Search Results - "Nguyen, Van T. M."

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression by Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E., Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M., Nguyen, Van T. M., Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Niccola, Gress, Thomas M., Jiao, Long R., Lombardo, Ylenia, Lemoine, Nicholas R., Heeschen, Christopher, Castellano, Leandro

“…TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated…”
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Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion by Nguyen, Van T. M., Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Meira, Alba, Patten, Darren K., Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R. Charles, Magnani, Luca

“…Endocrine therapies target the activation of the oestrogen receptor alpha (ERα) via distinct mechanisms, but it is not clear whether breast cancer cells can…”
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Author Correction: TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression by Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E., Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M., Nguyen, Van T. M., Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Niccola, Gress, Thomas M., Jiao, Long R., Lombardo, Ylenia, Lemoine, Nicholas R., Heeschen, Christopher, Castellano, Leandro

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion by Nguyen, Van T. M., Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Rodriguez-Meira, Alba, Patten, Darren K., Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R. Charles, Magnani, Luca

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution by Schade, Amy E, Perurena, Naiara, Yang, Yoona, Rodriguez, Carrie L, Krishnan, Anjana, Gardner, Alycia, Loi, Patrick, Xu, Yilin, Nguyen, Van T M, Mastellone, G M, Pilla, Natalie F, Watanabe, Marina, Ota, Keiichi, Davis, Rachel A, Mattioli, Kaia, Xiang, Dongxi, Zoeller, Jason J, Lin, Jia-Ren, Morganti, Stefania, Garrido-Castro, Ana C, Tolaney, Sara M, Li, Zhe, Barbie, David A, Sorger, Peter K, Helin, Kristian, Santagata, Sandro, Knott, Simon R V, Cichowski, Karen

“…Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and has the highest rate of recurrence . The predominant standard of care for…”
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APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer by Periyasamy, Manikandan, Patel, Hetal, Lai, Chun-Fui, Nguyen, Van T.M., Nevedomskaya, Ekaterina, Harrod, Alison, Russell, Roslin, Remenyi, Judit, Ochocka, Anna Maria, Thomas, Ross S., Fuller-Pace, Frances, Győrffy, Balázs, Caldas, Carlos, Navaratnam, Naveenan, Carroll, Jason S., Zwart, Wilbert, Coombes, R. Charles, Magnani, Luca, Buluwela, Laki, Ali, Simak

“…Estrogen receptor α (ERα) is the key transcriptional driver in a large proportion of breast cancers. We report that APOBEC3B (A3B) is required for regulation…”
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DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation by Faronato, Monica, Nguyen, Van T M, Patten, Darren K, Lombardo, Ylenia, Steel, Jennifer H, Patel, Naina, Woodley, Laura, Shousha, Sami, Pruneri, Giancarlo, Coombes, R Charles, Magnani, Luca

“…The acquisition of endocrine therapy resistance in estrogen receptor α (ERα) breast cancer patients represents a major clinical problem. Notch signalling has…”
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Induction of the TEAD Co-activator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer by Gemma, Carolina, Lai, Chun-Fui, Singh, Anup K, Belfiore, Antonino, Portman, Neil, Milioli, Heloisa Z, Periyasamy, Manikandan, Raafat, Sara, Nicholls, Alyssa J, Davies, Claire M, Patel, Naina R, Simmons, Georgia M, Fan, Hailing, Nguyen, Van T M, Magnani, Luca, Rakha, Emad, Martin, Lesley-Ann, Lim, Elgene, Coombes, R Charles, Pruneri, Giancarlo, Buluwela, Laki, Ali, Simak

“…Resistance to endocrine therapies (ET) is common in estrogen receptor (ER) positive breast cancer, and most relapsed patients die with ET-resistant disease…”
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The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer by Magnani, Luca, Patten, Darren K, Nguyen, Van T M, Hong, Sung-Pil, Steel, Jennifer H, Patel, Naina, Lombardo, Ylenia, Faronato, Monica, Gomes, Ana R, Woodley, Laura, Page, Karen, Guttery, David, Primrose, Lindsay, Fernandez Garcia, Daniel, Shaw, Jacqui, Viola, Patrizia, Green, Andrew, Nolan, Christopher, Ellis, Ian O, Rakha, Emad A, Shousha, Sami, Lam, Eric W-F, Győrffy, Balázs, Lupien, Mathieu, Coombes, R Charles

“…Over 30% of ERα breast cancer patients develop relapses and progress to metastatic disease despite treatment with endocrine therapies. The pioneer factor PBX1…”
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Five-year follow-up of the iBerry Study: screening in early adolescence to identify those at risk of psychopathology in emerging adulthood by Bouter, D C, Ravensbergen, S J, de Neve-Enthoven, N G M, Zarchev, M, Mulder, C L, Hoogendijk, W J G, Roza, S J, Grootendorst-van Mil, N H

“…The iBerry Study, a Dutch population-based high-risk cohort (n = 1022) examines the transition from subclinical symptoms to psychiatric disorders in…”
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