Search Results - "Nicholls, D. P."

Spectral Stability of Deep Two-Dimensional Gravity-Capillary Water Waves by Akers, B., Nicholls, D. P.

“…In this contribution we study the spectral stability problem for periodic traveling gravity‐capillary waves on a two‐dimensional fluid of infinite depth. We…”
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Controlling the size and alignment of ZnO microrods using ZnO thin film templates deposited by pulsed laser ablation by HENLEY, S. J, ASHFOLD, M. N. R, NICHOLLS, D. P, WHEATLEY, P, CHERNS, D

“…The production of dense arrays of well aligned ZnO nano- and microrods with a controllable distribution of diameters is demonstrated. The rods were grown using…”
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Multiplex MassARRAY spectrometry (iPLEX) produces a fast and economical test for 56 familial hypercholesterolaemia-causing mutations by Wright, WT, Heggarty, SV, Young, IS, Nicholls, DP, Whittall, R, Humphries, SE, Graham, CA

“…Familial hypercholesterolaemia (FH) is a common single gene disorder, pre‐disposing to cardiovascular disease, which is most commonly caused by mutations in…”
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Statin safety and chronic liver disease by Cash, J, Callender, M E, McDougall, N I, Young, I S, Nicholls, D P

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Diagnosis of heterozygous familial hypercholesterolaemia in children by Nicholls, D P, Cather, M, Byrne, C, Graham, C A, Young, I S

“…Most children with familial hypercholesterolaemia (FH) are diagnosed by raised blood cholesterol levels, but the test lacks sensitivity and specificity. As…”
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Polarity determination of zinc oxide nanorods by defocused convergent-beam electron diffraction by Nicholls, D. P., Vincent, R., Cherns, D., Sun, Y., Ashfold, M. N. R.

“…The crystal polarity of wurtzite zinc oxide nanorods grown hydrothermally parallel to the c = [0001] direction has been determined by convergent-beam electron…”
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The effect of the neutral endopeptidase inhibitor drug, candoxatril, on circulating levels of two of the most potent vasoactive peptides by McDowell, G., Coutie, W., Shaw, C., Buchanan, K. D., Struthers, A. D., Nicholls, D. P.

“…Aims Candoxatril is a specific neutral endopeptidase (NEP) 24.11 inhibitor, and previous work has documented the effect of NEP inhibition on atrial and brain…”
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Nutritional intake and oxidative stress in chronic heart failure by Hughes, C.M, Woodside, J.V, McGartland, C, Roberts, M.J, Nicholls, D.P, McKeown, P.P

“…Abstract Background and aims Patients with chronic heart failure (CHF) are known to be at risk of malnutrition, and cardiac cachexia is an adverse prognostic…”
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B-type natriuretic peptide as a screening test for patients undergoing echocardiography to determine left ventricular dysfunction by Donnelly, R., Carl, I., Hughes, C., Auld, P., Nicholls, D.P.

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Effect of thoracotomy and lung resection on exercise capacity in patients with lung cancer by Nugent, A-M, Steele, I C, Carragher, A M, McManus, K, McGuigan, J A, Gibbons, J R P, Riley, M S, Nicholls, D P

“…BACKGROUND Resection is the treatment of choice for lung cancer, but may cause impaired cardiopulmonary function with an adverse effect on quality of life. Few…”
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Variability of Nt-proANP and C-ANP by McDowell, G., Patterson, C., Maguire, S., Shaw, C., Nicholls, D. P., Hall, C.

“…Background Natriuretic peptides are frequently measured in patients with chronic cardiac failure (CCF). We set out to compare the variability of atrial…”
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Abnormal vascular responses in human chronic cardiac failure are both endothelium dependent and endothelium independent by Maguire, S M, Nugent, A G, McGurk, C, Johnston, G D, Nicholls, D P

“…Objective To study underlying vascular responses in chronic heart failure in patients without ACE inhibitor treatment, and to compare them with age matched…”
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Oxygen consumption is increased relative to work rate in patients with McArdle's disease by O'Dochartaigh, C. S., Ong, H. Y., Lovell, S. M., Riley, M. S., Patterson, V. H., Young, I. S., Nicholls, D. P.

“…Background  Patients with McArdle's disease suffer exercise incapacity as a result of myophosphorylase deficiency, and for a given work rate have excessive…”
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Aerobic work capacity in patients with chronic fatigue syndrome by Riley, M S, O'Brien, C J, McCluskey, D R, Bell, N P, Nicholls, D P

“…OBJECTIVE--To determine the aerobic work capacity of patients with the chronic fatigue syndrome and compare it with that of two control groups, and to assess…”
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Paraoxonase polymorphisms are not associated with cardiovascular risk in renal transplant recipients by Hasselwander, Oliver, Savage, David A., Mcmaster, Dorothy, Loughrey, Clodagh M., Mcnamee, Peter T., Middleton, Derek, Nicholls, D. Paul, Maxwell, A. Peter, Young, Ian S.

“…Paraoxonase polymorphisms are not associated with cardiovascular risk in renal transplant recipients. Paraoxonase (PON1) gene variants have been identified as…”
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Responses of atrial natriuretic peptide and brain natriuretic peptide to exercise in patients with chronic heart failure and normal control subjects by STEELE, I. C., McDOWELL, G., MOORE, A., CAMPBELL, N. P. S., SHAW, C., BUCHANAN, K. D., NICHOLLS, D. P.

“…Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are known to be elevated in patients with chronic heart failure at rest. While it is known…”
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Oxygen consumption during corridor walk testing in chronic cardiac failure by Riley, M, McParland, J, Stanford, C F, Nicholls, D P

“…We have examined the use of a 6-min corridor walk test in the assessment of functional capacity in 16 patients with chronic cardiac failure. VO2 was determined…”
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HDL composition and HDL antioxidant capacity in patients on regular haemodialysis by Hasselwander, O., McEneny, J., McMaster, D., Fogarty, D.G., Nicholls, D.P., Maxwell, A.P., Young, I.S.

“…Recent evidence suggests that HDL can directly inhibit LDL oxidation, a key early stage in atherogenesis. Patients with chronic renal failure are at increased…”
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Neuropeptide secretion in exercise by Onuoha, G.N, Nicholls, D.P, Patterson, A, Beringer, T

“…Plasma concentrations of atrial natriuretic peptide immunoreactivity (irANP) and brain natriuretic peptide immunoreactivity (irBNP) in elderly normal subjects…”
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Mutation screening and genotype:phenotype correlation in familial hypercholesterolaemia by Graham, Colin A., McClean, Elizabeth, Ward, Alana J.M., Beattie, E.Diane, Martin, Sonya, O’Kane, Maurice, Young, Ian S., Nicholls, D.Paul

“…The aim of this study was to develop a mutation screening protocol for familial hypercholesterolaemia (FH) patients and to assess genotype/phenotype effects in…”
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