Search Results - "Nian, Lim Moon"
-
1
Systematic review and meta-analysis of mesenchymal stromal/stem cells as strategical means for the treatment of COVID-19
Published in Therapeutic Advances in Respiratory Disease (01-01-2023)“…Background: In coronavirus disease 2019 (COVID-19) patients, elevated levels of inflammatory cytokines from over stimulation of immune cells have become a…”
Get full text
Book Review Journal Article -
2
Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour
Published in International journal of molecular sciences (27-07-2018)“…Tapping into the ability of engineered mesenchymal stem cells (MSCs) to mobilise into the tumour has expanded the scope of cancer treatment. Engineered MSCs…”
Get full text
Journal Article -
3
Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer
Published in Cancers (28-08-2019)“…Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target a specific cancer stem cell…”
Get full text
Journal Article -
4
Chemo-Sensitization of CD133+ Cancer Stem Cell Enhances the Effect of Mesenchymal Stem Cell Expressing TRAIL in Non-Small Cell Lung Cancer Cell Lines
Published in Biology (Basel, Switzerland) (26-10-2021)“…Pre-clinical studies have demonstrated the efficacy of mesenchymal stem cells (MSCs) expressing tumor necrosis factor (TNF)-related apoptosis-inducing ligand…”
Get full text
Journal Article -
5
The Effects of Lentivirus-Mediated Gene Silencing of RARβ on the Stemness Capability of Non-Small Cell Lung Cancer
Published in Journal of Cancer (01-01-2021)“…Retinoic acid receptor beta is a nuclear receptor protein that binds to retinoic acid (RA) to mediate cellular signalling in embryogenic morphogenesis, cell…”
Get full text
Journal Article -
6
Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton's jelly mesenchymal stromal cells
Published in Stem cell research & therapy (13-06-2017)“…Mesenchymal stromal cells (MSCs) from various tissues have shown moderate therapeutic efficacy in reversing liver fibrosis in preclinical models. Here, we…”
Get full text
Journal Article -
7
CRISPR/Cas9 in Stem Cell Research: Current Application and Future Perspective
Published in Current stem cell research & therapy (01-01-2018)“…The clustered regularly interspaced short palindromic repeats-associated protein 9 or CRISPR/Cas9 system is one of the hottest topics discussed lately due to…”
Get more information
Journal Article -
8
Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines
Published in Oncology reports (01-01-2016)“…Natural compounds such as curcumin have the ability to enhance the therapeutic effectiveness of common chemotherapy agents through cancer stem-like cell (CSC)…”
Get full text
Journal Article -
9
Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study
Published in Bosnian journal of basic medical sciences (10-11-2016)“…Multiple myeloma (MM) is a malignancy of B lymphocytes or plasma cells. Our array-based comparative genomic hybridization findings revealed chromosomal gains…”
Get full text
Journal Article -
10
Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells
Published in BMC cancer (25-02-2015)“…Despite significant advances in staging and therapies, lung cancer remains a major cause of cancer-related lethality due to its high incidence and recurrence…”
Get full text
Journal Article -
11
Novel triple‑positive markers identified in human non‑small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics
Published in Oncology reports (01-08-2018)“…Through the specific identification and direct targeting of cancer stem cells (CSCs), it is believed that a better treatment efficacy of cancer may be…”
Get full text
Journal Article -
12
Nucleofection optimization and in vitro anti-tumourigenic effect of TRAIL-expressing human adipose-derived mesenchymal stromal cells
Published in Cancer cell international (26-11-2014)“…Tumour homing capacity of engineered human adipose-derived mesenchymal stromal cells (ADMSCs) expressing anti-tumour agents might be the key for a much safer…”
Get full text
Journal Article -
13
Ex vivo expanded SSEA-4+ human limbal stromal cells are multipotent and do not express other embryonic stem cell markers
Published in Molecular vision (14-05-2012)“…The presence of multipotent human limbal stromal cells resembling mesenchymal stromal cells (MSC) provides new insights to the characteristic of these cells…”
Get full text
Journal Article -
14
Modulating multidrug resistance gene in leukaemia cells by short interfering RNA
Published in Singapore medical journal (01-10-2007)“…The multidrug resistance gene, MDR1, is one of the genes responsible for resistance to chemotherapy in the treatment of leukaemia and other cancers. The…”
Get more information
Journal Article -
15
Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase induce growth inhibition and apoptosis in human multiple myeloma cells: a preliminary study
Published in Bosnian journal of basic medical sciences (01-11-2016)“…Multiple myeloma (MM) is a malignancy of B lymphocytes or plasma cells. Our array-based comparative genomic hybridization findings revealed chromosomal gains…”
Get full text
Journal Article