Search Results - "Ni, Yanghong"
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Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance
Published in Frontiers in immunology (15-09-2022)“…Immune checkpoint blockade (ICB) has rapidly transformed the treatment paradigm for various cancer types. Multiple single or combinations of ICB treatments…”
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Molecular mechanisms of ROS-modulated cancer chemoresistance and therapeutic strategies
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive oxygen species (ROS) are master regulators of cancer development…”
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The Role of Tumor-Stroma Interactions in Drug Resistance Within Tumor Microenvironment
Published in Frontiers in cell and developmental biology (20-05-2021)“…Cancer cells resistance to various therapies remains to be a key challenge nowadays. For a long time, scientists focused on tumor cells themselves for the…”
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Metabolic reprogramming of the tumor immune microenvironment in ovarian cancer: A novel orientation for immunotherapy
Published in Frontiers in immunology (14-10-2022)“…Ovarian cancer is the most lethal gynecologic tumor, with the highest mortality rate. Numerous studies have been conducted on the treatment of ovarian cancer…”
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Ginkgo biloba derivative ginkgetin inhibits breast cancer growth by regulating the miRNA-122-5p/GALNT10 axis
Published in Chinese medical journal (05-10-2024)“…[...]the anti-tumor effect of Gk and the involvement of the miR-122-5p/polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10) axis were assessed in an…”
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Myeloid-Derived Suppressor Cells: Implications in the Resistance of Malignant Tumors to T Cell-Based Immunotherapy
Published in Frontiers in cell and developmental biology (14-07-2021)“…T lymphocytes function as major players in antigen-mediated cytotoxicity and have become powerful tools for exploiting the immune system in tumor elimination…”
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Immunological perspectives on the pathogenesis, diagnosis, prevention and treatment of COVID-19
Published in Molecular biomedicine (20-01-2021)“…Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 can spread…”
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Metabolic cross-talk between ovarian cancer and the tumor microenvironment-providing potential targets for cancer therapy
Published in Frontiers in bioscience (Landmark. Print) (20-04-2022)“…Conventional treatments for ovarian cancer, including debulking cytoreductive surgery combined with carboplatin/paclitaxel-based chemotherapy, are…”
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Heterologous vaccination with subunit protein vaccine induces a superior neutralizing capacity against BA.4/5‐included SARS‐CoV‐2 variants than homologous vaccination of mRNA vaccine
Published in MedComm (2020) (01-04-2023)“…BA.4 and BA.5 (BA.4/5), the subvariants of Omicron, are more transmissible than BA.1 with more robust immune evasion capability because of its unique spike…”
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Immunological perspectives on the pathogenesis, diagnosis, prevention and treatment of COVID-19
Published in Molecular biomedicine (20-01-2021)“…Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 can spread…”
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