rare variants in the T-box transcription factor 4 gene ( ) have recently been recognised as an emerging cause of paediatric pulmonary hypertension (PH). Their…”
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Translation Initiator EIF4G1 Mutations in Familial Parkinson Disease by Chartier-Harlin, Marie-Christine, Dachsel, Justus C., Vilariño-Güell, Carles, Lincoln, Sarah J., Leprêtre, Frédéric, Hulihan, Mary M., Kachergus, Jennifer, Milnerwood, Austen J., Tapia, Lucia, Song, Mee-Sook, Le Rhun, Emilie, Mutez, Eugénie, Larvor, Lydie, Duflot, Aurélie, Vanbesien-Mailliot, Christel, Kreisler, Alexandre, Ross, Owen A., Nishioka, Kenya, Soto-Ortolaza, Alexandra I., Cobb, Stephanie A., Melrose, Heather L., Behrouz, Bahareh, Keeling, Brett H., Bacon, Justin A., Hentati, Emna, Williams, Lindsey, Yanagiya, Akiko, Sonenberg, Nahum, Lockhart, Paul J., Zubair, Abba C., Uitti, Ryan J., Aasly, Jan O., Krygowska-Wajs, Anna, Opala, Grzegorz, Wszolek, Zbigniew K., Frigerio, Roberta, Maraganore, Demetrius M., Gosal, David, Lynch, Tim, Hutchinson, Michael, Bentivoglio, Anna Rita, Valente, Enza Maria, Nichols, William C., Pankratz, Nathan, Foroud, Tatiana, Gibson, Rachel A., Hentati, Faycal, Dickson, Dennis W., Destée, Alain, Farrer, Matthew J.

“…Genome-wide analysis of a multi-incident family with autosomal-dominant parkinsonism has implicated a locus on chromosomal region 3q26-q28. Linkage and disease…”
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Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease by Zhu, Na, Welch, Carrie L, Wang, Jiayao, Allen, Philip M, Gonzaga-Jauregui, Claudia, Ma, Lijiang, King, Alejandra K, Krishnan, Usha, Rosenzweig, Erika B, Ivy, D Dunbar, Austin, Eric D, Hamid, Rizwan, Pauciulo, Michael W, Lutz, Katie A, Nichols, William C, Reid, Jeffrey G, Overton, John D, Baras, Aris, Dewey, Frederick E, Shen, Yufeng, Chung, Wendy K

“…Pulmonary arterial hypertension (PAH) is a rare disease characterized by distinctive changes in pulmonary arterioles that lead to progressive pulmonary…”
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Cellular sources of interleukin-6 and associations with clinical phenotypes and outcomes in pulmonary arterial hypertension by Simpson, Catherine E, Chen, Jenny Y, Damico, Rachel L, Hassoun, Paul M, Martin, Lisa J, Yang, Jun, Nies, Melanie, Griffiths, Megan, Vaidya, R Dhananjay, Brandal, Stephanie, Pauciulo, Michael W, Lutz, Katie A, Coleman, Anna W, Austin, Eric D, Ivy, Dunbar D, Nichols, William C, Everett, Allen D

“…The pro-inflammatory cytokine interleukin (IL)-6 has been associated with outcomes in small pulmonary arterial hypertension (PAH) cohorts composed largely of…”
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Genomewide association study for susceptibility genes contributing to familial Parkinson disease by Pankratz, Nathan, Wilk, Jemma B, Latourelle, Jeanne C, DeStefano, Anita L, Halter, Cheryl, Pugh, Elizabeth W, Doheny, Kimberly F, Gusella, James F, Nichols, William C, Foroud, Tatiana, Myers, Richard H

“…Five genes have been identified that contribute to Mendelian forms of Parkinson disease (PD); however, mutations have been found in fewer than 5% of patients,…”
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Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension by Gao, Li, Skinner, John, Nath, Tanmay, Lin, Qing, Griffiths, Megan, Damico, Rachel L, Pauciulo, Michael W, Nichols, William C, Hassoun, Paul M, Everett, Allen D, Johns, Roger A

“…Abnormal remodeling of distal pulmonary arteries in patients with pulmonary arterial hypertension (PAH) leads to progressively increased pulmonary vascular…”
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The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension by Wang, Yuhua, Pandey, Ram Naresh, York, Allen J., Mallela, Jaya, Nichols, William C., Hu, Yueh-Chiang, Molkentin, Jeffery D., Wikenheiser-Brokamp, Kathryn A., Hegde, Rashmi S.

“…In pulmonary hypertension vascular remodeling leads to narrowing of distal pulmonary arterioles and increased pulmonary vascular resistance. Vascular…”
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