Search Results - "Nicholas, Nicole D"

Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models by Li, Fu, Emmerton, Kim K, Jonas, Mechthild, Zhang, Xinqun, Miyamoto, Jamie B, Setter, Jocelyn R, Nicholas, Nicole D, Okeley, Nicole M, Lyon, Robert P, Benjamin, Dennis R, Law, Che-Leung

“…Antibody-drug conjugates (ADC) comprise targeting antibodies armed with potent small-molecule payloads. ADCs demonstrate specific cell killing in clinic, but…”
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Antibody-conjugated drug assay for protease-cleavable antibody-drug conjugates by Sanderson, Russell J, Nicholas, Nicole D, Baker Lee, Cassandra, Hengel, Shawna Mae, Lyon, Robert P, Benjamin, Dennis R, Alley, Stephen C

“…Antibody-drug conjugates (ADCs) require multiple assays to characterize their PK. These assays can separately evaluate the ADC by quantifying the antibody or…”
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A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology by Jeffrey, Scott C, Burke, Patrick J, Lyon, Robert P, Meyer, David W, Sussman, Django, Anderson, Martha, Hunter, Joshua H, Leiske, Chris I, Miyamoto, Jamie B, Nicholas, Nicole D, Okeley, Nicole M, Sanderson, Russell J, Stone, Ivan J, Zeng, Weiping, Gregson, Stephen J, Masterson, Luke, Tiberghien, Arnaud C, Howard, Philip W, Thurston, David E, Law, Che-Leung, Senter, Peter D

“…A highly cytotoxic DNA cross-linking pyrrolobenzodiazepine (PBD) dimer with a valine-alanine dipeptide linker was conjugated to the anti-CD70 h1F6 mAb either…”
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External Rotation Strengthening With Manual Distraction for Individuals With Glenohumeral Osteoarthritis by Nicholas, Nicole D, Ambler, Steven B

“…Osteoarthritis can lead to movement limitations, which are a barrier for strength training. In some instances where improved strength is known to decrease…”
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