Search Results - "Nicholls, Flora"
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Comparison of medetomidine, thiopental and ketamine/midazolam anesthesia in chick embryos for in ovo Magnetic Resonance Imaging free of motion artifacts
Published in Scientific reports (23-10-2015)“…Non-invasive assessment of the perfusion capacity of tissue engineered constructs grown on the chorioallantoic membrane by MRI is often hampered by motion…”
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Burrowing behavior as an indicator of post-laparotomy pain in mice
Published in Frontiers in behavioral neuroscience (12-10-2010)“…Detection of persistent pain of a mild-to-moderate degree in laboratory mice is difficult because mice do not show unambiguous symptoms of pain or suffering…”
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HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats
Published in PloS one (30-06-2015)“…HLA-B27 is a common genetic risk factor for the development of Spondyloarthritides (SpA). HLA-B27 can misfold to form cell-surface heavy chain homodimers…”
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Transplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Due to its similarity of skin anatomy and physiology, the pig appears to be a well-suited animal model for preclinical studies of skin analog transplantations…”
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Isoflurane and sevoflurane provide equally effective anaesthesia in laboratory mice
Published in Laboratory animals (London) (01-10-2010)“…Isoflurane is currently the most common volatile anaesthetic used in laboratory mice, whereas in human medicine the more modern sevoflurane is often used for…”
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Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression
Published in Scientific reports (28-11-2017)“…Trichuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (IBD) yet understanding of the underlying mechanisms and…”
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Coronary optical frequency domain imaging (OFDI) for in vivo evaluation of stent healing: comparison with light and electron microscopy
Published in European heart journal (01-07-2010)“…Aims Coronary late stent thrombosis, a rare but devastating complication, remains an important concern in particular with the increasing use of drug-eluting…”
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Biological Flora of Central Europe: Baldellia ranunculoides (Alismataceae)
Published in Perspectives in plant ecology, evolution and systematics (01-05-2008)“…Baldellia ranunculoides (L.) Parl. (Alismataceae) is a taxonomically problematic aquatic plant with an historically ill-defined distribution and global…”
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Three-Dimensional Printed Hydroxyapatite Bone Substitutes Designed by a Novel Periodic Minimal Surface Algorithm Are Highly Osteoconductive
Published in 3D printing and additive manufacturing (01-10-2023)“…Autologous bone remains the gold standard bone substitute in clinical practice. Therefore, the microarchitecture of newly developed synthetic bone substitutes,…”
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Oral administration of dextran sodium sulphate induces a caecum-localized colitis in rabbits
Published in International journal of experimental pathology (01-06-2015)“…Summary Trichuris suis ova (TSO) have shown promising results in the treatment of inflammatory bowel disease (IBD) but the mechanisms which underlies this…”
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Combining Sevoflurane Anesthesia with Fentanyl-Midazolam or S-Ketamine in Laboratory Mice
Published in Journal of the American Association for Laboratory Animal Science (01-03-2012)“…Laboratory mice typically are anesthetized by either inhalation of volatile anesthetics or injection of drugs. Here we compared the acute and postanesthetic…”
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2D motion analysis of rabbits after Achilles tendon rupture repair and histological analysis of extracted tendons: Can the number of animals be reduced by operating both hind legs simultaneously?
Published in Injury (01-10-2013)“…Abstract Background Considering the 3Rs principle in animal experiments, there is a demand to perform research experiments with the fewest number of animals…”
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Echinomycin did not affect the safety of fracture healing: an experimental pilot study on a murine femur fracture model
Published in Patient safety in surgery (16-02-2016)“…There is a need for effective drugs in the prevention and treatment of heterotopic ossifications (HO) after fractures. Echinomycin has been shown to prevent…”
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Human miR223 promoter as a novel myelo-specific promoter for chronic granulomatous disease gene therapy
Published in Human gene therapy. Part B. Methods (01-06-2013)“…Targeting transgene expression to specific hematopoietic cell lineages could contribute to the safety of retroviral vectors in gene therapeutic applications…”
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HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats: e0130811
Published in PloS one (01-06-2015)“…Objectives HLA-B27 is a common genetic risk factor for the development of Spondyloarthritides (SpA). HLA-B27 can misfold to form cell-surface heavy chain…”
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Analgesia in clinically relevant rodent models of sepsis
Published in Laboratory animals (London) (01-12-2016)“…Postoperative analgesia in rodent sepsis models has been considerably neglected in the past. However, intentions to model clinical practice, increasing…”
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