Search Results - "Ngwenya, Laura B"
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Impact of Traumatic Brain Injury on Neurogenesis
Published in Frontiers in neuroscience (09-01-2019)“…New neurons are generated in the hippocampal dentate gyrus from early development through adulthood. Progenitor cells and immature granule cells in the…”
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Pioglitazone improves working memory performance when administered in chronic TBI
Published in Neurobiology of disease (01-12-2019)“…Traumatic brain injury (TBI) is a leading cause of long-term disability in the United States. Even in comparatively mild injuries, cognitive and behavioral…”
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Lack of Glutamate Receptor Subunit Expression Changes in Hippocampal Dentate Gyrus after Experimental Traumatic Brain Injury in a Rodent Model of Depression
Published in International journal of molecular sciences (01-08-2021)“…Traumatic brain injury (TBI) affects over 69 million people annually worldwide, and those with pre-existing depression have worse recovery. The molecular…”
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Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion?
Published in Frontiers in systems neuroscience (16-05-2018)Get full text
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Clinical Impact of Standardized Interpretation and Reporting of Multimodality Neuromonitoring Data
Published in Critical care explorations (01-08-2024)“…Evaluate the consistency and clinical impact of standardized multimodality neuromonitoring (MNM) interpretation and reporting within a system of care for…”
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Concomitant epidural and subdural spinal abscess: a case report
Published in The spine journal (01-04-2016)“…Abstract Background Context Spinal subdural abscess (SSA) is a rare occurrence for which the management typically involves open surgical removal and washout…”
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Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury
Published in IBRO neuroscience reports (01-06-2021)“…It has been demonstrated that adult born granule cells are generated after traumatic brain injury (TBI). There is evidence that these newly generated neurons…”
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Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence
Published in Brain sciences (25-07-2017)“…The prevalence of neuropsychiatric disorders following traumatic brain injury (TBI) is 20%-50%, and disorders of mood and cognition may remain even after…”
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Commentary: Concussion Guidelines Step 2: Evidence for Subtype Classification
Published in Neurosurgery (01-01-2020)Get full text
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Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice
Published in Stem cells international (01-01-2018)“…Cognitive deficits after traumatic brain injury (TBI) are debilitating and contribute to the morbidity and loss of productivity of over 10 million people…”
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Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies
Published in Molecular psychiatry (01-07-2019)“…Traumatic brain injury (TBI) is a pervasive problem in the United States and worldwide, as the number of diagnosed individuals is increasing yearly and there…”
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Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey
Published in Journal of comparative neurology (1911) (10-09-2006)“…The generation of new neurons in the hippocampal dentate gyrus of adult mammals has been characterized in rodents, but the details of this process have not…”
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Sacral Rheumatoid Nodule: An Unusual Indication for Coccygectomy
Published in Case reports in surgery (2020)“…Here, we present a case report of a woman who presented with a large sacral rheumatoid nodule. This patient failed conservative treatment and presented in…”
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Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury
Published in JAMA neurology (01-04-2020)“…Advances in treatment of traumatic brain injury are hindered by the inability to monitor pathological mechanisms in individual patients for targeted…”
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Sustainability of Applied Intracranial Multimodality Neuromonitoring After Severe Brain Injury
Published in World neurosurgery (01-04-2019)Get full text
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An ultrastructural characterization of the newly generated cells in the adult monkey dentate gyrus
Published in Hippocampus (01-01-2008)“…Recent studies of adult neurogenesis in the hippocampus have focused on the maturational sequence and on the identification of the neural stem cell in the…”
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Improving Neurotrauma by Depolarization Inhibition With Combination Therapy: A Phase 2 Randomized Feasibility Trial
Published in Neurosurgery (01-10-2023)“…Spreading depolarizations (SDs) are a pathological mechanism that mediates lesion development in cerebral gray matter. They occur in ∼60% of patients with…”
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Gender disparities in academic rank achievement in neurosurgery: a critical assessment
Published in Journal of neurosurgery (01-12-2020)“…The objective of this study was to evaluate whether there are disparities in academic rank and promotion between men and women neurosurgeons. The profiles of…”
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Autonomic dysfunction following traumatic brain injury: translational insights
Published in Neurosurgical focus (01-11-2019)“…Although there is a substantial amount of research on the neurological consequences of traumatic brain injury (TBI), there is a knowledge gap regarding the…”
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Diffusion-Weighted Imaging Reveals Distinct Patterns of Cytotoxic Edema in Patients with Subdural Hematomas
Published in Journal of neurotrauma (01-10-2021)“…Subdural hematomas (SDHs) are increasingly common and can cause ischemic brain injury. Previous work has suggested that this is driven largely by vascular…”
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