Search Results - "Nichols, Lisa"

Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug by Nichols, Lisa A, Adang, Laura A, Kedes, Dean H

“…Infection with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) often results in the development of fatal tumors in immunocompromised patients. Studies of…”
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Advancing data to care strategies for persons with HIV using an innovative reconciliation process by Villanueva, Merceditas, Miceli, Janet, Speers, Suzanne, Nichols, Lisa, Carroll, Constance, Jenkins, Heidi, Altice, Frederick

“…UN AIDS has set ambitious 95-95-95 HIV care continuum targets for global HIV elimination by 2030. The U.S. HIV Care Continuum in 2018 showed that 65% of…”
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Understanding Users’ Engagement in a Provider-Created Mobile App for Training to Advance Hepatitis C Care: Knowledge Assessment Survey Study by Wegener, Maximilian, Sims, Katarzyna, Brooks, Ralph, Nichols, Lisa, Sideleau, Robert, McKay, Sharen, Villanueva, Merceditas

“…Background The World Health Organization and the Centers for Disease Control and Prevention have set ambitious hepatitis C virus (HCV) elimination targets for…”
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Mechanisms of Spatial and Temporal Development of Autoimmune Vitiligo in Tyrosinase-Specific TCR Transgenic Mice by Gregg, Randal K, Nichols, Lisa, Chen, Yiming, Lu, Bao, Engelhard, Victor H

“…Generalized vitiligo is thought to have an autoimmune etiology and has been correlated with the presence of CD8 T cells specific for melanocyte differentiation…”
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Deletional Self-Tolerance to a Melanocyte/Melanoma Antigen Derived from Tyrosinase Is Mediated by a Radio-Resistant Cell in Peripheral and Mesenteric Lymph Nodes by Nichols, Lisa A, Chen, Yiming, Colella, Teresa A, Bennett, Clare L, Clausen, Bjorn E, Engelhard, Victor H

“…Self-tolerance to melanocyte differentiation Ags limits the ability to generate therapeutic antimelanoma responses. However, the mechanisms responsible for CD8…”
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Vitreomacular interface abnormalities in the Ghanaian African by Amoaku, Winfried M., Cushley, Laura, Silvestri, Vittorio, Akafo, Stephen, Amissah-Arthur, Kwesi N., Lartey, Seth, Hageman, Courtney N., Pappas, Christian M., Hubbard, William C., Bernstein, Paul S., Vitale, Albert, Roberts, Megan, Virgili, Gianni, Hageman, Gregory S., Silvestri, Giuliana

“…Background/Objective Describe vitreomacular interface abnormalities (VMIA) using spectral-domain optical coherence tomography (SD-OCT), and correlations with…”
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Associations Between Injection Risk and Community Disadvantage Among Suburban Injection Drug Users in Southwestern Connecticut, USA by Heimer, Robert, Barbour, Russell, Palacios, Wilson R., Nichols, Lisa G., Grau, Lauretta E.

“…Increases in drug abuse, injection, and opioid overdoses in suburban communities led us to study injectors residing in suburban communities in southwestern…”
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Tracking expression and subcellular localization of RNA and protein species using high-throughput single cell imaging flow cytometry by Borah, Sumit, Nichols, Lisa A, Hassman, Lynn M, Kedes, Dean H, Steitz, Joan A

“…We report a high-throughput application of multispectral imaging flow cytometry (MIFC) for analyzing the expression and localization of both RNA and protein…”
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Costs and cost‐effectiveness of a collaborative data‐to‐care intervention for HIV treatment and care in the United States by Shrestha, Ram K., Fanfair, Robyn Neblett, Randall, Liisa M., Lucas, Crystal, Nichols, Lisa, Camp, Nasima, Brady, Kathleen A., Jenkins, Heidi, Altice, Frederick L., DeMaria, Alfred, Villanueva, Merceditas, Weidle, Paul J.

“…Introduction Data‐to‐care programmes utilize surveillance data to identify persons who are out of HIV care, re‐engage them in care and improve HIV care…”
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Incomplete Differentiation of Antigen-Specific CD8 T Cells in Tumor-Draining Lymph Nodes by Hargadon, Kristian M, Brinkman, C. Colin, Sheasley-O'Neill, Stacey L, Nichols, Lisa A, Bullock, Timothy N. J, Engelhard, Victor H

“…CD8 T cells lacking effector activity have been recovered from lymphoid organs of mice and patients with progressing tumors. We explored the basis for lack of…”
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Strategies and challenges in eliciting immunity to melanoma by Ferguson, Andrew R, Nichols, Lisa A, Zarling, Angela L, Thompson, Elizabeth D, Brinkman, C. Colin, Hargadon, Kristian M, Bullock, Timothy N, Engelhard, Victor H

“…The ability of CD8⁺ T cells to recognize melanoma tumors has led to the development of immunotherapeutic approaches that use the antigens CD8⁺ T cells…”
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Engage research institutions on research regulatory reform by Nichols, Lisa, Wynes, David

“…Agencies should consult researchers and administrators on how to cut bureaucratic red tape Concerns about the growth of research regulations and reporting…”
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Perceptions Towards HCV Treatment with Direct Acting Antivirals (DAAs): A Qualitative Analysis with Persons with HIV/HCV Co-infection Who Delay or Refuse Treatment by Brothers, Sarah, DiDomizio, Elizabeth, Nichols, Lisa, Brooks, Ralph, Villanueva, Merceditas

“…In the United States, approximately 25% of people with HIV (PWH) are co-infected with hepatitis C (HCV). Since 2014, highly effective and well-tolerated…”
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Law enforcement perceptions of job stress and barriers to supportive resources when working child sexual abuse cases in the southern United States by Nichols, Lisa, Bowen, Kendra N.

“…PurposeThe purpose of this paper was to examine law enforcement officers' perspectives on job stress and barriers to supportive resources when working child…”
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Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut by Wegener, Maximilian, Brooks, Ralph, Speers, Suzanne, Nichols, Lisa, Villanueva, Merceditas

“…Objectives: Highly effective direct-acting antiviral medications have made it feasible to achieve elimination of hepatis C virus (HCV), including for people…”
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In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift by Kheirolomoom, Azadeh, Kare, Aris J., Ingham, Elizabeth S., Paulmurugan, Ramasamy, Robinson, Elise R., Baikoghli, Mo, Inayathullah, Mohammed, Seo, Jai W., Wang, James, Fite, Brett Z., Wu, Bo, Tumbale, Spencer K., Raie, Marina N., Cheng, R. Holland, Nichols, Lisa, Borowsky, Alexander D., Ferrara, Katherine W.

“…Ex vivo programming of T cells can be efficacious but is complex and expensive; therefore, the development of methods to transfect T cells in situ is…”
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Double emulsion flow cytometry with high-throughput single droplet isolation and nucleic acid recovery by Brower, Kara K, Carswell-Crumpton, Catherine, Klemm, Sandy, Cruz, Bianca, Kim, Gaeun, Calhoun, Suzanne G K, Nichols, Lisa, Fordyce, Polly M

“…Droplet microfluidics has made large impacts in diverse areas such as enzyme evolution, chemical product screening, polymer engineering, and single-cell…”
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Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial by Machavariani, Eteri, Miceli, Janet, Altice, Frederick L, Fanfair, Robyn Neblett, Speers, Suzanne, Nichols, Lisa, Jenkins, Heidi, Villanueva, Merceditas

“…Re-engaging people with HIV who are newly out-of-care remains challenging. Data-to-care (D2C) is a potential strategy to re-engage such individuals. A…”
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Rethinking pediatric trauma triage by Gurien, Lori A., Nichols, Lisa, Williamson, Patsy, Letton, Robert W.

“…Despite advances in the delivery of trauma care, trauma remains the leading cause of death amongst the pediatric population within the United States and is one…”
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OMIP-095: 40-Color spectral flow cytometry delineates all major leukocyte populations in murine lymphoid tissues by Kare, Aris J, Nichols, Lisa, Zermeno, Ricardo, Raie, Marina N, Tumbale, Spencer K, Ferrara, Katherine W

“…High-dimensional immunoprofiling is essential for studying host response to immunotherapy, infection, and disease in murine model systems. However, the…”
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