Search Results - "Nicholas, Anne"

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva by Lees-Shepard, John B., Yamamoto, Masakazu, Biswas, Arpita A., Stoessel, Sean J., Nicholas, Sarah-Anne E., Cogswell, Cathy A., Devarakonda, Parvathi M., Schneider, Michael J., Cummins, Samantha M., Legendre, Nicholas P., Yamamoto, Shoko, Kaartinen, Vesa, Hunter, Jeffrey W., Goldhamer, David J.

“…Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disorder characterized by progressive and profoundly disabling heterotopic…”
Get full text

Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity by Lees-Shepard, John B, Nicholas, Sarah-Anne E, Stoessel, Sean J, Devarakonda, Parvathi M, Schneider, Michael J, Yamamoto, Masakazu, Goldhamer, David J

“…Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by debilitating heterotopic ossification (HO). The retinoic acid receptor…”
Get full text

Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions by Hensel, Jessica A., Nicholas, Sarah-Anne E., Kimble, Amy L., Nagpal, Arjun S., Omar, Omar M. F., Tyburski, Jordan D., Jellison, Evan R., Ménoret, Antoine, Ozawa, Manabu, Rodriguez-Oquendo, Annabelle, Vella, Anthony T., Murphy, Patrick A.

“…NF-κB–mediated endothelial activation drives leukocyte recruitment and atherosclerosis, in part through adhesion molecules Icam1 and Vcam1. The endothelium is…”
Get full text

A method for rapid flow-cytometric isolation of endothelial nuclei and RNA from archived frozen brain tissue by Kimble, Amy L., Silva, Jordan, Omar, Omar M., Murphy, Melissa, Hensel, Jessica A., Nicholas, Sarah-Anne E., Jellison, Evan R., Reese, Bo, Murphy, Patrick A.

“…Endothelial cells are important contributors to brain development, physiology, and disease. Although RNA sequencing has contributed to the understanding of…”
Get full text

Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci by Xu, Maria M, Ménoret, Antoine, Nicholas, Sarah-Anne E, Günther, Sebastian, Sundberg, Eric J, Zhou, Beiyan, Rodriguez, Annabelle, Murphy, Patrick A, Vella, Anthony T

“…Effector CD8 T cells infiltrate atherosclerotic lesions and are correlated with cardiovascular events, but the mechanisms regulating their recruitment and…”
Get more information

Alternative Splicing of FN (Fibronectin) Regulates the Composition of the Arterial Wall Under Low Flow by Murphy, Patrick A., Jailkhani, Noor, Nicholas, Sarah-Anne, Del Rosario, Amanda M., Balsbaugh, Jeremy L., Begum, Shahinoor, Kimble, Amy, Hynes, Richard O.

“…OBJECTIVE:Exposure of the arterial endothelium to low and disturbed flow is a risk factor for the erosion and rupture of atherosclerotic plaques and aneurysms…”
Get full text

Abstract 333: Endothelial RNA-binding Protein Elavl1 (HuR) Regulates Post-transcriptional Regulation Of Genes Involved In Immune Responses To Increase Cd8 T Cells In The Atherosclerotic Intima by Nicholas, Sarah-Anne E, Hensel, Jessica, Kimble, Amy, Menoret, Antoine, Jellison, Evan R, Reese, Bo, Zhou, Beiyan, Rodriguez, Annabelle, Vella, Anthony, Murphy, Patrick A

“…Abstract only Under low and disturbed flow (LDF), endothelial cells (ECs) covering atherosclerotic lesions influence plaque composition by regulating immune…”
Get full text

Abstract 516: Splice Factor Polypyrimidine Tract-binding Protein 1 (PTBP1) Primes Endothelial Inflammation In Atherogenic Disturbed Flow Conditions by Hensel, Jessica, Nicholas, Sarah-Anne, Omar, Omar, Kimble, Amy, Nagpal, Arjun, Menoret, Antoine, Jellison, Evan R, Rodriguez, Annabelle, Ozawa, Manabu, Vella, Anthony, Murphy, Patrick A

“…NFκB mediated endothelial activation drives leukocyte recruitment and atherosclerosis, in part through upregulation of adhesion molecules Icam1 and Vcam. The…”
Get full text

Alternative Splicing of Fibronectin Regulates the Composition of the Arterial Wall Under Low Flow by Murphy, Patrick A., Jailkhani, Noor, Nicholas, Sarah-Anne, Del Rosario, Amanda M., Balsbaugh, Jeremy L., Begum, Shahinoor, Kimble, Amy, Hynes, Richard O.

Get full text

A method for rapid flow-cytometric isolation of endothelial nuclei and RNA from archived frozen brain tissue by Kimble, Amy L, Silva, Jordan, Omar, Omar M, Murphy, Melissa, Hensel, Jessica A, Nicholas, Sarah-Anne E, Jellison, Evan R, Reese, Bo, Murphy, Patrick A

“…Endothelial cells are important contributors to brain development, physiology, and disease. Although RNA sequencing has contributed to the understanding of…”
Get full text

Clinical and antimicrobial effects of a single episode of subgingival irrigation with tetracycline HCl or chlorhexidine in deep periodontal pockets by Stabholz, A, Nicholas, A A, Zimmerman, G J, Wikesjö, U M

“…15 adults, each providing 4 non-adjacent untreated periodontal pockets with a probing depth (PD) exceeding 6 mm, volunteered for a randomized, split-mouth,…”
Get full text

The effect of a Picture Archiving and Communications System (PACS) on diagnostic performance in the accident and emergency department by Weatherburn, Gwyn, Bryan, Stirling, Nicholas, Anne, Cocks, Robert

“…Objective—A study has been conducted to identify the benefits to the accident and emergency (A&E) department of a hospital wide Picture Archiving and…”
Get full text

Clinical and antimicrobial effects of a single episode of subgingival irrigation with tetracycline HCI or chlorhexidine in deep periodontal pockets by Stabholz, Ayala, Nicholas, Anne A., Zimmerman, Grenith J., Wikesjö, Ulf M. E.

“… 15 adults, each providing 4 non‐adjacent untreated periodontal pockets with a probing depth (PD) exceeding 6 mm. volunteered for a randomized, split‐mouth,…”
Get full text

Successful aging and nutrition / Comment by Anne-Sophie, Nicholas, Andrieu, Sandrine, Nourhashemi, Fati, Rolland, Yves

“…Until recently, aging-related decline was thought of as inevitable, a view based on national and community-based statistics showing that aging is associated…”
Get full text

Nutritional studies on the entrants to an old people's home, with particular reference to folic-acid deficiency by Read, A. E., Gough, K. R., Pardoe, J. L., Nicholas, A.

Get full text