Search Results - "Nguyen, Alana T"

Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer by Kasi, Pashtoon Murtaza, Hidalgo, Manuel, Jafari, Mehraneh D., Yeo, Heather, Lowenfeld, Lea, Khan, Uqba, Nguyen, Alana T. H., Siolas, Despina, Swed, Brandon, Hyun, Jini, Khan, Sahrish, Wood, Madeleine, Samstein, Benjamin, Rocca, Juan P., Ocean, Allyson J., Popa, Elizabeta C., Hunt, Daniel H., Uppal, Nikhil P., Garrett, Kelly A., Pigazzi, Alessio, Zhou, Xi Kathy, Shah, Manish A., Hissong, Erika

“…In patients with locally advanced cancer without distant metastases, the neoadjuvant setting presents a platform to evaluate new drugs. For mismatch repair…”
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Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but independent of Th1 and Th2 cells by Rixon, Jordan A, Fong, Kevin D, Morris, Claire, Nguyen, Alana T, Depew, Claire E, McSorley, Stephen J

“…Chlamydia vaccine approaches aspire to induce Th1 cells for optimal protection, despite the fact that there is no direct evidence demonstrating Th1-mediated…”
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A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects by Stewart, Katherine, Gaitan, Yaned, Shafer, Maxwell E R, Aoudjit, Lamine, Hu, Di, Sharma, Richa, Tremblay, Mathieu, Ishii, Hidetaka, Marcotte, Michael, Stanga, Daniela, Tang, You Chi, Boualia, Sami Kamel, Nguyen, Alana H T, Takano, Tomoko, Lamarche-Vane, Nathalie, Vidal, Silvia, Bouchard, Maxime

“…Rho family GTPases act as molecular switches regulating actin cytoskeleton dynamics. Attenuation of their signaling capacity is provided by GTPase-activating…”
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Fighting the enemy within: Systemic immune defense against mucosal Salmonella infection by Nguyen, Alana T., McSorley, Stephen J.

“…•New vaccines are urgently needed for systemic Salmonella infections.•Greater understanding of host immune mechanisms is essential.•Systemic, rather than…”
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Cutting Edge: Optimal Formation of Hepatic Tissue-Resident Memory CD4 T Cells Requires T-bet Regulation of CD18 by Depew, Claire E, Nguyen, Alana T, Franke, Marissa C, Calderon, Jesica, Sciammas, Roger, McSorley, Stephen J

“…CD4 tissue-resident memory T cells (TRMs) allow robust protection of barrier surfaces against pathogens. We investigated the role of T-bet in the formation of…”
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Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses by Ang, Lay Teng, Nguyen, Alana T, Liu, Kevin J, Chen, Angela, Xiong, Xiaochen, Curtis, Matthew, Martin, Renata M, Raftry, Brian C, Ng, Chun Yi, Vogel, Uwe, Lander, Angelika, Lesch, Benjamin J, Fowler, Jonas L, Holman, Alyssa R, Chai, Timothy, Vijayakumar, Siva, Suchy, Fabian P, Nishimura, Toshinobu, Bhadury, Joydeep, Porteus, Matthew H, Nakauchi, Hiromitsu, Cheung, Christine, George, Steven C, Red-Horse, Kristy, Prescott, Joseph B, Loh, Kyle M

“…Stem cell research endeavors to generate specific subtypes of classically defined "cell types." Here, we generate >90% pure human artery or vein endothelial…”
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Gata3 antagonizes cancer progression in Pten-deficient prostates by Nguyen, Alana H T, Tremblay, Mathieu, Haigh, Katharina, Koumakpayi, Ismaël Hervé, Paquet, Marilène, Pandolfi, Pier Paolo, Mes-Masson, Anne-Marie, Saad, Fred, Haigh, Jody J, Bouchard, Maxime

“…Loss of the tumor suppressor PTEN is a common occurrence in prostate cancer. This aberration leads to the ectopic activation of the PI3K-Akt pathway, which…”
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Compound to Clinic? A Preclinical High-throughput Screening Pathway To Expedite Drug Discovery in Bladder Cancer by Conroy, Samantha, Nguyen, Alana H.T.

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Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation by Shafer, Maxwell E.R., Nguyen, Alana H.T., Tremblay, Mathieu, Viala, Sophie, Béland, Mélanie, Bertos, Nicholas R., Park, Morag, Bouchard, Maxime

“…During prostate development, basal and luminal cell lineages are generated through symmetric and asymmetric divisions of bipotent basal cells. However, the…”
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Optimal formation of Hepatic Tissue Resident Memory CD4 T cells Requires T-bet Regulation of CD18 by Depew, Claire E., Nguyen, Alana T., Franke, Marissa C., Calderon, Jesica, Sciammas, Roger, McSorley, Stephen J.

“…Tissue resident memory (TRM) CD4 T cells allow robust protection of barrier surfaces against pathogens. We investigated the role of T-bet in the formation of…”
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Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells by Li, Yi, Yang, Xiaojing, Nguyen, Alana H.T., Brockhausen, Inka

“…Apoptosis has been shown to be associated with altered glycosylation patterns and biosynthesis of glycoproteins. A major cell surface receptor involved in the…”
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Calcineurin A–Binding Protein, a Novel Modulator of the Calcineurin-Nuclear Factor of Activated T-Cell Signaling Pathway, Is Overexpressed in Wilms' Tumors and Promotes Cell Migration by Nguyen, Alana H T, Béland, Mélanie, Gaitan, Yaned, Bouchard, Maxime

“…Current therapeutic strategies against Wilms' tumor (WT) reach 80% to 85% success rate. In spite of this, a remaining 15% to 20% of tumors relapse and are…”
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B7-H3 as a Therapeutic Target in Advanced Prostate Cancer by Guo, Christina, Figueiredo, Ines, Gurel, Bora, Neeb, Antje, Seed, George, Crespo, Mateus, Carreira, Suzanne, Rekowski, Jan, Buroni, Lorenzo, Welti, Jon, Bogdan, Denisa, Gallagher, Lewis, Sharp, Adam, Fenor de la Maza, Maria D., Rescigno, Pasquale, Westaby, Daniel, Chandran, Khobe, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Calì, Bianca, Alimonti, Andrea, Bressan, Silvia, Nguyen, Alana H.T., Shen, Michael M., Hawley, Jessica E., Obradovic, Aleksandar, Drake, Charles G., Bertan, Claudia, Baker, Chloe, Tunariu, Nina, Yuan, Wei, de Bono, Johann S.

“…B7-H3 is overexpressed by the majority of advanced prostate cancers, with its expression associating with alterations of DNA damage repair genes, such as BRCA2…”
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Erratum to “B7-H3 as a Therapeutic Target in Advanced Prostate Cancer” [Eur Urol 2023;83(3):224–38] by Guo, Christina, Figueiredo, Ines, Gurel, Bora, Neeb, Antje, Seed, George, Crespo, Mateus, Carreira, Suzanne, Rekowski, Jan, Buroni, Lorenzo, Welti, Jon, Bogdan, Denisa, Gallagher, Lewis, Sharp, Adam, de la Maza, Maria D. Fenor, Rescigno, Pasquale, Westaby, Daniel, Chandran, Khobe, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Calì, Bianca, Alimonti, Andrea, Bressan, Silvia, Nguyen, Alana H.T., Shen, Michael M., Hawley, Jessica E., Obradovic, Aleksandar, Drake, Charles G., Bertan, Claudia, Baker, Chloe, Tunariu, Nina, Yuan, Wei, de Bono, Johann S.

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A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects: e1005785 by Stewart, Katherine, Gaitan, Yaned, Shafer, Maxwell ER, Aoudjit, Lamine, Hu, Di, Sharma, Richa, Tremblay, Mathieu, Ishii, Hidetaka, Marcotte, Michael, Stanga, Daniela, Tang, You Chi, Boualia, Sami Kamel, Nguyen, Alana HT, Takano, Tomoko, Lamarche-Vane, Nathalie, Vidal, Silvia, Bouchard, Maxime

“…Rho family GTPases act as molecular switches regulating actin cytoskeleton dynamics. Attenuation of their signaling capacity is provided by GTPase-activating…”
Get full text