Search Results - "Nguyen, Huong (Marie)"
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Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
Published in Blood (25-08-2016)“…We conducted a genome-wide association study (GWAS) to identify novel predisposition alleles associated with Philadelphia chromosome-negative…”
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2
Discordant aPTT and Anti-Xa Values and Outcomes in Hospitalized Patients Treated with Intravenous Unfractionated Heparin
Published in The Annals of pharmacotherapy (01-02-2013)“…BACKGROUND: Both the activated partial thromboplastin time (aPTT) and anti-Xa assay can be used to monitor unfractionated heparin (UFH). Following…”
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3
Is there a role for the use of IFN-α in primary myelofibrosis?
Published in Hematology (01-12-2012)“…A 62-year-old man with a history of diabetes and hypertension is referred to your hematology clinic for an incidental discovery of anemia. He does not have any…”
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4
Is there a role for the use of IFN-α in primary myelofibrosis?
Published in Hematology (2012)“…A 62-year-old man with a history of diabetes and hypertension is referred to your hematology clinic for an incidental discovery of anemia. He does not have any…”
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5
A Pilot Study of Quantitative MRI Parametric Response Mapping of Bone Marrow Fat for Treatment Assessment in Myelofibrosis
Published in Tomography (Ann Arbor) (01-03-2016)“…Myelofibrosis (MF) is a hematologic neoplasm arising as a primary disease or secondary to other myeloproliferative neoplasms (MPNs). Both primary and secondary…”
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First-in-human phase 1 study of CC-94676, a first-in-class androgen receptor (AR) ligand-directed degrader (LDD), in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)
Published in Journal of clinical oncology (01-02-2024)“…134 Background: Androgen receptor (AR) signaling is the principal driver of PC at all stages. CC-94676 (BMS-986365) is a heterobifunctional, first-in-class,…”
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Tislelizumab (BGB-A317) + concurrent chemoradiotherapy (cCRT) followed by tislelizumab monotherapy for newly diagnosed locally advanced, unresectable, stage III non-small cell lung cancer (NSCLC) in a phase III study (RATIONALE 001)
Published in Journal of clinical oncology (20-05-2019)“…Abstract only TPS8574 Background: cCRT improves survival vs RT alone and is a global standard of care in patients (pts) with stage III NSCLC, but survival…”
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A New Prognostic Model for Response in Myelofibrosis Patients Treated with JAK2 Inhibitors: A Study from Three US Academic Centers
Published in Blood (06-12-2014)“…Background: JAK2 inhibitors have been shown to improve symptoms and produce durable reductions in splenomegaly in patients with myelofibrosis (MF), and…”
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9
FDA-Approved Ruxolitinib in Patients with Myelofibrosis: the Stanford Experience
Published in Blood (16-11-2012)“…Abstract 1747 The oral JAK 1/2 inhibitor ruxolitinib (RUX) was approved in November 2011 for patients (pts) with IPSS intermediate (INT) or high-risk…”
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10
Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms
Published in Journal of the National Comprehensive Cancer Network (01-04-2015)“…The classical Philadelphia chromosome-negative myeloproliferative neoplasms (MPN), which include essential thrombocythemia, polycythemia vera, and…”
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11
Update: a Novel Stratification of Myelofibrosis Patients by Likelihood of Response to JAK2 Inhibitors
Published in Clinical lymphoma, myeloma and leukemia (01-09-2016)Get full text
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12
PI3Kδ Inhibitor Idelalisib Inhibits AKT Signaling In Myelofibrosis Patients On Chronic JAK Inhibitor Therapy
Published in Blood (15-11-2013)“…Myelofibrosis (MF) is characterized by activation of the JAK-STAT pathway, with the JAK2 V617F mutation found in 50-60% of patients. Although JAK inhibitors,…”
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13
ABL001, a Potent, Allosteric Inhibitor of BCR-ABL, Exhibits Safety and Promising Single- Agent Activity in a Phase I Study of Patients with CML with Failure of Prior TKI Therapy
Published in Blood (03-12-2015)“…▪ Background: ABL001 is a potent, specific BCR-ABL inhibitor in development for the treatment of patients with chronic myelogenous leukemia (CML) and…”
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Estimation of JAK2 V617F Prevalence by Detection of the Mutation in Saliva Samples From Online MPN and General Population Cohorts
Published in Blood (16-11-2012)“…Abstract 1737 The somatic JAK2 V617F (V617F) mutation is found in approximately 95% of polycythemia vera (PV) and 50–60% of essential thrombocythemia (ET) and…”
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A Germline Variant in the TERT Gene Is a Novel Predisposition Allele Associated with Myeloproliferative Neoplasms
Published in Blood (16-11-2012)“…Abstract 707 Myeloproliferative neoplasms (MPNs) are disorders that result in unregulated overproduction of one or more myeloid blood cell types by the bone…”
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Correlation of Symptom Assessment with Genotyping Analysis of Saliva Samples in a Large Cohort of Myeloproliferative Neoplasm Patients
Published in Blood (16-11-2012)“…Abstract 1732 In addition to chronic myelogenous leukemia (CML), the classic myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential…”
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