Search Results - "Nichols, Dave P."

Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic Fibrosis by Nichols, Dave P, Odem-Davis, Katherine, Cogen, Jonathan D, Goss, Christopher H, Ren, Clement L, Skalland, Michelle, Somayaji, Ranjani, Heltshe, Sonya L

“…Chronic azithromycin is commonly used in cystic fibrosis based on short controlled clinical trials showing reductions in pulmonary exacerbations and improved…”
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Cystic fibrosis - Ten promising therapeutic approaches in the current era of care by Somayaji, Ranjani, Nichols, Dave P, Bell, Scott C

“…Cystic fibrosis (CF) is a genetic disease affecting multiple organ systems. Research and innovations in novel therapeutic agents and health care delivery have…”
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Early Aspergillosis in Cystic Fibrosis and Air Trapping: Guilt by Association? by Nichols, Dave P, Moss, Richard B

“…A study that examines early aspergillosis in cystic fibrosis and air trapping is featured. It offers details of the method of the study that observes…”
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Developmental Milestones in Pediatric Research: A Case for Including Efficacy as Part of Interventional Trials in Infants with Cystic Fibrosis by Sanders, Don B, Nichols, Dave P

“…In a study reported in this issue of the Journal, Stahl and colleagues (pp. 1238-1248) provide new evidence for the safety, tolerability, and potential…”
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Recurrent rhinovirus infections in a child with inherited MDA5 deficiency by Lamborn, Ian T, Jing, Huie, Zhang, Yu, Drutman, Scott B, Abbott, Jordan K, Munir, Shirin, Bade, Sangeeta, Murdock, Heardley M, Santos, Celia P, Brock, Linda G, Masutani, Evan, Fordjour, Emmanuel Y, McElwee, Joshua J, Hughes, Jason D, Nichols, Dave P, Belkadi, Aziz, Oler, Andrew J, Happel, Corinne S, Matthews, Helen F, Abel, Laurent, Collins, Peter L, Subbarao, Kanta, Gelfand, Erwin W, Ciancanelli, Michael J, Casanova, Jean-Laurent, Su, Helen C

“…MDA5 is a cytosolic sensor of double-stranded RNA (ds)RNA including viral byproducts and intermediates. We studied a child with life-threatening, recurrent…”
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Developing Inhaled Antibiotics in Cystic Fibrosis: Current Challenges and Opportunities by Nichols, Dave P, Durmowicz, Anthony G, Field, Ann, Flume, Patrick A, VanDevanter, Donald R, Mayer-Hamblett, Nicole

“…P. aeruginosa, in particular, is linked to greater airway inflammation and overall decline in health (4, 5). Because of this, strategies to administer…”
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PROMISE: Working with the CF community to understand emerging clinical and research needs for those treated with highly effective CFTR modulator therapy by Nichols, Dave P., Donaldson, Scott H., Frederick, Carla A., Freedman, Steven D., Gelfond, Daniel, Hoffman, Lucas R., Kelly, Andrea, Narkewicz, Michael R., Pittman, Jessica E., Ratjen, Felix, Sagel, Scott D., Rosenfeld, Margaret, Schwarzenberg, Sarah Jane, Singh, Pradeep K., Solomon, George M., Stalvey, Michael S., Kirby, Shannon, VanDalfsen, Jill M., Clancy, John P., Rowe, Steven M.

“…•PROMISE is a large clinical study to measure the impact of ETI by clinical use.•This observational study will measure outcomes over the first two years of…”
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Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis by Nichols, Dave P, Happoldt, Carrie L, Bratcher, Preston E, Caceres, Silvia M, Chmiel, James F, Malcolm, Kenneth C, Saavedra, Milene T, Saiman, Lisa, Taylor-Cousar, Jennifer L, Nick, Jerry A

“…Abstract Background Concomitant use of oral azithromycin and inhaled tobramycin occurs in approximately half of US cystic fibrosis (CF) patients. Recent data…”
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Long-term azithromycin use is not associated with QT prolongation in children with cystic fibrosis by Magaret, Amalia S., Salerno, Jack, Deen, Jason F., Kloster, Margaret, Mayer-Hamblett, Nicole, Ramsey, Bonnie W., Nichols, Dave P.

“…•Long-term trial of chronic azithromycin in children with CF and P. aeruginosa.•Cardiovascular health was measured using electrocardiogram.•Thrice weekly…”
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Oral Azithromycin Use and the Recovery of Lung Function from Pulmonary Exacerbations Treated with Intravenous Tobramycin or Colistimethate in Adults with Cystic Fibrosis by Somayaji, Ranjani, Russell, Renee, Cogen, Jonathan D, Goss, Cristopher H, Nick, Sarah E, Saavedra, Milene T, Taylor-Cousar, Jennifer L, Nick, Jerry A, Nichols, Dave P

“…The potential of azithromycin to alter the antimicrobial and clinical benefits of inhaled tobramycin in patients with cystic fibrosis (CF) has been previously…”
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Assessment of Bacterial Colonization in Airways of Children with Asthma and Chronic Cough by Culture and 16S rRNA Gene Sequencing by Hauk, Pia J., MD, Goleva, Elena, PhD, Jackson, Leisa P., BS, Harris, J. Kirk, PhD, Olin, J. Tod, MD, MSCS, Brugman, Susan M., MD, Nichols, Dave P., MD, Krawiec, Marzena, MD, Leung, Donald Y., MD, PhD

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On the Origin of Lung Cancers by Pennycuick, Adam, Janes, Sam M

“…A study that examines the early changes of lungs that can lead to cancerous transformation. It offers details of the method of the study that uses genomic…”
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