Search Results - "Nguyen, Christina"
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Taurine deficiency as a driver of aging
Published in Science (American Association for the Advancement of Science) (09-06-2023)“…Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine…”
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2
Stability of end-of-life preferences: a systematic review of the evidence
Published in JAMA internal medicine (01-07-2014)“…Policies and practices that promote advance care planning and advance directive completion implicitly assume that patients' choices for end-of-life (EOL) care…”
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3
Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice
Published in Frontiers in physiology (19-06-2020)“…Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD…”
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4
Next-generation CRISPR gene-drive systems using Cas12a nuclease
Published in Nature communications (12-10-2023)“…One method for reducing the impact of vector-borne diseases is through the use of CRISPR-based gene drives, which manipulate insect populations due to their…”
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5
Organization of Cancer Specialists in US Physician Practices and Health Systems
Published in Journal of clinical oncology (10-09-2023)“…To describe the supply of cancer specialists, the organization of cancer care within versus outside of health systems, and the distance to multispecialty…”
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A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency
Published in Journal of lipid research (01-03-2022)“…Syndromes associated with LCAT deficiency, a rare autosomal recessive condition, include fish-eye disease (FED) and familial LCAT deficiency (FLD). FLD is more…”
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The involvement of rare disease patient organisations in therapeutic innovation across rare paediatric neurological conditions: a narrative review
Published in Orphanet journal of rare diseases (18-04-2022)“…The patient voice is becoming increasingly prominent across all stages of therapeutic innovation. It pervades research domains from funding and recruitment, to…”
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Baseline [ 68 Ga]Ga-PSMA-11 PET/CT before [ 177 Lu]Lu-PSMA-617 Radioligand Therapy: Value of PSMA-Uptake Thresholds in Predicting Targetable Lesions
Published in Cancers (12-01-2023)“…Baseline uptake on prostate-specific membrane antigen (PSMA)-targeted imaging is a prerequisite for radioligand therapy (RLT) with [177Lu]Lu-PSMA-617. This…”
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‘Advocacy groups are the connectors’: Experiences and contributions of rare disease patient organization leaders in advanced neurotherapeutics
Published in Health expectations : an international journal of public participation in health care and health policy (01-12-2022)“…Introduction Biomedical progress has facilitated breakthrough advanced neurotherapeutic interventions, whose potential to improve outcomes in rare neurological…”
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10
Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes
Published in Reproductive toxicology (Elmsford, N.Y.) (01-01-2016)“…•ADBAC+DDAC subfertility is mediated through both female and male reproductive dysfunction.•In females, ADBAC+DDAC exposure resulted in fewer ovulations, fewer…”
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Digital Biomarker Representing Frailty Phenotypes: The Use of Machine Learning and Sensor-Based Sit-to-Stand Test
Published in Sensors (Basel, Switzerland) (08-05-2021)“…Since conventional screening tools for assessing frailty phenotypes are resource intensive and unsuitable for routine application, efforts are underway to…”
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Harnessing Digital Health to Objectively Assess Functional Performance in Veterans with Chronic Obstructive Pulmonary Disease
Published in Gerontology (Basel) (01-07-2022)“…An early detection of impaired functional performance is critical to enhance symptom management for patients with chronic obstructive pulmonary disease (COPD)…”
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13
Digital cultural heritage in the crossfire of conflict: cyber threats and cybersecurity perspectives
Published in Insights the UKSG journal (07-05-2024)“…In the digital age, the preservation of digital cultural heritage faces unforeseen vulnerabilities during conflicts. This article dismantles the illusion of…”
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Hematologic safety of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer
Published in EJNMMI research (03-07-2021)“…Background Myelosuppression is a potential dose-limiting factor in radioligand therapy (RLT). This study aims to investigate occurrence, severity and…”
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Salvage Radioligand Therapy with Repeated Cycles of 177Lu-PSMA-617 in Metastatic Castration-Resistant Prostate Cancer with Diffuse Bone Marrow Involvement
Published in Cancers (10-08-2021)“…Advanced stage metastatic prostate cancer with extensive bone marrow involvement is associated with a high risk of therapy-induced myelotoxicity and…”
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Impact of [ 177 Lu]Lu-PSMA-617 Radioligand Therapy on Reference Organ Uptake Assessed by [ 68 Ga]Ga-PSMA-11-PET/CT
Published in Cancers (30-07-2023)“…This study aims to assess the change in uptake to reference organs, including the liver, parotid and salivary glands after radioligand therapy (RLT) with […”
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High calcium bioglass enhances differentiation and survival of endothelial progenitor cells, inducing early vascularization in critical size bone defects
Published in PloS one (14-11-2013)“…Early vascularization is a prerequisite for successful bone healing and endothelial progenitor cells (EPC), seeded on appropriate biomaterials, can improve…”
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A Handbook for Supporting Today's Graduate Students
Published in Stylus Publishing LLC (01-04-2022)“…Despite continued growth in enrollments, graduate program attrition rates are of great concern to academic program coordinators. It is estimated that only 40…”
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Epidemiology and outcome of chronic high Epstein‐Barr viral load carriage in pediatric kidney transplant recipients
Published in Pediatric transplantation (01-05-2018)“…The development of EBV infection and PTLD is normally associated with a high EBV viral load in peripheral blood. Observations have previously identified…”
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‘High hopes for treatment’: Australian stakeholder perspectives of the clinical translation of advanced neurotherapeutics for rare neurological diseases
Published in Health expectations : an international journal of public participation in health care and health policy (01-06-2024)“…Introduction Advanced therapies offer unprecedented opportunities for treating rare neurological disorders (RNDs) in children. However, health literacy,…”
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