Search Results - "Nguyen, Jonathan"

Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial by Kim, Sungjune, Wuthrick, Evan, Blakaj, Dukagjin, Eroglu, Zeynep, Verschraegen, Claire, Thapa, Ram, Mills, Matthew, Dibs, Khaled, Liveringhouse, Casey, Russell, Jeffery, Caudell, Jimmy J, Tarhini, Ahmad, Markowitz, Joseph, Kendra, Kari, Wu, Richard, Chen, Dung-Tsa, Berglund, Anders, Michael, Lauren, Aoki, Mia, Wang, Min-Hsuan, Hamaidi, Imene, Cheng, Pingyan, de la Iglesia, Janis, Slebos, Robbert J, Chung, Christine H, Knepper, Todd C, Moran-Segura, Carlos M, Nguyen, Jonathan V, Perez, Bradford A, Rose, Trevor, Harrison, Louis, Messina, Jane L, Sondak, Vernon K, Tsai, Kenneth Y, Khushalani, Nikhil I, Brohl, Andrew S

“…Merkel cell carcinoma is among the most aggressive and lethal of primary skin cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1…”
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Routes of influenza transmission by Killingley, Ben, Nguyen‐Van‐Tam, Jonathan

“…Remarkably little is known definitively about the modes of influenza transmission. Thus, important health policy and infection control issues remain…”
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Curious case of a leaky mitochondria by Nguyen, Jonathan T, Kit Chan, Chun, Layton, Jacob, Mnatsakanyan, Nelli, Singharoy, Abhishek

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The curious case of the disassembling ATP synthase studied using molecular dynamics simulations by Layton, Jacob, Kit Chan, Chun, Nguyen, Jonathan T., Mnatsakanyan, Nelli, Singharoy, Abhishek

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Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer by Bora-Singhal, Namrata, Perumal, Deepak, Nguyen, Jonathan, Chellappan, Srikumar

“…Abstract Non–small cell lung cancer (NSCLC) patients have very low survival rates because the current therapeutic strategies are not fully effective. Although…”
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The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis by Mair-Jenkins, John, Saavedra-Campos, Maria, Baillie, J. Kenneth, Cleary, Paul, Khaw, Fu-Meng, Lim, Wei Shen, Makki, Sophia, Rooney, Kevin D., Nguyen-Van-Tam, Jonathan S., Beck, Charles R.

“…Background. Administration of convalescent plasma, serum, or hyperimmune immunoglobulin may be of clinical benefit for treatment of severe acute respiratory…”
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YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self‐Renewal and Vascular Mimicry of Stem‐Like Cells by Bora‐Singhal, Namrata, Nguyen, Jonathan, Schaal, Courtney, Perumal, Deepak, Singh, Sandeep, Coppola, Domenico, Chellappan, Srikumar

“…Non‐small cell lung cancer (NSCLC) is highly correlated with smoking and has very low survival rates. Multiple studies have shown that stem‐like cells…”
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Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic by Fuller, Amy, Hancox, Jennie, Vedhara, Kavita, Card, Tim, Mallen, Christian, Van-Tam, Jonathan S. Nguyen, Abhishek, Abhishek

“…Objectives To explore barriers and facilitators to COVID-19, influenza, and pneumococcal vaccine uptake in immunosuppressed adults with immune-mediated…”
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Disordered regions of respiratory supercomplexes offer new pathways for substrate channeling in crowded membranes by Chan, Chun Kit, Nguyen, Jonathan T., Gupta, Chitrak, Perez, Alberto, Mileykovskaya, Eugenia, Tajkhorshid, Emad, Singharoy, Abhishek

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Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis by Pillai, Smitha, Nguyen, Jonathan, Johnson, Joseph, Haura, Eric, Coppola, Domenico, Chellappan, Srikumar

“…TANK Binding Kinase 1 (TBK1) is a non-canonical IκB kinase that contributes to KRAS-driven lung cancer. Here we report that TBK1 plays essential roles in…”
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Influenza in long‐term care facilities by Lansbury, Louise E., Brown, Caroline S., Nguyen‐Van‐Tam, Jonathan S.

“…Long‐term care facility environments and the vulnerability of their residents provide a setting conducive to the rapid spread of influenza virus and other…”
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Investigation into the application of low melting temperature alloys as wet thermal interface materials by Roy, Chandan K., Bhavnani, Sushil, Hamilton, Michael C., Johnson, R. Wayne, Nguyen, Jonathan L., Knight, Roy W., Harris, Daniel K.

“…The application of low melt alloys (LMAs) containing In, Ga, Sn, and Bi as compliant high performance thermal interface material (TIM) is investigated. The…”
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Genomic and Single-Cell Landscape Reveals Novel Drivers and Therapeutic Vulnerabilities of Transformed Cutaneous T-cell Lymphoma by Song, Xiaofei, Chang, Shiun, Seminario-Vidal, Lucia, de Mingo Pulido, Alvaro, Tordesillas, Leticia, Song, Xingzhi, Reed, Rhianna A, Harkins, Andrea, Whiddon, Shannen, Nguyen, Jonathan V, Segura, Carlos Moran, Zhang, Chaomei, Yoder, Sean, Sayegh, Zena, Zhao, Yun, Messina, Jane L, Harro, Carly M, Zhang, Xiaohui, Conejo-Garcia, José R, Berglund, Anders, Sokol, Lubomir, Zhang, Jianhua, Rodriguez, Paulo C, Mulé, James J, Futreal, Andrew P, Tsai, Kenneth Y, Chen, Pei-Ling

“…Cutaneous T-cell lymphoma (CTCL) is a rare cancer of skin-homing T cells. A subgroup of patients develops large cell transformation with rapid progression to…”
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The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment by Tran, Thai Hoa, Nguyen, Jonathan V, Stecula, Adrian, Akutagawa, Jon, Moorman, Anthony V, Braun, Benjamin S, Sali, Andrej, Mullighan, Charles G, Shah, Neil P, Dai, Yunfeng, Devidas, Meenakshi, Roberts, Kathryn G, Smith, Catherine C, Loh, Mignon L

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Five years of monitoring for the emergence of oseltamivir resistance in patients with influenza A infections in the Influenza Resistance Information Study by Lina, Bruno, Boucher, Charles, Osterhaus, Albert, Monto, Arnold S., Schutten, Martin, Whitley, Richard J., Nguyen‐Van‐Tam, Jonathan S.

“…Background and objectives The Influenza Resistance Information Study (IRIS) was initiated in 2008 to study the emergence of neuraminidase inhibitor (NAI)…”
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Learnings from the vaccines taskforce: an apotheosis in mission, purpose and handling risk by Carroll, Stuart Michael, Van Tam, Jonathan Nguyen, Shaw, Ian, Todd, Ruth, Bell, Eleanor

“…The Vaccines Task Force was established by the UK government in March 2020, with the objective of securing early access to effective COVID-19 vaccines for the…”
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Racial Differences in the Tumor Immune Landscape and Survival of Women with High-Grade Serous Ovarian Carcinoma by Peres, Lauren C, Colin-Leitzinger, Christelle, Sinha, Sweta, Marks, Jeffrey R, Conejo-Garcia, Jose R, Alberg, Anthony J, Bandera, Elisa V, Berchuck, Andrew, Bondy, Melissa L, Christensen, Brock C, Cote, Michele L, Doherty, Jennifer Anne, Moorman, Patricia G, Peters, Edward S, Moran Segura, Carlos, Nguyen, Jonathan V, Schwartz, Ann G, Terry, Paul D, Wilson, Christopher M, Fridley, Brooke L, Schildkraut, Joellen M

“…Tumor-infiltrating lymphocytes (TIL) confer a survival benefit among patients with ovarian cancer; however, little work has been conducted in racially diverse…”
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Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta‐analysis by Aoyagi, Yumiko, Beck, Charles R., Dingwall, Robert, Nguyen‐Van‐Tam, Jonathan S.

“…To estimate the proportion of healthcare workers (HCWs) willing to work during an influenza pandemic and identify associated risk factors, we undertook a…”
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Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria by Li, Meng, Calteau, Alexandra, Semchonok, Dmitry A., Witt, Thomas A., Nguyen, Jonathan T., Sassoon, Nathalie, Boekema, Egbert J., Whitelegge, Julian, Gugger, Muriel, Bruce, Barry D.

“…Photosystem I (PSI) is present as trimeric complexes in most characterized cyanobacteria and as monomers in plants and algae. Recent reports of tetrameric PSI…”
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Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD by Card, Timothy R., Nakafero, Georgina, Grainge, Matthew J., Mallen, Christian D., Van-Tam, Jonathan S. Nguyen, Williams, Hywel C., Abhishek, Abhishek

“…To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) flare. Patients with IBD…”
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