Search Results - "Ni, Hui‐Qi"

Catalytic Carbo- and Aminoboration of Alkenyl Carbonyl Compounds via Five- and Six-Membered Palladacycles by Liu, Zhen, Ni, Hui-Qi, Zeng, Tian, Engle, Keary M

“…A palladium­(II)-catalyzed alkene difunctionalization reaction has been developed, wherein B2pin2 is used to trap chelation-stabilized alkylpalladium­(II)…”
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Nickel‐Catalyzed Reductive Cross‐Coupling of Aryl Halides with Monofluoroalkyl Halides for Late‐Stage Monofluoroalkylation by Sheng, Jie, Ni, Hui‐Qi, Zhang, Hao‐Ran, Zhang, Kai‐Fan, Wang, Yi‐Ning, Wang, Xi‐Sheng

“…A combinatorial nickel‐catalyzed monofluoroalkylation of aryl halides with unactivated fluoroalkyl halides by reductive cross‐coupling has been developed. This…”
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Diversity‐Oriented Synthesis of Aliphatic Fluorides via Reductive C(sp3)−C(sp3) Cross‐Coupling Fluoroalkylation by Sheng, Jie, Ni, Hui‐Qi, Ni, Shan‐Xiu, He, Yan, Cui, Ru, Liao, Guang‐Xu, Bian, Kang‐Jie, Wu, Bing‐Bing, Wang, Xi‐Sheng

“…Monofluorinated alkyl compounds are of great importance in pharmaceuticals, agrochemicals and materials. Herein, we describe a direct nickel‐catalyzed…”
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Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation by Ni, Hui-Qi, Kevlishvili, Ilia, Bedekar, Pranali G., Barber, Joyann S., Yang, Shouliang, Tran-Dubé, Michelle, Romine, Andrew M., Lu, Hou-Xiang, McAlpine, Indrawan J., Liu, Peng, Engle, Keary M.

“…2,3-Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, we describe a method that enables direct access to…”
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Catalytic σ‐Bond Annulation with Ambiphilic Organohalides Enabled by β‐X Elimination by Ni, Hui‐Qi, Dai, Jing‐Cheng, Yang, Shouliang, Loach, Richard P., Chuba, Matthew D., McAlpine, Indrawan J., Engle, Keary M.

“…We describe a catalytic cascade sequence involving directed C(sp3)−H activation followed by β‐heteroatom elimination to generate a PdII(π‐alkene) intermediate…”
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Nickel‐Catalyzed Direct Trifluoroethylation of Aryl Iodides with 1,1,1‐Trifluoro‐2‐Iodoethane via Reductive Coupling by Li, Han, Sheng, Jie, Liao, Guang‐Xu, Wu, Bing‐Bing, Ni, Hui‐Qi, Li, Yan, Wang, Xi‐Sheng

“…A nickel‐catalyzed direct trifluoroethylation of aryl iodides with an industrial raw material CF3CH2I has been developed, demonstrating high efficiency,…”
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PdII‐Catalyzed C(alkenyl)−H Activation Facilitated by a Transient Directing Group by Liu, Mingyu, Sun, Juntao, Erbay, Tuğçe G., Ni, Hui‐Qi, Martín‐Montero, Raúl, Liu, Peng, Engle, Keary M.

“…Palladium(II)‐catalyzed C(alkenyl)−H alkenylation enabled by a transient directing group (TDG) strategy is described. The dual catalytic process takes…”
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Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis by Ni, Hui‐Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran‐Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.

“…In this study, we systematically evaluate different ambiphilic organohalides for their ability to participate in anti‐selective carbo‐ or heteroannulation with…”
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Controlling cyclization pathways in palladium(ii)-catalyzed intramolecular alkene hydro-functionalization via substrate directivity by Wang, Xin, Li, Zi-Qi, Mai, Binh Khanh, Gurak, Jr, John A, Xu, Jessica E, Tran, Van T, Ni, Hui-Qi, Liu, Zhen, Liu, Zhonglin, Yang, Kin S, Xiang, Rong, Liu, Peng, Engle, Keary M

“…We report a series of palladium(ii)-catalyzed, intramolecular alkene hydrofunctionalization reactions with carbon, nitrogen, and oxygen nucleophiles to form…”
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Combinatorial Nickel-Catalyzed Monofluoroalkylation of Aryl Boronic Acids with Unactivated Fluoroalkyl Iodides by Sheng, Jie, Ni, Hui-Qi, Liu, Ge, Li, Yan, Wang, Xi-Sheng

“…A combinatorial nickel-catalyzed cross-coupling between arylboronic acids and unactived 1-fluoro-1-iodoalkanes has been developed, which demonstrated high…”
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Pd II -Catalyzed C(alkenyl)-H Activation Facilitated by a Transient Directing Group by Liu, Mingyu, Sun, Juntao, Erbay, Tuğçe G, Ni, Hui-Qi, Martín-Montero, Raúl, Liu, Peng, Engle, Keary M

“…Palladium(II)-catalyzed C(alkenyl)-H alkenylation enabled by a transient directing group (TDG) strategy is described. The dual catalytic process takes…”
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Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd(II)/Pd(IV) Catalysis by Ni, Hui-Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran-Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.

“…In this study, we systematically evaluate different ambiphilic organohalides for their ability to participate in anti -selective carbo- or heteroannulation…”
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Directed, nickel-catalyzed 1,2-alkylsulfenylation of alkenyl carbonyl compounds by Li, Zi-Qi, He, Wen-Ji, Ni, Hui-Qi, Engle, Keary M

“…We report a regioselective, nickel-catalyzed syn -1,2-carbosulfenylation of non-conjugated alkenyl carbonyl compounds with alkyl/arylzinc nucleophiles and…”
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Redox-Paired Alkene Difunctionalization Enables Skeletally Divergent Synthesis by Ni, Hui-Qi, Karunananda, Malkanthi K., Zeng, Tian, Yang, Shenghua, Liu, Zhen, Houk, K.N., Liu, Peng, Engle, Keary M.

“…Multistep organic synthesis enables conversion of simple chemical feedstocks into a more structurally complex product that serves a particular function. The…”
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Modular synthesis of non-conjugated N-(quinolin-8-yl) alkenyl amides via cross-metathesis by Ni, Hui-Qi, Li, Zi-Qi, Tran, Van T., Engle, Keary M.

“…We report a direct and modular method to access non-conjugated alkenyl amides containing the 8-aminoquinoline (AQ) directing auxiliary and related groups via…”
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Catalytic Addition of Nitroalkanes to Unactivated Alkenes via Directed Carbopalladation by Simlandy, Amit Kumar, Rodphon, Warabhorn, Alturaifi, Turki M., Mai, Binh Khanh, Ni, Hui-Qi, Gurak, John A., Liu, Peng, Engle, Keary M.

“…We report a redox-neutral catalytic coupling of nitroalkanes and unactivated alkenes that proceeds by a directed carbopalladation mechanism. The reaction is…”
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Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd II /Pd IV Catalysis by Ni, Hui-Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G, Donaldson, Joyann S, Tran-Dubé, Michelle, McAlpine, Indrawan J, Engle, Keary M

“…In this study, we systematically evaluate different ambiphilic organohalides for their ability to participate in anti-selective carbo- or heteroannulation with…”
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Nickel-catalyzed hydromonofluoromethylation of unactivated alkenes for expedient construction of primary alkyl fluorides by Ni, Shan-Xiu, Li, Yan-Lin, Ni, Hui-Qi, Bi, Yu-Xiang, Sheng, Jie, Wang, Xi-Sheng

“…A nickel-catalyzed direct hydromonofluoromethylation of unactivated olefins with industrial raw fluoroiodomethane is developed, furnishing various primary…”
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Catalytic σ‐Bond Annulation with Ambiphilic Organohalides Enabled by β‐X Elimination by Ni, Hui‐Qi, Dai, Jing‐Cheng, Yang, Shouliang, Loach, Richard P., Chuba, Matthew D., McAlpine, Indrawan J., Engle, Keary M.

“…We describe a catalytic cascade sequence involving directed C(sp3)−H activation followed by β‐heteroatom elimination to generate a PdII(π‐alkene) intermediate…”
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PdII‐Catalyzed C(alkenyl)−H Activation Facilitated by a Transient Directing Group by Liu, Mingyu, Sun, Juntao, Erbay, Tuğçe G., Ni, Hui‐Qi, Martín‐Montero, Raúl, Liu, Peng, Engle, Keary M.

“…Palladium(II)‐catalyzed C(alkenyl)−H alkenylation enabled by a transient directing group (TDG) strategy is described. The dual catalytic process takes…”
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