Search Results - "Nguyen, Ann D"
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1
Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
Published in PloS one (20-11-2015)“…Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer…”
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2
Morphological adrenarche in rhesus macaques: development of the zona reticularis is concurrent with fetal zone regression in the early neonatal period
Published in Journal of endocrinology (01-12-2008)“…Human adrenarche is associated with the establishment of a functional zona reticularis (ZR) and increasing secretion of dehydroepiandrosterone (DHEA) in…”
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3
Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis: PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES
Published in The Journal of biological chemistry (27-11-2009)“…Mounting evidence underscores the importance of protein-protein interactions in the functional regulation of drug-metabolizing P450s, but few studies have been…”
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4
The Developmental Increase in Adrenocortical 17,20-Lyase Activity (Biochemical Adrenarche) Is Driven Primarily by Increasing Cytochrome b5 in Neonatal Rhesus Macaques
Published in Endocrinology (Philadelphia) (01-04-2009)“…Adrenarche is thought to be experienced only by humans and some Old World primates despite observed regression of an adrenal fetal zone and establishment of a…”
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5
Adrenal androgens in humans and nonhuman primates: production, zonation and regulation
Published in Endocrine development (2008)“…The synthesis and secretion of large quantities of the adrenal androgens, dehydroepiandrosterone (DHEA) and its sulfoconjugate DHEA sulfate (DS), is a…”
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6
Gender and gonadal status differences in zona reticularis expression in marmoset monkey adrenals: Cytochrome b5 localization with respect to cytochrome P450 17,20-lyase activity
Published in Molecular and cellular endocrinology (01-02-2007)“…Neonatal marmosets express an adrenal fetal zone comparable to humans. While adult males fail to express a functional ZR, with barely detectable blood DHEA…”
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7
Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis
Published in The Journal of biological chemistry (27-11-2009)“…Mounting evidence underscores the importance of protein-protein interactions in the functional regulation of drug-metabolizing P450s, but few studies have been…”
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8
Male Marmoset Monkeys Express an Adrenal Fetal Zone at Birth, But Not a Zona Reticularis in Adulthood
Published in Endocrinology (Philadelphia) (01-01-2005)“…Neonatal human males produce high levels of dehydroepiandrosterone (DHEA) and its sulfo-conjugated form (DS) that decline within a few months of birth, due to…”
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9
Acute Myocarditis Secondary to Reactivated Chromosomally-Integrated HHV6
Published in Journal of cardiac failure (2017)“…Abstract ciHHV-6 (chromosomally-integrated HHV-6) is an uncommon cause of myocarditis but may be underdiagnosed. We describe a case of reactivated ciHHV-6…”
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10
International Travel for Organ Transplantation: Provider and Patient Perspectives
Published in Transplantation direct (01-08-2024)“…Organ allocation in the United States to non-US citizen, non-US residents who travel for transplant (NC/NRTx) is controversial. Current policies may not be…”
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