Search Results - "Nichols, Nanette F"
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Dopamine D3 Receptor Antagonists. 1. Synthesis and Structure−Activity Relationships of 5,6-Dimethoxy-N-alkyl- and N-Alkylaryl-Substituted 2-Aminoindans
Published in Journal of medicinal chemistry (20-12-2001)“…5,6-Dimethoxy-2-(N-dipropyl)-aminoindan (3, PNU-99194A) was found to be a selective dopamine D3 receptor antagonist with potential antipsychotic properties in…”
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Synthesis and Biological Activities of (R)-5,6-Dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and Its Metabolites
Published in Journal of medicinal chemistry (28-02-1997)“…The imidazoquinoline (R)-5,6-dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine [(R)-3] is a potent dopamine agonist when tested in animals but…”
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2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: New templates for 5-HT2C agonists
Published in Bioorganic & medicinal chemistry letters (21-07-2003)Get full text
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2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: new templates for 5-HT(2C) agonists
Published in Bioorganic & medicinal chemistry letters (21-07-2003)“…The design and synthesis of the novel 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole 5 is described. This azepinoindole has excellent affinity for 5-HT(2C)…”
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2,3,4,5-Tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7- a]indoles: new templates for 5-HT 2C agonists
Published in Bioorganic & medicinal chemistry letters (2003)“…The design and synthesis of the novel 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7- a]indole 5 is described. This azepinoindole has excellent affinity for 5-HT 2C…”
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