Search Results - "Ni, H M"

4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes by Akakpo, J Y, Ramachandran, A, Kandel, S E, Ni, H M, Kumer, S C, Rumack, B H, Jaeschke, H

“…Liver injury due to acetaminophen (APAP) overdose is the major cause of acute liver failure in the United States. While treatment with N-acetylcysteine is the…”
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A new fish scale-derived scaffold for corneal regeneration by Lin, Chien Chen, Ritch, Robert, Lin, Shang Ming, Ni, Mei-Hui, Chang, Yu-Chung, Lu, Yi Lung, Lai, Hong Ji, Lin, Feng-Huei

“…The purpose of this study is to develop a novel scaffold, derived from fish scales, as an alternative functional material with sufficient mechanical strength…”
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Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase). Evidence that auto-kinase belongs to a member of the p21-activated kinase family by Yu, J S, Chen, W J, Ni, M H, Chan, W H, Yang, S D

“…Autophosphorylation-dependent protein kinase (auto-kinase) was identified from pig brain and liver on the basis of its unique autophosphorylation/activation…”
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A new synthesis of carboxyterfenadine (fexofenadine) and its bioisosteric tetrazole analogs by Di Giacomo, Barbara, Coletta, Donato, Natalini, Benedetto, Ni, Ming-Hong, Pellicciari, Roberto

“…A new synthesis of carboxyterfenadine ( 4), based on the conversion of a α-halo-alkylarylketone into the corresponding substituted 2-arylalkanoic ester, is…”
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Synthesis and biological evaluation of 6-carboxy-3,4-methanoprolines, new rigid glutamate analogs by Marinozzi, M, Natalini, B, Ni, M H, Costantino, G, Pellicciari, R, Thomsen, C

“…6-Carboxy-3,4-methanoprolines were prepared by reacting ethyl diazoacetate with the suitable 3,4-didehydroproline derivative in the presence of…”
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p53 Up‐regulated Modulator of Apoptosis Induction Mediates Acetaminophen‐Induced Necrosis and Liver Injury in Mice by Chen, Dongshi, Ni, Hong‐Min, Wang, Lei, Ma, Xiaowen, Yu, Jian, Ding, Wen‐Xing, Zhang, Lin

“…Acetaminophen (APAP) overdose is one of the leading causes of hepatotoxicity and acute liver failure in the United States. Accumulating evidence suggests that…”
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Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice by Wang, Hua, Ni, Hong-Min, Chao, Xiaojuan, Ma, Xiaowen, Rodriguez, Yssa Ann, Chavan, Hemantkumar, Wang, Shaogui, Krishnamurthy, Partha, Dobrowsky, Rick, Xu, De-Xiang, Jaeschke, Hartmut, Ding, Wen-Xing

“…Mitochondria damage plays a critical role in acetaminophen (APAP)-induced necrosis and liver injury. Cells can adapt and protect themselves by removing damaged…”
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Overexpression of protein kinase FA/GSK-3α (a proline-directed protein kinase) correlates with human hepatoma dedifferentiation/progression by Yang, Shiaw-Der, Yu, Jau-Song, Yang, Chuan-Ching, Lee, Shan-Chih, Lee, Tsong-Tze, Ni, Mei-Hui, Kuan, Chu-Yun, Chen, Hsiang-Chin

“…Computer analysis of protein phosphorylation sites sequence revealed that transcriptional factors and viral oncoproteins are prime targets for regulation of…”
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Dysfunction of protein kinase FA/GSK-3 alpha in lymphocytes of patients with schizophrenic disorder by Yang, S D, Yu, J S, Lee, T T, Yang, C C, Ni, M H, Yang, Y Y

“…As compared to normal people, the lymphocytes of patients with schizophrenia were found to have an impairment of ATP.Mg-dependent protein phosphatase…”
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Chlorpromazine protects against acetaminophen-induced liver injury in mice by modulating autophagy and c-Jun N-terminal kinase activation by Li, Yuan, Ni, Hong-Min, Jaeschke, Hartmut, Ding, Wen-Xing

“…Overdose of acetaminophen (APAP) leads to liver injury, which is one of the most common causes of liver failure in the United States. We previously…”
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Bid‐dependent generation of oxygen radicals promotes death receptor activation–induced apoptosis in murine hepatocytes by Ding, Wen‐Xing, Ni, Hong‐Min, DiFrancesca, Daniell, Stolz, Donna B., Yin, Xiao‐Ming

“…Activation of tumor necrosis factor receptor 1 or Fas leads to the generation of reactive oxygen species, which are important to the cytotoxic effects of tumor…”
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Direct simulation of falling droplet in a closed channel by Ni, Ming-Jiu, Komori, Satoru, Morley, Neil B.

“…The direct simulation of a droplet falling in a different background liquid is presented. The complete Navier–Stokes problem is solved using a projection…”
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Deletion of Bid Impedes Cell Proliferation and Hepatic Carcinogenesis by Bai, Li, Ni, Hong-Min, Chen, Xiaoyun, DiFrancesca, Daniell, Yin, Xiao-Ming

“…Mechanisms that control the proliferation capability of the initiated cells during hepatocarcinogenesis are still largely unclear. We investigated the role of…”
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Mechanism of Soap-Free Emulsion Polymerization of Styrene and 4-Vinylpyridine:  Characteristics of Reaction in the Monomer Phase, Aqueous Phase, and Their Interface by Ni, Henmei, Du, Yongzhong, Ma, Guanghui, Nagai, Masatoshi, Omi, Shinzo

“…The characteristics of reactions in the monomer phase, aqueous phase, and the interface of monomer/aqueous phase of soap-free emulsion polymerization of…”
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Proteolytic cleavage and activation of PAK2 during UV irradiation-induced apoptosis in A431 cells by Tang, Tswen-Kei, Chang, Wen-Chang, Chan, Wen-Hsiung, Yang, Shiaw-Der, Ni, Mei-Hui, Yu, Jau-Song

“…Exposure of mammalian cells to ultraviolet (UV) light elicits a cellular response and can also lead to apoptotic cell death. In this report, we show that a…”
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Partial likelihood for online order selection by Adalı, Tülay, Ni, Hongmei

“…Partial likelihood (PL) is a flexible framework for adaptive nonlinear signal processing allowing the use of a wide class of nonlinear structures—probability…”
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Incorporation of the Unusual Cα-Fluoroalkylamino Acids into Cyclopeptides:  Synthesis of Arginine−Glycine−Aspartate (RGD) Analogues and Study of Their Conformational and Biological Behavior by Dal Pozzo, Alma, Ni, Minghong, Muzi, Laura, de Castiglione, Roberto, Mondelli, Rosanna, Mazzini, Stefania, Penco, Sergio, Pisano, Claudio, Castorina, Massimo, Giannini, Giuseppe

“…A series of six arginine−glycine−aspartate (RGD) cyclopeptide analogues containing a Cα-di- or trifluoromethylamino acid (α-Dfm or α-TfmAaa) at different…”
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Amino acid bromides: their utilization for difficult couplings in solid-phase peptide synthesis by Ni, Minghong, Esposito, Emiliano, Kaptein, Bernard, Broxterman, Quirinus B., Dal Pozzo, Alma

“…Use of N-protected-α-amino acid bromides for facile solid-phase synthesis of peptides (SPPS) containing extremely sterically hindered non-proteinogenic amino…”
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Partial likelihood for signal processing by Adali, T., Hongmei Ni

“…We present partial likelihood (PL) as an effective means for developing nonlinear techniques for signal processing. Posing signal processing problems in a…”
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N-Protected amino acid bromides: efficient reagents for the incorporation into peptides of extremely hindered α,α-dialkyl- and α-fluoroalkyl-amino acids by DalPozzo, Alma, Bergonzi, Roberto, Ni, Minghong

“…N-Protected amino acid bromides were found to be exceptionally well suited for the coupling of extremely hindered amino acids. Bromides were generated in situ…”
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