Search Results - "Nguyen, Duy Sinh"
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Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells
Published in Cancer science (01-05-2017)“…The epithelial–mesenchymal transition (EMT) is a crucial morphological event that occurs during progression of epithelial tumors. We reported previously that…”
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Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma
Published in Future oncology (London, England) (01-12-2022)“…This study exploited hepatocellular carcinoma (HCC)-specific circulating DNA methylation profiles to improve the accuracy of a current screening assay for HCC…”
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Multimodal analysis of genome-wide methylation, copy number aberrations, and end motif signatures enhances detection of early-stage breast cancer
Published in Frontiers in oncology (08-05-2023)“…Breast cancer causes the most cancer-related death in women and is the costliest cancer in the US regarding medical service and prescription drug expenses…”
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Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer
Published in Molecular oncology (01-04-2023)“…Breast cancer is the leading cause of cancer death in Vietnamese women, but its mutational landscape and actionable alterations for targeted therapies remain…”
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Tumor genomic profiling and personalized tracking of circulating tumor DNA in Vietnamese colorectal cancer patients
Published in Frontiers in oncology (12-12-2022)“…Colorectal cancer (CRC) is the fifth most common cancer with rising prevalence in Vietnam. However, there is no data about the mutational landscape and…”
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Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort
Published in Frontiers in oncology (05-01-2022)“…Hereditary cancer syndromes (HCS) are responsible for 5-10% of cancer cases. Genetic testing to identify pathogenic variants associated with cancer…”
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A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study
Published in Future science OA (31-12-2024)“…The emergence of multicancer early detection (MCED) tests holds promise for improving early cancer detection and public health outcomes. However, positive MCED…”
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Analytical validation and clinical utilization of K-4CARE™: a comprehensive genomic profiling assay with personalized MRD detection
Published in Frontiers in molecular biosciences (2024)“…Biomarker testing has gradually become standard of care in precision oncology to help physicians select optimal treatment for patients. Compared to single-gene…”
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Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants
Published in Journal of clinical oncology (10-08-2024)“…102 Background: Blood-based multi-cancer early detection (MCED) has emerged as a promising method for enhancing early cancer detection efficiency and…”
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Clinical validation of a ctDNA-Based Assay for Multi-Cancer Detection: An Interim Report from a Vietnamese Longitudinal Prospective Cohort Study of 2795 Participants
Published in Cancer investigation (16-03-2023)“…The SPOT-MAS assay "Screening for the Presence Of Tumor by Methylation And Size" detects the five most common cancers in Vietnam by evaluating circulating…”
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Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization
Published in eLife (11-10-2023)“…Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the…”
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BƯỚC ĐẦU KHẢO SÁT ĐỘT BIẾN GEN BRCA1 VÀ BRCA2 T RONG QUẦN THỂ UNG THƯ BIỂU MÔ BUỒNG TRỨNG NGƯỜI VIỆT NAM BẰNG KỸ THUẬT GIẢI TRÌNH TỰ THẾ HỆ MỚI
Published in Tạp chí khoa học. Chuyên san khoa học tự nhiên (20-03-2020)“…BRCA1 và BRCA2 là hai gen ức chế khối u quan trọng. Việc đột biến hai gen này ở bệnh nhân ung thư biểu mô buồng trứng dòng mầm và dòng sinh dưỡng thì đáp ứng…”
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