Search Results - "Ni, Kainan"

Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 Signaling by Pan, Bin, Zheng, Lin, Fang, Jiawei, Lin, Ye, Lai, Hehuan, Gao, Jiawei, Pan, Wenzheng, Zhang, Yejin, Ni, Kainan, Lou, Chao, He, Dengwei

“…Osteoporosis is characterized by a decrease in bone mass and destruction of the bone microarchitecture, and it commonly occurs in postmenopausal women and the…”
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Multifunctional nanomaterials via cell cuproptosis and oxidative stress for treating osteosarcoma and OS-induced bone destruction by Ye, Lin, Yu, Congcong, Xia, Jiechao, Ni, Kainan, Zhang, Yejin, Ying, Xiaozhang, Xie, Dingqi, Jin, Yang, Sun, Rongtai, Tang, Ruikang, Fan, Shunwu, Yao, Shasha

“…Reactive Oxygen Species (ROS) refers to a highly reactive class of oxidizing species that have the potential to induce cellular apoptosis and necrosis…”
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Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration by Lai, Hehuan, Fan, Jialin, Zhang, Yejin, Pan, Bin, Pan, Wenzheng, Fang, Jiawei, Ni, Kainan, Chen, Zhenzhong, Liu, Shijie, Lou, Chao, He, Dengwei

“…Recently, studies on microRNAs (miRNAs) and their targets and related genes have provided new therapeutic opportunities for controlling intervertebral disc…”
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MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1 by Pan, Bin, Zheng, Lin, Liu, Shijie, Fang, Jiawei, Lou, Chao, Hu, Xingyu, Ye, Lin, Lai, Hehuan, Gao, Jiawei, Zhang, Yejin, Ni, Kainan, He, Dengwei

“…Bone metabolic homeostasis is largely dependent on the dynamic balance between osteoblasts and osteoclasts. MicroRNAs (miRNAs) play critical roles in…”
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Macrophage migration inhibitory factor (MIF) promotes intervertebral disc degeneration through the NF‐κB pathway, and the MIF inhibitor CPSI‐1306 alleviates intervertebral disc degeneration in a mouse model by Zhang, Yejin, Zheng, Lin, Fang, Jiawei, Ni, Kainan, Hu, Xingyu, Ye, Lin, Lai, Hehuan, Yang, Tao, Chen, Zhenzhong, He, Dengwei

“…Lumbar intervertebral disc degeneration(IDD) is a prevalent inflammatory disease caused by many proinflammatory factors, such as TNF and IL‐1β. Migration…”
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Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway by Yang, Tao, Ma, Haiwei, Lai, Hehuan, Lu, Yahong, Ni, Kainan, Hu, Xingyu, Zhou, Yang, Zhou, Zhiguo, Li, Weiqing, Fang, Jiawei, Zhang, Yejin, Chen, Zhenzhong, He, Dengwei

“…Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage degeneration and subchondral bone remodelling. Currently, conservative…”
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Carnitine functions as an enhancer of NRF2 to inhibit osteoclastogenesis via regulating macrophage polarization in osteoporosis by Yang, Tao, Liu, Shijie, Ma, Haiwei, Lai, Hehuan, Wang, Chengdi, Ni, Kainan, Lu, Yahong, Li, Weiqing, Hu, Xingyu, Zhou, Zhiguo, Lou, Chao, He, Dengwei

“…Osteoporosis, which manifests as reduced bone mass and deteriorated bone quality, is common in the elderly population. It is characterized by persistent…”
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