Search Results - "Nguyen, Thuy Tien"

Fluorescent Sensing of a Nerve Agent Simulant with Dual Emission over Wide pH Range in Aqueous Solution by Kim, Youngsam, Jang, Yoon Jeong, Mulay, Sandip V., Nguyen, Thuy‐Tien T., Churchill, David G.

“…A new 1,8‐naphthalimide‐based fluorescent probe for the detection of diethyl cyanophosphonate, a very common nerve agent simulant, is designed, synthesized,…”
Get full text

High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding by Nguyen, Thuy-Tien T., Ramachandran, Sekar, Hill, Matthew J., Cerione, Richard A.

“…The mitochondrial enzyme glutaminase C (GAC) is upregulated in many cancer cells to catalyze the first step in glutamine metabolism, the hydrolysis of…”
Get full text

Penetration of Energized Metal Fragments to Porcine Thoracic Tissues by Nguyen, Thuy-Tien N, Breeze, John, Masouros, Spyros D

“…Energized fragments from explosive devices have been the most common mechanism of injury to both military personnel and civilians in recent conflicts and…”
Get more information

Filament formation drives catalysis by glutaminase enzymes important in cancer progression by Feng, Shi, Aplin, Cody, Nguyen, Thuy-Tien T., Milano, Shawn K., Cerione, Richard A.

“…The glutaminase enzymes GAC and GLS2 catalyze the hydrolysis of glutamine to glutamate, satisfying the ‘glutamine addiction’ of cancer cells. They are the…”
Get full text

KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin by Chang, Wen-Hsuan, Nguyen, Thuy-Tien Thi, Hsu, Chia-Hsin, Bryant, Kirsten L., Kim, Hong Jin, Ying, Haoqiang, Erickson, Jon W., Der, Channing J., Cerione, Richard A., Antonyak, Marc A.

“…Mutations in KRAS frequently occur in human cancer and are especially prevalent in pancreatic ductal adenocarcinoma (PDAC), where they have been shown to…”
Get full text

New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography by Milano, Shawn K., Huang, Qingqiu, Nguyen, Thuy-Tien T., Ramachandran, Sekar, Finke, Aaron, Kriksunov, Irina, Schuller, David J., Szebenyi, D. Marian, Arenholz, Elke, McDermott, Lee A., Sukumar, N., Cerione, Richard A., Katt, William P.

“…Cancer cells frequently exhibit uncoupling of the glycolytic pathway from the TCA cycle (i.e., the “Warburg effect”) and as a result, often become dependent on…”
Get full text

The risk of fragment penetrating injury to the heart by Tsukada, Hirotaka, Nguyen, Thuy-Tien N., Breeze, John, Masouros, Spyros D.

“…Injury due to the penetration of fragments into parts of the body has been the major cause of morbidity and mortality after an explosion. Penetrating injuries…”
Get full text

Neuroimaging Findings in US Government Personnel and Their Family Members Involved in Anomalous Health Incidents by Pierpaoli, Carlo, Nayak, Amritha, Hafiz, Rakibul, Irfanoglu, M. Okan, Chen, Gang, Taylor, Paul, Hallett, Mark, Hoa, Michael, Pham, Dzung, Chou, Yi-Yu, Moses, Anita D, van der Merwe, André J, Lippa, Sara M, Brewer, Carmen C, Zalewski, Chris K, Zampieri, Cris, Turtzo, L. Christine, Shahim, Pashtun, Chan, Leighton, Moore, Brian, Stamps, Lauren, Flynn, Spencer, Fontana, Julia, Tata, Swathi, Lo, Jessica, Fernandez, Mirella A, Lori-Joseph, Annie, Matsubara, Jesse, Goldberg, Julie, Nguyen, Thuy-Tien D, Sasson, Noa, Lely, Justine, Smith, Bryan, King, Kelly A, Chisholm, Jennifer, Christensen, Julie, Magone, M. Teresa, Cousineau-Krieger, Chantal, French, Louis M, Yonter, Simge, Attaripour, Sanaz, Lai, Chen

“…IMPORTANCE: US government personnel stationed internationally have reported anomalous health incidents (AHIs), with some individuals experiencing persistent…”
Get full text

Clinical, Biomarker, and Research Tests Among US Government Personnel and Their Family Members Involved in Anomalous Health Incidents by Chan, Leighton, Hallett, Mark, Zalewski, Chris K, Brewer, Carmen C, Zampieri, Cris, Hoa, Michael, Lippa, Sara M, Fitzgibbon, Edmond, French, Louis M, Moses, Anita D, van der Merwe, André J, Pierpaoli, Carlo, Turtzo, L. Christine, Yonter, Simge, Shahim, Pashtun, Moore, Brian, Stamps, Lauren, Flynn, Spencer, Fontana, Julia, Tata, Swathi, Lo, Jessica, Fernandez, Mirella A, Joseph, Annie-Lori, Matsubara, Jesse, Goldberg, Julie, Nguyen, Thuy-Tien D, Sasson, Noa, Lely, Justine, Smith, Bryan, King, Kelly A, Chisholm, Jennifer, Christensen, Julie, Magone, M. Teresa, Cousineau-Krieger, Chantal, Hafiz, Rakibul, Nayak, Amritha, Irfanoglu, Okan, Attaripour, Sanaz, Lai, Chen, Smith, Wendy B

“…IMPORTANCE: Since 2015, US government and related personnel have reported dizziness, pain, visual problems, and cognitive dysfunction after experiencing…”
Get full text

The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled by Li, Yunxing, Ramachandran, Sekar, Nguyen, Thuy-Tien T., Stalnecker, Clint A., Cerione, Richard A., Erickson, Jon W.

“…The glutaminase C (GAC) isoform of mitochondrial glutaminase is overexpressed in many cancer cells and therefore represents a potential therapeutic target…”
Get full text

Characterizing upper limb function in the context of activities of daily living in CLN3 disease by Hildenbrand, Hanna, Wickstrom, Jordan, Parks, Rebecca, Zampieri, Cris, Nguyen, Thuy‐Tien, Thurm, Audrey, Jenkins, Kisha, Alter, Katharine E., Matsubara, Jesse, Hammond, Dylan, Soldatos, Ariane, Porter, Forbes D., Dang Do, An N.

“…In CLN3 disease, impairments in motor function are frequently reported to have later onset compared to visual and cognitive decline, but upper limb motor…”
Get full text

Development of poly (vinyl alcohol)/agar/maltodextrin coating containing silver nanoparticles for banana (Musa acuminate) preservation by Nguyen, Thuong Thi, Huynh Nguyen, Thuy-Tien, Tran Pham, Bao-Tran, Van Tran, Thuan, Bach, Long Giang, Bui Thi, Phuong Quynh, Ha Thuc, C.N.

“…[Display omitted] •Active nanocomposite coating from PVOH/agar/maltodextrin/AgNPs has been developed.•The addition of AgNPs into PAM coating remarkably…”
Get full text

Restricting Lower Limb Flail is Key to Preventing Fatal Pelvic Blast Injury by Rankin, Iain A., Nguyen, Thuy-Tien, Carpanen, Diagarajen, Clasper, Jonathan C., Masouros, Spyros D.

“…Pelvic vascular injury in the casualty of an explosive insult is a principal risk factor for increased mortality. The mechanism of injury has not previously…”
Get full text

Investigating the effect of multi‐coated hydrogel layer on characteristics of electrospun PCL membrane coated with gelatin/silver nanoparticles for wound dressing application by Nguyen, Tien Ngoc‐Thuy, Do, Thien Bui‐Thuan, Ho, Minh Hieu, Tran, Nam Minh‐Phuong, Dang, Nhi Ngoc‐Thao, Do, Thai Minh, Nguyen, Hoai Thi‐Thu, Phan, Thang Bach, Tran, Quyen Ngoc, Van Vo, Toi, Nguyen, Hiep Thi

“…In this study, the effect of coated hydrogel layer on characteristics of the whole gelatin/silver nanoparticles multi‐coated polycaprolactone membrane…”
Get full text

Pelvic Protection Limiting Lower Limb Flail Reduces Mortality by Rankin, Iain A, Nguyen, Thuy-Tien, Carpanen, Diagarajen, Darwood, Alastair, Clasper, Jonathan C, Masouros, Spyros D

“…Pelvic blast injury is one of the most severe patterns of injury to be sustained by casualties of explosions. We have previously identified the mechanism of…”
Get more information

Non-Lethal Blasts can Generate Cavitation in Cerebrospinal Fluid While Severe Helmeted Impacts Cannot: A Novel Mechanism for Blast Brain Injury by Yu, Xiancheng, Nguyen, Thuy-Tien, Wu, Tianchi, Ghajari, Mazdak

“…Cerebrospinal fluid (CSF) cavitation is a likely physical mechanism for producing traumatic brain injury (TBI) under mechanical loading. In this study, we…”
Get full text

Eco-friendly Synthesis of Novel Phosphorus Flame Retardants for Multiple Purposes by Szolnoki, Beáta, Nguyen Thanh, Thuy Tien, Harakály, György

“…The synthesis methods of most parts of phosphorus (P)-based flame retardants apply harmful and toxic reagents, and the formation of byproducts is often…”
Get full text

The risk of fracture to the tibia from a fragment simulating projectile by Nguyen, Thuy-Tien N., Carpanen, Diagarajen, Stinner, Daniel, Rankin, Iain A., Ramasamy, Arul, Breeze, Johno, Proud, William G., Clasper, Jonathan C., Masouros, Spyros D.

“…Penetrating injuries due to fragments energised by an explosive event are life threatening and are associated with poor clinical and functional outcomes. The…”
Get full text

Gelatine Backing Affects the Performance of Single-Layer Ballistic-Resistant Materials Against Blast Fragments by Nguyen, Thuy-Tien N., Meek, George, Breeze, John, Masouros, Spyros D.

“…Penetrating trauma by energized fragments is the most common injury from explosive devices, the main threat in the contemporary battlefield. Such devices…”
Get full text

Bioinorganic Chemistry of the Alkali Metal Ions by Kim, Youngsam, Nguyen, Thuy-Tien T, Churchill, David G

“…The common Group 1 alkali metals are indeed ubiquitous on earth, in the oceans and in biological systems. In this introductory chapter, concepts involving…”
Get more information