Search Results - "Nguyen, Huy Tram N"
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Go, no-go decision making for phase 3 clinical trials: ACT IV revisited
Published in The lancet oncology (01-12-2017)“…Another comparison for gross total resection and MGMT methylation reported survival of around 24 months in patients with MGMT methylated tumours and 18 months…”
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Epidural Fibrin Sealant Injection for the Management of Cerebrospinal Fluid Leak Following Dural Puncture in Children
Published in Curēus (Palo Alto, CA) (10-02-2020)“…Cerebrospinal fluid (CSF) leak, intracranial hypotension, and postdural puncture headaches are common following dural punctures. Management usually consists of…”
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Phase 2 Study of Bortezomib Combined With Temozolomide and Regional Radiation Therapy for Upfront Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Safety and Efficacy Assessment
Published in International journal of radiation oncology, biology, physics (01-04-2018)“…To assess the safety and efficacy of upfront treatment using bortezomib combined with standard radiation therapy (RT) and temozolomide (TMZ), followed by…”
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The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide
Published in Neuro-oncology (Charlottesville, Va.) (01-12-2015)“…Promoter methylation of O(6)-methylguanine-DNA methyltransferase (MGMT) is an important predictive biomarker in glioblastoma. The T variant of the MGMT…”
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Bevacizumab (Bev) to reduce the negative impact of glioblastoma (GBM) tumor size on survival from first recurrence
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 2052 Background: Bev was FDA approved for recurrent GBM in 2009. However, the survival benefit from Bev in GBM remains to be demonstrated…”
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Molecular Evolution of a Glioblastoma Controlled With Tumor Treating Fields and Concomitant Temozolomide
Published in Frontiers in oncology (15-10-2018)“…Tumor Treating Field (TTFields) therapy has demonstrated efficacy in a Phase 3 study of newly diagnosed glioblastoma (GB) following radiation (RT) and…”
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Vision loss in glioblastoma: Disease mimicking presumed therapeutic toxicity
Published in Neuro-oncology practice (02-11-2018)“…Glioblastoma is the most common and lethal form of primary brain cancer. In the recurrent setting, bevacizumab is a common choice for salvage therapy. Loss of…”
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Epidural Fibrin Sealant Injection for the Management of Cerebrospinal Fluid Leak Following Dural Puncture in Children
Published in Cureus (10-02-2020)Get full text
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