Search Results - "Nicholls, Joanna"

Endoscopically applied radiofrequency ablation appears to be safe in the treatment of malignant biliary obstruction by Steel, Alan W., MD, MRCP, Postgate, Aymer J., MD, MRCP, Khorsandi, Shirin, MRCS, Nicholls, Joanna, MSc, Jiao, Long, FRCS, Vlavianos, Pangiotis, MD, Habib, Nagy, FRCS, Westaby, David, MA, FRCP

“…Background In unresectable malignant bile duct obstruction in a patient with a life expectancy longer than 3 months, the use of self-expandable metal stents…”
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RNA Activation-A Novel Approach to Therapeutically Upregulate Gene Transcription by Tan, Choon Ping, Sinigaglia, Laura, Gomez, Valentí, Nicholls, Joanna, Habib, Nagy A

“…RNA activation (RNAa) is a mechanism whereby RNA oligos complementary to genomic sequences around the promoter region of genes increase the transcription…”
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Anaerobic Ammonium Oxidation Measured in Sediments along the Thames Estuary, United Kingdom by TRIMMER, Mark, NICHOLLS, Joanna C, DEFLANDRE, Bruno

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Intra‐Arterial Immunoselected CD34+ Stem Cells for Acute Ischemic Stroke by Banerjee, Soma, Bentley, Paul, Hamady, Mohammad, Marley, Stephen, Davis, John, Shlebak, Abdul, Nicholls, Joanna, Williamson, Deborah A., Jensen, Steen L., Gordon, Myrtle, Habib, Nagy, Chataway, Jeremy

“…In the first study of human subjects, the safety and feasibility of treatment with CD34+ cells delivered intra‐arterially in patients with acute ischemic…”
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Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo by Reebye, Vikash, Sætrom, Pål, Mintz, Paul J., Huang, Kai‐Wen, Swiderski, Piotr, Peng, Ling, Liu, Cheng, Liu, Xiaoxuan, Lindkær‐Jensen, Steen, Zacharoulis, Dimitris, Kostomitsopoulos, Nikolaos, Kasahara, Noriyuki, Nicholls, Joanna P., Jiao, Long R., Pai, Madhava, Spalding, Duncan R., Mizandari, Malkhaz, Chikovani, Tinatin, Emara, Mohamed M., Haoudi, Abdelali, Tomalia, Donald A., Rossi, John J., Habib, Nagy A.

“…Hepatocellular carcinoma (HCC) occurs predominantly in patients with liver cirrhosis. Here we show an innovative RNA‐based targeted approach to enhance…”
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Production of Nitrogen Gas via Anammox and Denitrification in Intact Sediment Cores along a Continental Shelf to Slope Transect in the North Atlantic by Trimmer, Mark, Nicholls, Joanna Claire

“…We measured the production of N₂ gas from anammox and denitrification simultaneously in intact sediment cores at six sites along a transect of the continental…”
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Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34+ Cells Into Patients With Alcoholic Liver Cirrhosis by PAI, Madhava, ZACHAROULIS, Dimitris, GLIBETIC, Maria, BANSI, Devinder, KHAN, Shahid A, KYRIAKOU, Despina, ROUNTAS, Christos, THILLAINAYAGAM, Andrew, NICHOLLS, Joanna P, JENSEN, Steen, APPERLEY, Jane F, GORDON, Myrtle Y, MILICEVIC, Miroslav N, HABIB, Nagy A, HELMY, Salah, JIAO, Long R, LEVICAR, Natasa, TAIT, Paul, SCOTT, Michael, MARLEY, Stephen B, JESTICE, Kevin

“…Recent advances in regenerative medicine, including hematopoietic stem cell (HSC) transplantation, have brought hope for patients with severe alcoholic liver…”
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Characterization and Clinical Application of Human CD34+ Stem/Progenitor Cell Populations Mobilized into the Blood by Granulocyte Colony‐Stimulating Factor by Gordon, Myrtle Y., Levičar, Nataša, Pai, Madhava, Bachellier, Philippe, Dimarakis, Ioannis, Al‐Allaf, Faisal, M'Hamdi, Hanane, Thalji, Tamara, Welsh, Jonathan P., Marley, Stephen B., Davies, John, Dazzi, Francesco, Marelli‐Berg, Federica, Tait, Paul, Playford, Raymond, Jiao, Long, Jensen, Steen, Nicholls, Joanna P., Ayav, Ahmet, Nohandani, Mahrokh, Farzaneh, Farzin, Gaken, Joop, Dodge, Rikke, Alison, Malcolm, Apperley, Jane F., Lechler, Robert, Habib, Nagy A.

“…A phase I study was performed to determine the safety and tolerability of injecting autologous CD34+ cells into five patients with liver insufficiency. The…”
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MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial by Sarker, Debashis, Plummer, Ruth, Meyer, Tim, Sodergren, Mikael H, Basu, Bristi, Chee, Cheng Ean, Huang, Kai-Wen, Palmer, Daniel H, Ma, Yuk Ting, Evans, T R Jeff, Spalding, Duncan R C, Pai, Madhava, Sharma, Rohini, Pinato, David J, Spicer, James, Hunter, Sarah, Kwatra, Vineet, Nicholls, Joanna P, Collin, David, Nutbrown, Robert, Glenny, Helen, Fairbairn, Sonia, Reebye, Vikash, Voutila, Jon, Dorman, Stephanie, Andrikakou, Pinelopi, Lloyd, Peter, Felstead, Steve, Vasara, Jenni, Habib, Robert, Wood, Chris, Saetrom, Pal, Huber, Hans E, Blakey, David C, Rossi, John J, Habib, Nagy

“…Transcription factor C/EBP-α (CCAAT/enhancer-binding protein alpha) acts as a master regulator of hepatic and myeloid functions and multiple oncogenic…”
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Direct measurement of anaerobic ammonium oxidation (anammox) and denitrification in intact sediment cores by Trimmer, Mark, Risgaard-Petersen, Nils, Nicholls, Joanna C., Engström, Pia

“…Anammox, i.e. the anaerobic oxidation of NH₄⁺ with NO₂⁻ to N₂, has redefined our understanding of nitrogen cycling in aquatic ecosystems. The isotope pairing…”
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Biphasic Behavior of Anammox Regulated by Nitrite and Nitrate in an Estuarine Sediment by Trimmer, Mark, Nicholls, Joanna C, Morley, Nicholas, Davies, Christian A, Aldridge, John

“…The production of N₂ gas via anammox was investigated in sediment slurries at in situ NO₂⁻ concentrations in the presence and absence of NO₃⁻. With single…”
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Comparison of ladderane phospholipid and core lipids as indicators for anaerobic ammonium oxidation (anammox) in marine sediments by Jaeschke, Andrea, Rooks, Christine, Trimmer, Mark, Nicholls, Joanna C., Hopmans, Ellen C., Schouten, Stefan, Sinninghe Damsté, Jaap S.

“…We investigated anaerobic ammonium oxidation (anammox) in continental shelf and slope sediments of the Irish and Celtic Seas by using anammox specific…”
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Vaccination of Colorectal Cancer Patients with Modified Vaccinia Ankara Encoding the Tumor Antigen 5T4 (TroVax) Given Alongside Chemotherapy Induces Potent Immune Responses by Harrop, Richard, Drury, Noel, Shingler, William, Chikoti, Priscilla, Redchenko, Irina, Carroll, Miles W, Kingsman, Susan M, Naylor, Stuart, Melcher, Alan, Nicholls, Joanna, Wassan, Harpreet, Habib, Nagy, Anthoney, Alan

“…Purpose: The attenuated strain of vaccinia virus, modified vaccinia Ankara (MVA) encoding the tumor antigen 5T4 (TroVax), has been evaluated in an open-label…”
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A perspective on non-catalytic Src homology (SH) adaptor signalling proteins by Reebye, Vikash, Frilling, Andrea, Hajitou, Amin, Nicholls, Joanna P., Habib, Nagy A., Mintz, Paul J.

“…Intracellular adaptor signalling proteins are members of a large family of mediators crucial for signal transduction pathways. Structurally, these molecules…”
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New technique for liver resection using heat coagulative necrosis by WEBER, Jean-Christophe, NAVARRA, Giuseppe, JIAO, Long R, NICHOLLS, Joanna P, JENSEN, Steen Lindkaer, HABIB, Nagy A

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High frequency of fetal cells within a primitive stem cell population in maternal blood by Mikhail, Magued A., M’Hamdi, Hanane, Welsh, Jonathan, Levičar, Nataša, Marley, Stephen B., Nicholls, Joanna P., Habib, Nagy A., Louis, Louay S., Fisk, Nicholas M., Gordon, Myrtle Y.

“…BACKGROUND During pregnancy, fetal cells enter the maternal bloodstream resulting in fetal cell microchimerism. The fetal cells persist in the mother for…”
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Pilot study for a new bipolar radiofrequency ablation/aspirator device in the management of primary and secondary liver cancers by Zacharoulis, Dimitris, Khorsandi, Shirin E., Vavra, Petr, Dostalik, Jan, Navarra, Giuseppe, Nicholls, Joanna P., Jiao, Long R., Habib, Nagy A.

“…Background: In the US, the thermal ablation workload for cancer involving the liver is predicted to more than double in the next 5 years, emphasising the need…”
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A Multicenter Phase I Gene Therapy Clinical Trial Involving Intraperitoneal Administration of E1A-Lipid Complex in Patients with Recurrent Epithelial Ovarian Cancer Overexpressing HER-2/neu Oncogene by MADHUSUDAN, Srinivasan, TAMIR, Ayala, CHARNOCK, Mark, HABIB, Nagy A, LECHLER, Robert, NICHOLLS, Joanna, PIGNATELLI, Massimo, GANESAN, Trivadi S, BATES, Nicholas, FLANAGAN, Elizabeth, GORE, Martin E, BARTON, Desmond P. J, HARPER, Peter, SECKL, Michael, THOMAS, Hilary, LEMOINE, Nicholas R

“…Purpose: HER-2/ neu oncogene is overexpressed in 10–30% of epithelial ovarian cancers and is associated with a poor prognosis. The E1A gene product of…”
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MicroRNA-181a Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood by Mintz, Paul J, Sætrom, Pål, Reebye, Vikash, Lundbæk, Marie B, Lao, Kaiqin, Rossi, John J, Gaensler, Karin ML, Kasahara, Noriyuki, Nicholls, Joanna P, Jensen, Steen, Haoudi, Abdelali, Emara, Mohamed M, Gordon, Myrtle YA, Habib, Nagy A

“…Exploiting the properties of stem cells by microRNA (miRNA) profiling offers an attractive approach to identify new regulators of stem cell fate. Although…”
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A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34+ Cells by Reebye, Vikash, Sætrom, Pål, Mintz, Paul J, Rossi, John J, Kasahara, Noriyuki, Nteliopoulos, Georgios, Nicholls, Joanna, Haoudi, Abdelali, Gordon, Myrtle, Habib, Nagy A

“…Upon functional loss of insulin producing islet β-cells, some patients with diabetes become dependent on life-long insulin supplementation therapy…”
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