Search Results - "Ni Cheallaigh, Cliona"

GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality by McCrory, Cathal, Fiorito, Giovanni, Hernandez, Belinda, Polidoro, Silvia, O’Halloran, Aisling M, Hever, Ann, Ni Cheallaigh, Cliona, Lu, Ake T, Horvath, Steve, Vineis, Paolo, Kenny, Rose Anne

“…Abstract The aging process is characterized by the presence of high interindividual variation between individuals of the same chronical age prompting a search…”
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Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection by Townsend, Liam, Dyer, Adam H, Jones, Karen, Dunne, Jean, Mooney, Aoife, Gaffney, Fiona, O'Connor, Laura, Leavy, Deirdre, O'Brien, Kate, Dowds, Joanne, Sugrue, Jamie A, Hopkins, David, Martin-Loeches, Ignacio, Ni Cheallaigh, Cliona, Nadarajan, Parthiban, McLaughlin, Anne Marie, Bourke, Nollaig M, Bergin, Colm, O'Farrelly, Cliona, Bannan, Ciaran, Conlon, Niall

“…Fatigue is a common symptom in those presenting with symptomatic COVID-19 infection. However, it is unknown if COVID-19 results in persistent fatigue in those…”
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COVID19 coagulopathy in Caucasian patients by Fogarty, Helen, Townsend, Liam, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Browne, Paul, Bacon, Christopher L., Gaule, Richard, Gillett, Alexander, Byrne, Mary, Ryan, Kevin, O’Connell, Niamh, O’Sullivan, Jamie M., Conlon, Niall, O'Donnell, James S.

“…Summary Although the pathophysiology underlying severe COVID19 remains poorly understood, accumulating data suggest that a lung‐centric coagulopathy may play…”
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Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID‐19): evidence of acute and sustained endothelial cell activation by Ward, Soracha E., Curley, Gerard F., Lavin, Michelle, Fogarty, Helen, Karampini, Ellie, McEvoy, Natalie L., Clarke, Jennifer, Boylan, Maria, Alalqam, Razi, Worrall, Amy P., Kelly, Claire, Barra, Eoghan, Glavey, Siobhan, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Townsend, Liam, Mallon, Patrick W., O'Sullivan, Jamie M., O'Donnell, James S., O'Connell, Niamh, Ryan, Kevin, Byrne, Mary, Preston, Roger, Kenny, Dermot

“…Summary Endothelial cell (EC) activation plays a key role in the pathogenesis of pulmonary microvascular occlusion, which is a hallmark of severe coronavirus…”
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Clarifying the mechanisms and resources that enable the reciprocal involvement of seldom heard groups in health and social care research: A collaborative rapid realist review process by Ní Shé, Éidín, Morton, Sarah, Lambert, Veronica, Ní Cheallaigh, Cliona, Lacey, Vanessa, Dunn, Eleanor, Loughnane, Cliona, O'Connor, Joan, McCann, Amanda, Adshead, Maura, Kroll, Thilo

“…Objective Public and patient involvement is increasingly embedded as a core activity in research funding calls and best practice guidelines. However, there is…”
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Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity by Smith, Nikaïa, Possémé, Céline, Bondet, Vincent, Sugrue, Jamie, Townsend, Liam, Charbit, Bruno, Rouilly, Vincent, Saint-André, Violaine, Dott, Tom, Pozo, Andre Rodriguez, Yatim, Nader, Schwartz, Olivier, Cervantes-Gonzalez, Minerva, Ghosn, Jade, Bastard, Paul, Casanova, Jean Laurent, Szwebel, Tali-Anne, Terrier, Benjamin, Conlon, Niall, O’Farrelly, Cliona, Cheallaigh, Clíona Ní, Bourke, Nollaig M., Duffy, Darragh

“…Host immunity to infection with SARS-CoV-2 is highly variable, dictating diverse clinical outcomes ranging from asymptomatic to severe disease and death. We…”
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Kinetics of the Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response and Serological Estimation of Time Since Infection by Pelleau, Stéphane, Woudenberg, Tom, Rosado, Jason, Donnadieu, Françoise, Garcia, Laura, Obadia, Thomas, Gardais, Soazic, Elgharbawy, Yasmine, Velay, Aurelie, Gonzalez, Maria, Nizou, Jacques Yves, Khelil, Nizar, Zannis, Konstantinos, Cockram, Charlotte, Merkling, Sarah Hélène, Meola, Annalisa, Kerneis, Solen, Terrier, Benjamin, de Seze, Jerome, Planas, Delphine, Schwartz, Olivier, Dejardin, François, Petres, Stéphane, von Platen, Cassandre, Pellerin, Sandrine Fernandes, Arowas, Laurence, de Facci, Louise Perrin, Duffy, Darragh, Cheallaigh, Clíona Ní, Dunne, Jean, Conlon, Niall, Townsend, Liam, Duong, Veasna, Auerswald, Heidi, Pinaud, Laurie, Tondeur, Laura, Backovic, Marija, Hoen, Bruno, Fontanet, Arnaud, Mueller, Ivo, Fafi-Kremer, Samira, Bruel, Timothée, White, Michael

“…Abstract Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a complex antibody response that varies by orders of…”
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Investigating the Relationship between Vitamin D and Persistent Symptoms Following SARS-CoV-2 Infection by Townsend, Liam, Dyer, Adam H, McCluskey, Patrick, O'Brien, Kate, Dowds, Joanne, Laird, Eamon, Bannan, Ciaran, Bourke, Nollaig M, Ní Cheallaigh, Cliona, Byrne, Declan G, Kenny, Rose Anne

“…The emergence of persistent symptoms following SARS-CoV-2 infection, known as , is providing a new challenge to healthcare systems. The cardinal features are…”
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A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling by Ní Cheallaigh, Clíona, Sheedy, Frederick J., Harris, James, Muñoz-Wolf, Natalia, Lee, Jinhee, West, Kim, McDermott, Eva Palsson, Smyth, Alicia, Gleeson, Laura E., Coleman, Michelle, Martinez, Nuria, Hearnden, Claire H.A., Tynan, Graham A., Carroll, Elizabeth C., Jones, Sarah A., Corr, Sinéad C., Bernard, Nicholas J., Hughes, Mark M., Corcoran, Sarah E., O’Sullivan, Mary, Fallon, Ciara M., Kornfeld, Hardy, Golenbock, Douglas, Gordon, Stephen V., O’Neill, Luke A.J., Lavelle, Ed C., Keane, Joseph

“…Humans that are heterozygous for the common S180L polymorphism in the Toll-like receptor (TLR) adaptor Mal (encoded by TIRAP) are protected from a number of…”
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Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity by Phelan, Thomas, Dunne, Jean, Conlon, Niall, Cheallaigh, Clíona Ní, Abbott, W. Mark, Faba-Rodriguez, Raquel, Amanat, Fatima, Krammer, Florian, Little, Mark A., Hughes, Gerry, Bergin, Colm, Kerr, Colm, Sundaresan, Sudharshana, Long, Aideen, McCormack, William, Brady, Gareth

“…Serological assays have been widely employed during the coronavirus disease 2019 (COVID-19) pandemic to measure antibody responses to severe acute respiratory…”
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High-Cost, High-Need Users of Acute Unscheduled HIV Care: A Cross-Sectional Study by Grant, Conor, Bergin, Colm, O'Connell, Sarah, Cotter, John, Ní Cheallaigh, Clíona

“…High-cost, high-need users are defined as patients who accumulate large numbers of emergency department visits and hospital admissions that might have been…”
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Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression by Townsend, Liam, Dyer, Adam H., Naughton, Aifric, Imangaliyev, Sultan, Dunne, Jean, Kiersey, Rachel, Holden, Dean, Mooney, Aoife, Leavy, Deirdre, Ridge, Katie, Sugrue, Jamie, Aldoseri, Mubarak, Kelliher, Jo Hannah, Hennessy, Martina, Byrne, Declan, Browne, Paul, Bacon, Christopher L., Doyle, Catriona, O’Riordan, Ruth, McLaughlin, Anne-Marie, Bannan, Ciaran, Martin-Loeches, Ignacio, White, Arthur, McLoughlin, Rachel M., Bergin, Colm, Bourke, Nollaig M., O’Farrelly, Cliona, Conlon, Niall, Cheallaigh, Clíona Ní

“…SARS-CoV-2 infection causes a wide spectrum of disease severity. Identifying the immunological characteristics of severe disease and the risk factors for their…”
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Prolonged elevation of D‐dimer levels in convalescent COVID‐19 patients is independent of the acute phase response by Townsend, Liam, Fogarty, Helen, Dyer, Adam, Martin‐Loeches, Ignacio, Bannan, Ciaran, Nadarajan, Parthiban, Bergin, Colm, O’Farrelly, Cliona, Conlon, Niall, Bourke, Nollaig M., Ward, Soracha E., Byrne, Mary, Ryan, Kevin, O’Connell, Niamh, O’Sullivan, Jamie M., Ni Cheallaigh, Cliona, O’Donnell, James S.

“…Background Persistent fatigue, breathlessness, and reduced exercise tolerance have been reported following acute COVID‐19 infection. Although immuno‐thrombosis…”
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Persistent endotheliopathy in the pathogenesis of long COVID syndrome by Fogarty, Helen, Townsend, Liam, Morrin, Hannah, Ahmad, Azaz, Comerford, Claire, Karampini, Ellie, Englert, Hanna, Byrne, Mary, Bergin, Colm, O’Sullivan, Jamie M., Martin‐Loeches, Ignacio, Nadarajan, Parthiban, Bannan, Ciaran, Mallon, Patrick W., Curley, Gerard F., Preston, Roger J. S., Rehill, Aisling M., McGonagle, Dennis, Ni Cheallaigh, Cliona, Baker, Ross I., Renné, Thomas, Ward, Soracha E., O’Donnell, James S., O’Connell, Niamh, Ryan, Kevin, Kenny, Dermot, Fazavana, Judicael

“…Background Persistent symptoms including breathlessness, fatigue, and decreased exercise tolerance have been reported in patients after acute SARS‐CoV‐2…”
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Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity by Townsend, Liam, Dowds, Joanne, O'Brien, Kate, Sheill, Grainne, Dyer, Adam H, O'Kelly, Brendan, Hynes, John P, Mooney, Aoife, Dunne, Jean, Ni Cheallaigh, Cliona, O'Farrelly, Cliona, Bourke, Nollaig M, Conlon, Niall, Martin-Loeches, Ignacio, Bergin, Colm, Nadarajan, Parthiban, Bannan, Ciaran

“…Much is known about the acute infective process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of the coronavirus disease…”
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More on COVID‐19 coagulopathy in Caucasian patients by Fogarty, Helen, Townsend, Liam, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Browne, Paul, Bacon, Christopher L., Gaule, Richard, Gillett, Alexander, Byrne, Mary, Ryan, Kevin, O'Connell, Niamh, O'Sullivan, Jamie M., Conlon, Niall, O'Donnell, James S.

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How does socio-economic position (SEP) get biologically embedded? A comparison of allostatic load and the epigenetic clock(s) by McCrory, Cathal, Fiorito, Giovanni, Ni Cheallaigh, Cliona, Polidoro, Silvia, Karisola, Piia, Alenius, Harri, Layte, Richard, Seeman, Teresa, Vineis, Paolo, Kenny, Rose Anne

“…•Low socio-economic position (SEP) is linked with earlier morbidity and mortality.•Researchers have debated how the social environment gets biologically…”
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Feasibility of a Broad Test Battery to Assess Physical Functioning Limitations of People Experiencing Homelessness by Broderick, Julie, Kiernan, Sinead, Murphy, Niamh, Dowds, Joanne, Ní Cheallaigh, Cliona

“…People who are homeless experience poor health. Reflective of overall health and factors such as acquired injuries, physical ability or functioning is often…”
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ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19 by Ward, Soracha E., Fogarty, Helen, Karampini, Ellie, Lavin, Michelle, Schneppenheim, Sonja, Dittmer, Rita, Morrin, Hannah, Glavey, Siobhan, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Mallon, Patrick W., Curley, Gerard F., Baker, Ross I., Budde, Ulrich, O’Sullivan, Jamie M., O’Donnell, James S., O’Connell, Niamh, Byrne, Mary, Townsend, Liam, McEvoy, Natalie L., Clarke, Jennifer, Boylan, Maria, Alalqam, Razi, Worrall, Amy P., Kelly, Claire, de Barra, Eoghan, Preston, Roger, Kenny, Dermot

“…Background Consistent with fulminant endothelial cell activation, elevated plasma von Willebrand factor (VWF) antigen levels have been reported in patients…”
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Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction by Fogarty, Helen, Ward, Soracha E., Townsend, Liam, Karampini, Ellie, Elliott, Stephanie, Conlon, Niall, Dunne, Jean, Kiersey, Rachel, Naughton, Aifric, Gardiner, Mary, Byrne, Mary, Bergin, Colm, O'Sullivan, Jamie M., Martin-Loeches, Ignacio, Nadarajan, Parthiban, Bannan, Ciaran, Mallon, Patrick W., Curley, Gerard F., Preston, Roger J.S., Rehill, Aisling M., Baker, Ross I., Cheallaigh, Cliona Ni, O'Donnell, James S., O’Connell, Niamh, Ryan, Kevin, Kenny, Dermot, Fazavana, Judicael

“…Prolonged recovery is common after acute SARS-CoV-2 infection; however, the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown…”
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