Search Results - "Niavarani, Ahmadreza"
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The role of distinct APOBEC/ADAR mRNA levels in mutational signatures linked to aging and ultraviolet radiation
Published in Scientific reports (04-07-2024)“…The APOBEC/AID family is known for its mutator activity, and recent evidence also supports the potential impact of ADARs. Furthermore, the mutator impacts of…”
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SARS-CoV-2 antibody seroprevalence in the general population and high-risk occupational groups across 18 cities in Iran: a population-based cross-sectional study
Published in The Lancet infectious diseases (01-04-2021)“…Rapid increases in cases of COVID-19 were observed in multiple cities in Iran towards the start of the pandemic. However, the true infection rate remains…”
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APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts
Published in PloS one (25-03-2015)“…Classic deamination mRNA changes, including cytidine to uridine (C-to-U) and adenosine to inosine (A-to-I), are important exceptions to the central dogma and…”
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Seroprevalence of SARS-CoV-2 antibody among urban Iranian population: findings from the second large population-based cross-sectional study
Published in BMC public health (23-05-2022)“…The first large serosurvey in Iran found a SARS-CoV-2 antibody seroprevalence of 17.1% among the general population in the first wave of the epidemic by April,…”
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Dynamics of the COVID-19 Clinical Findings and the Serologic Response
Published in Frontiers in microbiology (07-10-2021)“…The factors affecting the dynamics of lengthening of symptoms and serologic responses are not well known. In order to see how the serologic responses change in…”
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Molecular dynamics analysis predicts ritonavir and naloxegol strongly block the SARS-CoV-2 spike protein-hACE2 binding
Published in Journal of biomolecular structure & dynamics (04-03-2022)“…The rapid emergence of COVID-19 pandemics has posed humans particularly vulnerable to the novel SARS-CoV-2 virus. Since de novo drug discovery is both…”
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Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence
Published in Nature genetics (01-11-2021)“…Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that is not fully explained by known lifestyle and environmental risk…”
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Pancancer analysis identifies prognostic high-APOBEC1 expression level implicated in cancer in-frame insertions and deletions
Published in Carcinogenesis (New York) (08-03-2018)“…Indels are infrequent, but of both functional and prognostic impact in cancers. Pancancer multiplatform analysis identified APOBEC1 and its Variant 3…”
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Abstract 1318: APOBEC/ADAR aberrations are potentially implicated in certain pancancer hypermutation patterns
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Known endogenous mutators include certain APOBEC family members, whose mRNA levels have been implicated in various cancers. Other…”
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Abstract 1319: Distinct pancancer mutational signatures are determined by APOBEC/ADAR aberrations
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Known endogenous mutators include certain APOBEC family member, whose mRNA levels have been implicated in various cancers. Other important…”
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The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia
Published in Annals of hematology (01-01-2016)“…The single-nucleotide polymorphism (SNP) within Wilms tumor-1 ( WT1 ) exon 7, rs16754, has been arguably reported to be implicated in acute myeloid leukemia…”
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A 4‐gene expression score associated with high levels of Wilms Tumor‐1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia
Published in British journal of haematology (01-02-2016)“…Summary Wilms Tumor‐1 (WT1) expression level is implicated in the prognosis of acute myeloid leukaemia (AML). We hypothesized that a gene expression profile…”
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A 16-Gene Signature Associated with High Levels of Wilms Tumor-1 (WT1) Expression Is an Adverse Prognostic Factor in Acute Myeloid Leukemia
Published in Blood (06-12-2014)“…Wilms Tumor-1 (WT1) expression level has long been found to be implicated in acute myeloid leukemia (AML) prognosis, though this is not reflected in current…”
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APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts: e0120089
Published in PloS one (01-03-2015)“…Classic deamination mRNA changes, including cytidine to uridine (C-to-U) and adenosine to inosine (A-to-I), are important exceptions to the central dogma and…”
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Development of transgenic mice expressing calcitonin as a beta-lactoglobulin fusion protein in mammary gland
Published in Transgenic research (01-10-2005)“…Expression of foreign proteins in mammalian milk is becoming a widespread strategy for high-level production of recombinant pharmaceuticals, especially those…”
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